Optimizing production efficiencies of hot water units using building energy simulations : trade-off between Legionella pneumophila contamination risk and energy efficiency [PDF]
, 2019 The energy needed for domestic hot water represents an important share in the total energy use of well-insulated and airtight buildings. One of the main reasons for this high energy demand is that hot water is produced at temperatures above 60°C to ...
De Backer, Lien +2 more
core +1 more source
British Journal of Clinical Pharmacology, Volume 92, Issue 5, Page 1487-1492, May 2026.While providing potentially life‐saving cardiorespiratory support for critically ill patients, extracorporeal membrane oxygenation (ECMO) may detrimentally affect pharmacokinetic (PK) performance and concurrent drug efficacy and safety. We describe a patient with Pneumocystis jirovecii pneumonia (PJP) in the context of acquired immunodeficiency ...
Tom C. Zwart +7 more
wiley +1 more source
Legionella colonisation in hot water systems in care homes from two Danish municipalities
Journal of Water and Health, 2022 Legionnaires' disease is a serious health risk among the elderly. Water systems in care homes are therefore of particular interest. We investigated the levels of culturable Legionella in the hot water systems in care homes in two Danish municipalities ...
Niss Skov Nilsen, Søren Anker Uldum
doaj +1 more source
Characterization of avirulent mutant Legionella pneumophila that survive but do not multiply within human monocytes. [PDF]
, 1987 Legionella pneumophila, the causative agent of Legionnaires' disease, is a Gram-negative bacterium and a facultative intracellular parasite that multiplies in human monocytes and alveolar macrophages. In this paper, mutants of L.
Horwitz, MA
core
Flecainide‐Induced Interstitial Lung Disease: A Case Report and Review of the Literature
Clinical Case Reports, Volume 14, Issue 5, May 2026.ABSTRACT This case describes a rare adverse effect in which the subject developed interstitial lung disease after initiating a class IC antiarrhythmic, flecainide. There is no current treatment recommendation for flecainide‐induced interstitial lung disease.
Elizabeth Jenkins +2 more
wiley +1 more source
Frontiers in Medicine, 2022 BackgroundLegionella spp. has been well-recognized as an important cause of community-acquired pneumonia. Current community-acquired pneumonia guidelines recommended covering the treatment of Legionella because of the high mortality associated with ...
Cheng Lei +29 more
doaj +1 more source
Transposon mutagenesis in a hyper-invasive clinical isolate of Campylobacter jejuni reveals a number of genes with potential roles in invasion [PDF]
, 2010 Transposon mutagenesis has been applied to a hyper-invasive clinical isolate of Campylobacter jejuni, 01/51. A random transposon mutant library was screened in an in vitro assay of invasion and 26 mutants with a significant reduction in invasion were ...
Bagnall, MC +5 more
core +1 more source
Advanced Science, Volume 13, Issue 21, 13 April 2026.Metarhizium anisopliae alleviates the phytotoxic effects of polyethylene nanoplastics (NP) and lead (Pb) in rice by decreasing Pb uptake, restoring antioxidant and hormonal equilibrium, and promoting growth. Additionally, the fungus modifies the rhizosphere microbiota, enhancing both contaminant tolerance and plant growth, thereby effectively ...
Jing Peng +7 more
wiley +1 more source
Guinea pigs sublethally infected with aerosolized Legionella pneumophila develop humoral and cell-mediated immune responses and are protected against lethal aerosol challenge. A model for studying host defense against lung infections caused by intracellular pathogens. [PDF]
, 1987 We have employed the guinea pig model of L. pneumophila infection, which mimics Legionnaires' disease in humans both clinically and pathologically, to study humoral and cell-mediated immune responses to L.
Breiman, RF, Horwitz, MA
core