Results 51 to 60 of about 76,005 (215)
Type I-F CRISPR-Cas Distribution and Array Dynamics in Legionella pneumophila
G3: Genes, Genomes, Genetics, 2020 In bacteria and archaea, several distinct types of CRISPR-Cas systems provide adaptive immunity through broadly similar mechanisms: short nucleic acid sequences derived from foreign DNA, known as spacers, engage in complementary base pairing with ...
Shayna R. Deecker +1 more
doaj +1 more source
Advanced Science, EarlyView.A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park +11 more
wiley +1 more source
iMeta, EarlyView.The study presents a large‐scale single‐cell transcriptomic atlas profiling over 612,010 peripheral immune cells from 97 individuals to decode the heterogeneity of influenza infection. These findings indicate a fundamental immune dichotomy determining clinical trajectories: a protective, monocyte‐centric antiviral state in mild disease versus a ...
Yi Wang +13 more
wiley +1 more source
Streamlining antibiotic use in community acquired pneumonia: A quality improvement initiative
Journal of Hospital Medicine, EarlyView.Abstract Background Evidence suggests a 3‐day total duration and early transition to oral therapy is safe in hospitalized patients with community acquired pneumonia (CAP)—though such care is not standard in the United States. To implement these evidence‐based practices, a multidisciplinary group led by a hospitalist and antimicrobial stewardship ...
Claire E. Ciarkowski +6 more
wiley +1 more source
The FEBS Journal, EarlyView.Phospholipid N‐methyltransferases (Pmts) synthesize phosphatidylcholine in many bacteria. In this study, we compared the catalytic mechanisms of two bacterial Pmt classes: the Rhodobacter (R‐) and the Sinorhizobium (S‐) type. Representative enzymes for each class were derived from Rubellimicrobium thermophilum and Agrobacterium tumefaciens ...
Irina Shevyreva +5 more
wiley +1 more source
Parenteral iron—Does it increase infection risk?
Vox Sanguinis, EarlyView.Abstract Background and Objectives Iron deficiency (ID) and iron deficiency anaemia (IDA) are prevalent conditions impacting various patient populations, both surgical and non‐surgical conditions. The advent of patient blood management (PBM) has promoted intravenous (IV) iron therapy as an alternative to oral iron and blood transfusions.
Joyisa Deb +7 more
wiley +1 more source
MicroorganismsLegionella pneumophila is a freshwater opportunistic pathogen and the leading cause of severe pneumonia known as Legionnaires’ disease. It can be found in all water systems and survives in biofilms, free-living amoebae, and a wide variety of facilities ...
Giorgia Caruso +8 more
doaj +1 more source
Microbiome, 2023 Background Legionella are parasites of freshwater protozoa, responsible for Legionellosis. Legionella can be found in a variety of aquatic environments, including rivers, lakes, and springs, as well as in engineered water systems where they can ...
Oded Bergman +2 more
doaj +1 more source
Journal of Computer Assisted Learning, Volume 42, Issue 3, June 2026.ABSTRACT Background In collaborative problem‐solving (CPS), individual errors such as failing to share relevant information are common. These moments can hinder performance, but if learners engage with them productively, they may offer powerful learning opportunities.
Constanze Richters +4 more
wiley +1 more source
Frontiers in Chemistry, 2022 Legionella, a waterborne pathogen, is the main cause of Legionnaires’ disease. Therefore, timely and accurate detection and differentiation of Legionella pneumophila and non-Legionella pneumophila species is crucial. In this study, we develop an easy and
Jungang Du +6 more
doaj +1 more source