Results 41 to 50 of about 31,381 (172)
MedComm, Volume 7, Issue 7, July 2026.Under physiological conditions, pathogenic stimuli activate TLR/IL1‐R signaling, triggering TOLLIP dissociation from IRAK1 and subsequent IRAK1 phosphorylation, TRAF6 ubiquitination, and NF‐κB activation. During SARS‐CoV‐2 infection, viral M protein binds TOLLIP and stabilizes the TOLLIP–IRAK1 complex, thereby suppressing NF‐κB signaling, impairing ...
Yabin Zhang +10 more
wiley +1 more source
Frontiers in Chemistry, 2022 Legionella, a waterborne pathogen, is the main cause of Legionnaires’ disease. Therefore, timely and accurate detection and differentiation of Legionella pneumophila and non-Legionella pneumophila species is crucial. In this study, we develop an easy and
Jungang Du +6 more
doaj +1 more source
The FASEB Journal, Volume 40, Issue 11, 15 June 2026.Legionella pneumophila infection leads to the release of pathogen‐associated molecular patterns, which recruits the adaptor protein MYD88, initiating both activating (e.g., NF‐κB) and inhibitory (e.g., PI3K/AKT) signaling pathways that regulate IL‐12 gene expression.
Kara Vasilew +12 more
wiley +1 more source
Legionella colonisation in hot water systems in care homes from two Danish municipalities
Journal of Water and Health, 2022 Legionnaires' disease is a serious health risk among the elderly. Water systems in care homes are therefore of particular interest. We investigated the levels of culturable Legionella in the hot water systems in care homes in two Danish municipalities ...
Niss Skov Nilsen, Søren Anker Uldum
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, Volume 600, Issue 11, Page 1589-1604, June 2026.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Advanced Science, Volume 13, Issue 33, 15 June 2026.A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park +11 more
wiley +1 more source
Journal of Computer Assisted Learning, Volume 42, Issue 3, June 2026.ABSTRACT Background In collaborative problem‐solving (CPS), individual errors such as failing to share relevant information are common. These moments can hinder performance, but if learners engage with them productively, they may offer powerful learning opportunities.
Constanze Richters +4 more
wiley +1 more source
Revista de Salud Ambiental, 2002 Se exponen las medidas de intervención adoptadas para el estudio y control del brote. Se encontraron 126 instalaciones con riesgo (45 de ellas de alto): 70 torres de refrigeración y similares, 35 fuentes ornamentales, 1 obra con movimiento de tierra y 20
F. Sintas Lozano +5 more
doaj
Macromolecular Materials and Engineering, Volume 311, Issue 6, June 2026.Liquidambar orientalis leaf extract (LOLE) and resin extract (LORE) were incorporated into four hydrogel matrices to obtain bioactive wound dressing films. LOLE‐loaded systems mainly contributed to antioxidant activity, whereas LORE‐loaded systems showed stronger antimicrobial performance. The hydrogels exhibited polymer‐ and extract‐dependent swelling,
Meltem Taş Küçükaydın +4 more
wiley +1 more source