Results 21 to 30 of about 69,586 (312)

Legionella pneumophila strain 130b evades macrophage cell death independent of the effector SidF in the absence of flagellin [PDF]

open access: yes, 2017
International audienceThe human pathogen Legionella pneumophila must evade host cell death signaling to enable replication in lung macrophages and to cause disease. After bacterial growth, however, L.
Abraham, Gilu   +10 more
core   +3 more sources

Covalent Coercion by Legionella pneumophila [PDF]

open access: yesCell Host & Microbe, 2011
Adenylylation of Rab proteins appears to be an intriguing mechanism that Legionella pneumophila uses to modulate their activity during infection. Now the reverse reaction (deadenylylation) (Neunuebel et al., 2011; Tan and Luo, 2011) and a new posttranslational modification (phosphocholination) of Rab1 (Mukherjee et al., 2011) have been reported.
Aymelt Itzen, Roger S. Goody
openaire   +3 more sources

Sessile Legionella pneumophila is able to grow on surfaces and generate structured monospecies biofilms [PDF]

open access: yes, 2010
Currently, models for studying Legionella pneumophila biofilm formation rely on multi-species biofilms with low reproducibility or on growth in rich medium, where planktonic growth is unavoidable.
Bergé, Mathieu   +3 more
core   +1 more source

Biofilms: The Stronghold of Legionella pneumophila [PDF]

open access: yesInternational Journal of Molecular Sciences, 2013
Legionellosis is mostly caused by Legionella pneumophila and is defined as a severe respiratory illness with a case fatality rate ranging from 5% to 80%. L. pneumophila is ubiquitous in natural and anthropogenic water systems. L. pneumophila is transmitted by inhalation of contaminated aerosols produced by a variety of devices. While L.
Mena Abdel-Nour   +3 more
openaire   +3 more sources

Optimizing production efficiencies of hot water units using building energy simulations : trade-off between Legionella pneumophila contamination risk and energy efficiency [PDF]

open access: yes, 2019
The energy needed for domestic hot water represents an important share in the total energy use of well-insulated and airtight buildings. One of the main reasons for this high energy demand is that hot water is produced at temperatures above 60°C to ...
De Backer, Lien   +2 more
core   +1 more source

Phylogenetic analysis reveals an ancient gene duplication as the origin of the MdtABC efflux pump. [PDF]

open access: yes, 2020
The efflux pumps from the Resistance-Nodulation-Division family, RND, are main contributors to intrinsic antibiotic resistance in Gram-negative bacteria. Among this family, the MdtABC pump is unusual by having two inner membrane components.
Górecki, Kamil, McEvoy, Megan M
core   +2 more sources

Influence of Metal Concentration and Plumbing Materials on Legionella Contamination

open access: yesMicroorganisms, 2022
Legionella colonization of water supply pipes is a significant public health problem. The objective of this work was to evaluate Legionella colonization in hotel hot water systems and to investigate the relationship between metal concentrations, piping ...
Anita Rakić   +2 more
doaj   +1 more source

The Legionella genus core effectors display functional conservation among orthologs by themselves or combined with an accessory protein

open access: yesCurrent Research in Microbial Sciences, 2022
The intracellular pathogen Legionella pneumophila, as well as other Legionella species, utilize the Icm/Dot type-IV secretion system to translocate an exceptionally large and diverse repertoire of effectors into their host cells.
Michael Wexler   +4 more
doaj   +1 more source

Growth kinetics of environmental Legionella pneumophila isolated from industrial wastewater [PDF]

open access: yes, 2020
Wastewater treatment plants are environmental niches for Legionella pneumophila, the most commonly identified causative agent of severe pneumonia known as Legionnaire's disease. In the present study, Legionella pneumophila's concentrations were monitored
Caicedo, C.   +3 more
core   +1 more source

Ecological distribution of Legionella pneumophila [PDF]

open access: yesApplied and Environmental Microbiology, 1981
Bacteria were concentrated 500-fold from 20-liter water samples collected from 67 different lakes and rivers in the United States. The data suggest that Legionella pneumophila is part of the natural aquatic environment and that the bacterium is capable of surviving extreme ranges of environmental conditions.
Fliermans, C. B.   +5 more
openaire   +3 more sources

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