Results 41 to 50 of about 5,896,523 (307)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Security Analysis in the Migration to Cloud Environments

open access: yesFuture Internet, 2012
Cloud computing is a new paradigm that combines several computing concepts and technologies of the Internet creating a platform for more agile and cost-effective business applications and IT infrastructure.
Eduardo Fernández-Medina   +3 more
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

The Legacy of Nat Sternberg: The Genesis of Cre-lox Technology [PDF]

open access: yesAnnual Review of Virology, 2015
Cre-lox of bacteriophage P1 has become one of the most widely used tools for genetic engineering in eukaryotes. The origins of this tool date to more than 30 years ago when Nat L. Sternberg discovered the recombinase, Cre, and its specific locus of crossover, lox, while studying the maintenance of bacteriophage P1 as a stable plasmid.
Yarmolinsky, Michael, Hoess, Ronald
openaire   +3 more sources

Legacy Good Samaritan community health improvement plan

open access: yes, 2021
Title from PDF cover (viewed on March 31, 2022).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

Legacy System Anti-Patterns and a Pattern-Oriented Migration Response [PDF]

open access: yes, 2000
Mature information systems grow old disgracefully as successive waves of hacking result in accidental architectures which resist the reflection of on-going business process change. Such petrified systems are termed legacy systems.
Lauder, Anthony   +3 more
core   +1 more source

Towards Defect Phase Diagrams: From Research Data Management to Automated Workflows

open access: yesAdvanced Engineering Materials, EarlyView.
A research data management infrastructure is presented for the systematic integration of heterogeneous experimental and simulation data required for defect phase diagrams. The approach combines openBIS with a companion application for large‐object storage, automated metadata extraction, provenance tracking and federated data access, thereby supporting ...
Khalil Rejiba   +5 more
wiley   +1 more source

TRANSFORMATION FRAMEWORK FOR LEGACY SOFTWARE MIGRATION

open access: yesJournal of ICT, 2002
A legacy system is a system that is built using old technologies, but it is still beneficial to an organization. However, today it is facing a great challenge to meet the demands of current applications.
N. I. Yusop   +2 more
doaj  

Current Status and Challenges in Data Collection for Aerospace Coatings Deposited by Plasma Spraying

open access: yesAdvanced Engineering Materials, EarlyView.
An innovative approach has been integrated into the GRENAT project to optimize plasma spraying and coating performance. Raw materials are accelerated and melted in the plasma generated by torches, creating coatings. Monitoring sensors collect process data which are combined with ex situ characterization data.
Lila Randriamananjara   +8 more
wiley   +1 more source

Improving crop salt tolerance through soil legacy effects

open access: yesFrontiers in Plant Science
Soil salinization poses a critical problem, adversely affecting plant development and sustainable agriculture. Plants can produce soil legacy effects through interactions with the soil environments.
Yue Ma   +7 more
doaj   +1 more source

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