Results 111 to 120 of about 2,984,612 (283)

Legal Positivism in American Jurisprudence

open access: yes, 1998
This book is both a work of intellectual history and a contribution to legal philosophy. It represents a serious and philosophically sophisticated guide to modern American legal theory, demonstrating that legal positivism has been a misunderstood and ...
Sebok, Anthony J.
core  

Thomas hardy: positivism and his tragic vision [PDF]

open access: yes, 1989
This thesis constitutes an investigation into the presence of the philosophy of August Comte in the writings of Thomas Hardy, and seeks to explore the contrast between Comtean Positivism and Hardy's tragic vision.
Kupp, Ellen Ericson
core  

Tissue‐Agnostic Cellular Morphometric Biomarkers for Risk‐Adapted Management Across Gastrointestinal Precancerous Lesions and Cancers

open access: yesAdvanced Science, EarlyView.
An interpretable, unsupervised artificial intelligence framework identifies a 13‐cellular morphometric biomarker (CMB) signature from routine H&E whole‐slide images. Validated across 2,602 patients, the fixed signature generalizes across colorectal, gastric, and esophageal tissues without retraining, stratifies prognosis and precancerous lesion risk ...
Pin Wang   +14 more
wiley   +1 more source

A Huaxian Formula Nanoformulation Confers Protection Against Acute Radiation‐Induced Lung Injury by Targeting Ferroptosis

open access: yesAdvanced Science, EarlyView.
An inhalable, nanoengineered herbal therapy achieves protection against acute radiation‐induced lung injury via self‐assembled nanomicelle‐mediated pulmonary targeting and a previously unrecognized dual mechanism that attenuates oxidative stress while inhibiting ferroptosis in alveolar epithelial cells.
Li Quan   +11 more
wiley   +1 more source

Theoretical Disagreement, Legal Positivism and Interpretation

open access: yes, 2019
Ronald Dworkin famously argued that legal positivism is a defective account of law because it has no account of Theoretical Disagreement. In this article I argue that legal positivism—as advanced by H.L.A.
Patterson, Dennis
core   +1 more source

Single‐Cell Profiling Reveals Clonally Expanded CX3CR1+ T Cells in Anti‐NMDA Receptor Encephalitis

open access: yesAdvanced Science, EarlyView.
CX3CR1+ T cells are associated with peripheral and central immune alterations in anti‐NMDA receptor encephalitis (NMDAR‐E). They show potential responsiveness to GluN1 (NR1) peptides, potential interactions with peripheral B cells, clonal expansion, increased CD137/CD154 expression, and inflammatory cytokine production. Their preferential cerebrospinal
Lin Yan   +13 more
wiley   +1 more source

The Straw Man of Legal Positivism [PDF]

open access: yes, 1959
The typical view of many lawyers, philosophers, theologians and other thoughtful persons toward a so-called school of jurisprudence generally known as legal positivism is one of condemnation.
Broden, Thomas F.
core  

Macrophage Dab1 Links Early Hypoxia to Adaptive Angiogenesis to Drive Peripheral Nerve Repair

open access: yesAdvanced Science, EarlyView.
Schematic diagram illustrating the Dab1‐linked hypoxia signaling pathway that accelerates angiogenesis and consequent nerve regeneration. Following PNI, a hypoxic microenvironment develops. Hypoxia induces macrophage Dab1 phosphorylation, resulting in NHE‐1 upregulation, HIF‐1α stabilization, and VEGF‐A expression. This cascade promotes angiogenesis in
Xiongyao Zhou   +14 more
wiley   +1 more source

RADBRUCH’S JUS-NATURALISTIC OVERCOMING OF LEGAL POSITIVISM

open access: yesИстраживања, 2012
Germany legal thought gave in the twentieth century several names of world renown: Emil Lask, Hans Kelsen, Max Weber, Karl Schmidt, Niklas Luman, Arthur Kaufman, Ernst Eduard Hirsch and others.
Radivoj Stepanov
doaj  

Reconstructing Fuller\u27s Argument Against Legal Positivism [PDF]

open access: yes, 2013
The purpose of this essay is to offer a reconstruction of Lon Fuller’s critique of Hart’s legal positivism. I show that contrary to the claims of Fuller’s many critics, one can reconstruct from his work a clear and powerful argument against legal ...
Priel, Dan
core  

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