Results 91 to 100 of about 3,055,137 (258)

A LÓGICA DEDUTIVA SOB A ÓTICA DA INTERPRETAÇÃO JURÍDICA E DA TEORIA DA DECISÃO

open access: yesColloquium Humanarum, 2011
This paper discusses the application of deductive logical reasoning in the interpretation and legal decision, focusing on legal positivism and its base of constitution in a democratic state. The study aims to examine the contours of legal positivism from
Ana Augusta Rodrigues Westin Ebaid
doaj   +1 more source

Legal positivism elements in the lithuanian legal thought and court practice. [PDF]

open access: yes, 2009
The thesis of the master degree paper work is ''Legal Positivism Elements in the Lithuanian Legal Thought and Court Practice''. This work analyses the signs of legal positivism in the Lithuanian legal thought and case law.
Gribėnaitė, Liudvika,
core  

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

open access: yesAdvanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang   +12 more
wiley   +1 more source

Conventions, Disagreements, and (Hart’s) Inclusive Legal Positivism [PDF]

open access: yes
In H.L.A. Hart’s legal positivism, the rule of recognition is a rule that serves as an institutional check to identify the various sources of law and to ensure that laws are legally valid and binding.
Zhou, Boyong
core   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

open access: yesAdvanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing   +10 more
wiley   +1 more source

NORMATIVITAS KEILMUAN HUKUM DALAM PERSPEKTIF ALIRAN PEMIKIRAN NEO-KANTIAN

open access: yesMasalah-Masalah Hukum, 2015
Scientific normativity of law conceived as a character inherent in legal science as a sui generis. Jurisprudence basically study the law, something that initially emerged from the dogmatic belief in philosophy.
FX. Adji Samekto
doaj   +1 more source

The Very Idea of Legal Positivism [PDF]

open access: yes, 2012
Much in recent discussions on legal positivism suggests that the controversy surrounding the notion turns on the distinction between inclusive and exclusive legal positivism.
Romanowicz, Marcin, Paulson, Stanley J.
core  

Transcription Factor HOXC11 Drives Colorectal Cancer Progression and Metastasis via CAMK2A‐Dependent CXCL5 Upregulation

open access: yesAdvanced Science, EarlyView.
HOXC11 drives colorectal cancer progression by transcriptionally activating CAMK2A, which triggers NF‐κB–dependent CXCL5 upregulation. CXCL5–CXCR2 signaling further reinforces HOXC11 expression through the ERK1/2–SP1 axis, forming a prometastatic positive feedback loop that is effectively disrupted by combined CAMK2A and CXCR2 inhibition.
Qingyang Sun   +12 more
wiley   +1 more source

Neuromorphic Devices and Computing for Sensing, Memory, and Control

open access: yesAdvanced Science, EarlyView.
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu   +2 more
wiley   +1 more source

Evaluation of The Requirement of Law’s Conformity to Morality From The Perspective of Legal Positivism In Line With The Theory of Normative Hierarchy

open access: yesİstanbul Hukuk Mecmuası
The hierarchy of norms is determined according to the contents of the norms and their potential normative power based on the requirement of conformance between the norms.
Yahya Berkol Gülgeç
doaj   +1 more source

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