Legionella pneumophila strain 130b evades macrophage cell death independent of the effector SidF in the absence of flagellin [PDF]
International audienceThe human pathogen Legionella pneumophila must evade host cell death signaling to enable replication in lung macrophages and to cause disease. After bacterial growth, however, L.
Abraham, Gilu+10 more
core +3 more sources
Covalent Coercion by Legionella pneumophila [PDF]
Adenylylation of Rab proteins appears to be an intriguing mechanism that Legionella pneumophila uses to modulate their activity during infection. Now the reverse reaction (deadenylylation) (Neunuebel et al., 2011; Tan and Luo, 2011) and a new posttranslational modification (phosphocholination) of Rab1 (Mukherjee et al., 2011) have been reported.
Aymelt Itzen, Roger S. Goody
openaire +3 more sources
Sessile Legionella pneumophila is able to grow on surfaces and generate structured monospecies biofilms [PDF]
Currently, models for studying Legionella pneumophila biofilm formation rely on multi-species biofilms with low reproducibility or on growth in rich medium, where planktonic growth is unavoidable.
Bergé, Mathieu+3 more
core +1 more source
Biofilms: The Stronghold of Legionella pneumophila [PDF]
Legionellosis is mostly caused by Legionella pneumophila and is defined as a severe respiratory illness with a case fatality rate ranging from 5% to 80%. L. pneumophila is ubiquitous in natural and anthropogenic water systems. L. pneumophila is transmitted by inhalation of contaminated aerosols produced by a variety of devices. While L.
Mena Abdel-Nour+3 more
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Optimizing production efficiencies of hot water units using building energy simulations : trade-off between Legionella pneumophila contamination risk and energy efficiency [PDF]
The energy needed for domestic hot water represents an important share in the total energy use of well-insulated and airtight buildings. One of the main reasons for this high energy demand is that hot water is produced at temperatures above 60°C to ...
De Backer, Lien+2 more
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Phylogenetic analysis reveals an ancient gene duplication as the origin of the MdtABC efflux pump. [PDF]
The efflux pumps from the Resistance-Nodulation-Division family, RND, are main contributors to intrinsic antibiotic resistance in Gram-negative bacteria. Among this family, the MdtABC pump is unusual by having two inner membrane components.
Górecki, Kamil, McEvoy, Megan M
core +2 more sources
Influence of Metal Concentration and Plumbing Materials on Legionella Contamination
Legionella colonization of water supply pipes is a significant public health problem. The objective of this work was to evaluate Legionella colonization in hotel hot water systems and to investigate the relationship between metal concentrations, piping ...
Anita Rakić+2 more
doaj +1 more source
The intracellular pathogen Legionella pneumophila, as well as other Legionella species, utilize the Icm/Dot type-IV secretion system to translocate an exceptionally large and diverse repertoire of effectors into their host cells.
Michael Wexler+4 more
doaj +1 more source
Growth kinetics of environmental Legionella pneumophila isolated from industrial wastewater [PDF]
Wastewater treatment plants are environmental niches for Legionella pneumophila, the most commonly identified causative agent of severe pneumonia known as Legionnaire's disease. In the present study, Legionella pneumophila's concentrations were monitored
Caicedo, C.+3 more
core +1 more source
Ecological distribution of Legionella pneumophila [PDF]
Bacteria were concentrated 500-fold from 20-liter water samples collected from 67 different lakes and rivers in the United States. The data suggest that Legionella pneumophila is part of the natural aquatic environment and that the bacterium is capable of surviving extreme ranges of environmental conditions.
Fliermans, C. B.+5 more
openaire +3 more sources