Results 51 to 60 of about 31,494 (173)

PHLPP is neither a Phosphatase nor a Tumor Suppressor

open access: yesBioEssays, Volume 48, Issue 7, July 2026.
PH domain leucine‐rich repeat protein phosphatases (PHLPP) have been described as Akt phosphatases and tumor suppressors for more than 20 years. Recent evidence, however, indicates that they are pseudophosphatases that lost catalytic activity more than 450 Mya. This article argues that new hypotheses are urgently needed to reorient the field.
Thomas A. Leonard
wiley   +1 more source

Modelo de control y vigilancia en sanidad ambiental basados en sistemas de autocontrol

open access: yesRevista de Salud Ambiental, 2006
En el ámbito ambiental el control de los riesgos para la salud está experimentando cambios importantes en lo referente a su concepción y a la forma de gestión de los mismos desde lo servicios de salud pública. Tradicionalmente la Administración Sanitaria
Loreto Santa Marina Rodríguez   +1 more
doaj   +2 more sources

Validation of a Loop-Mediated Isothermal Amplification-Based Kit for the Detection of Legionella pneumophila in Environmental Samples According to ISO/TS 12869:2012

open access: yesMicroorganisms
Legionella pneumophila is a freshwater opportunistic pathogen and the leading cause of severe pneumonia known as Legionnaires’ disease. It can be found in all water systems and survives in biofilms, free-living amoebae, and a wide variety of facilities ...
Giorgia Caruso   +8 more
doaj   +1 more source

Use of PCR for Diagnosis of Legionella Infection in Hematological Patients [PDF]

open access: yesКлиническая микробиология и антимикробная химиотерапия, 2015
Objective. To assess efficacy of PCR for detection of Legionella in bronchoalveolar lavage (BAL) fluid obtained from hematological patients with pneumonia and acute respiratory failure. Materials and Methods.
Yatsyshina S.B.   +5 more
doaj  

Coronavirus M Protein Hijacks Toll‐Interacting Protein (TOLLIP) to Suppress NF‐κB Signaling and Promote Immune Evasion

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Under physiological conditions, pathogenic stimuli activate TLR/IL1‐R signaling, triggering TOLLIP dissociation from IRAK1 and subsequent IRAK1 phosphorylation, TRAF6 ubiquitination, and NF‐κB activation. During SARS‐CoV‐2 infection, viral M protein binds TOLLIP and stabilizes the TOLLIP–IRAK1 complex, thereby suppressing NF‐κB signaling, impairing ...
Yabin Zhang   +10 more
wiley   +1 more source

On the role of cell chaining in the attenuation of a Listeria monocytogenes divIVA mutant

open access: yesVirulence
Listeria monocytogenes is a human pathogen invading nonphagocytic host cells, replicating within their cytosol, and spreading directly from cell to cell. These processes are mediated by specialized virulence factors but also depend on the DivIVA protein.
Sabrina Wamp   +3 more
doaj   +1 more source

The Establishment of an Indigenous‐Led Drinking Water Monitoring Program Leveraging qPCR and Metagenomics Testing in New Zealand

open access: yesWater Environment Research, Volume 98, Issue 7, July 2026.
An Indigenous‐led monitoring program was established in the South Island of New Zealand to improve local drinking water safety. Advanced sampling techniques were used to identify public health risks and provide assurance that remedial interventions were effective.
Connor Redmile   +7 more
wiley   +1 more source

Novel type of pilus associated with a Shiga-toxigenic E. coli hybrid pathovar conveys aggregative adherence and bacterial virulence

open access: yesEmerging Microbes and Infections, 2018
A large German outbreak in 2011 was caused by a locus of enterocyte effacement (LEE)-negative enterohemorrhagic E. coli (EHEC) strain of the serotype O104:H4. This strain harbors markers that are characteristic of both EHEC and enteroaggregative E. coli (
Christina Lang   +6 more
doaj   +1 more source

The Microbiota of Evaporative Cooling Systems and the Impact of Rainwater as an Alternative Water Source

open access: yesWater Environment Research, Volume 98, Issue 7, July 2026.
The substitution of tap water with rainwater for evaporate cooling systems creates no disadvantage with regard to the microbial safety and might allow a reduction of financial and resource investments. ABSTRACT Climate change and an increasing global population are supposed to cause progressive water shortages in the future.
Nicole van Leuven   +6 more
wiley   +1 more source

How often is a work-up for Legionella pursued in patients with pneumonia? A retrospective study

open access: yesBMC Infectious Diseases, 2011
Background It is unclear how often patients with pneumonia are assessed for Legionella in endemic areas. Additionally, the sensitivity of the IDSA/ATS criteria for recommended Legionella testing is undefined.
Mermel Leonard A   +2 more
doaj   +1 more source

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