Results 31 to 40 of about 50,942 (171)

Author Correction: Genome-based Salmonella serotyping as the new gold standard

open access: yesScientific Reports, 2020
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Sangeeta Banerji   +4 more
doaj   +1 more source

The amoebal MAP kinase response to Legionella pneumophila is regulated by DupA [PDF]

open access: yes, 2009
The amoeba Dictyostelium discoideum can support replication of Legionella pneumophila. Here we identify the dupA gene, encoding a putative tyrosine kinase/dual-specificity phosphatase, in a screen for D.
Li, Zhiru   +8 more
core   +1 more source

Protein Glutamylation: From Cytoskeleton to Signaling

open access: yesMed Research, EarlyView.
Tubulin glutamylation, γ‐glutamylation, and nontubulin glutamylation are distinct yet interconnected post‐translational modifications that regulate diverse physiological and pathological processes, including cytoskeletal organization, cell cycle progression, immunity, metabolism, and disease development.
Jiayuan Chen   +4 more
wiley   +1 more source

Type I-F CRISPR-Cas Distribution and Array Dynamics in Legionella pneumophila

open access: yesG3: Genes, Genomes, Genetics, 2020
In bacteria and archaea, several distinct types of CRISPR-Cas systems provide adaptive immunity through broadly similar mechanisms: short nucleic acid sequences derived from foreign DNA, known as spacers, engage in complementary base pairing with ...
Shayna R. Deecker   +1 more
doaj   +1 more source

Ruta graveolens L. in Evidence‐Based Phytotherapy: Pharmacological Activities, Bioactive Compounds and Safety

open access: yesPhytotherapy Research, EarlyView.
Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko   +3 more
wiley   +1 more source

Comprehensive evaluation of metagenomic next‐generation sequencing for pathogen identification in patients with suspected infection: Establishment of a standardized validation workflow

open access: yesVIEW, EarlyView.
Comprehensive evaluation of metagenomic next‐generation sequencing for pathogen identification in patients with suspected infection: Establishment of a standardized validation workflow. Abstract Metagenomic next‐generation sequencing (mNGS) enables unbiased identification of pathogens directly from clinical specimens. Despite its growing application in
Wen Shu   +11 more
wiley   +1 more source

Uncovering Gaps in Knowledge: A Survey of Belgian General Practitioners’ Awareness of Legionnaires’ Disease Diagnostic Testing

open access: yesInfectious Disease Reports
Background: The incidence of Legionnaires’ disease (LD) is increasing steadily in Europe. Its early diagnosis by general practitioners (GPs) is crucial for better patient outcomes. Study objectives: This study assessed Belgian GPs’ knowledge about LD and
Marco Moretti   +8 more
doaj   +1 more source

Novel type of pilus associated with a Shiga-toxigenic E. coli hybrid pathovar conveys aggregative adherence and bacterial virulence

open access: yesEmerging Microbes and Infections, 2018
A large German outbreak in 2011 was caused by a locus of enterocyte effacement (LEE)-negative enterohemorrhagic E. coli (EHEC) strain of the serotype O104:H4. This strain harbors markers that are characteristic of both EHEC and enteroaggregative E. coli (
Christina Lang   +6 more
doaj   +1 more source

Spatial Patterns and Associated Factors of Intestinal Antibiotic Resistance Genes in Farmed Bullfrogs From Selected Farms Across Major Production Regions in China

open access: yesIntegrative Zoology, EarlyView.
Across selected bullfrog farms in major Chinese production regions, 106 intestinal ARG subtypes were detected, with tetracycline and sulfonamide resistance genes predominating and clear farm‐level variation. High‐risk ARGs, including ermB, floR, and qnrA, were associated with heavy metals, MGEs, and opportunistic pathogens. These findings highlight the
Yang Xu   +7 more
wiley   +1 more source

Toward understanding the catalytic mechanism for two classes of bacterial phospholipid N‐methyltransferases

open access: yesThe FEBS Journal, EarlyView.
Phospholipid N‐methyltransferases (Pmts) synthesize phosphatidylcholine in many bacteria. In this study, we compared the catalytic mechanisms of two bacterial Pmt classes: the Rhodobacter (R‐) and the Sinorhizobium (S‐) type. Representative enzymes for each class were derived from Rubellimicrobium thermophilum and Agrobacterium tumefaciens ...
Irina Shevyreva   +5 more
wiley   +1 more source

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