Results 51 to 60 of about 45,537 (226)

Metagenomic next-generation sequencing clinches the diagnosis of Legionella pneumonia in a patient with acute myeloid leukemia: A case report and literature review

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Legionella pneumonia caused by Legionella pneumophila is a multi-system disease that is a life-threatening, acute, and severe form of pneumonia. L. pneumophila is widespread and the clinical manifestations of Legionella pneumonia are similar to those of ...
Siqiang Niu   +5 more
doaj   +1 more source

A large‐scale single‐cell transcriptomic atlas indicates the immune panorama of influenza A infection

open access: yesiMeta, EarlyView.
The study presents a large‐scale single‐cell transcriptomic atlas profiling over 612,010 peripheral immune cells from 97 individuals to decode the heterogeneity of influenza infection. These findings indicate a fundamental immune dichotomy determining clinical trajectories: a protective, monocyte‐centric antiviral state in mild disease versus a ...
Yi Wang   +13 more
wiley   +1 more source

Molecular detection of Legionella: moving on from mip

open access: yesFrontiers in Cellular and Infection Microbiology, 2010
The detection of Legionella pneumophila in environmental and clinical samples is frequently performed by PCR amplification of the mip and/or 16S rRNA genes. Combined with DNA sequencing, these two genetic loci can be used to distinguish different species
Stacey FY Yong   +7 more
doaj   +1 more source

GVPC Medium Manufactured without Oxygen Improves the Growth of Legionella spp. and Exhibits Enhanced Selectivity Properties

open access: yesMicrobiology Spectrum, 2022
Glycine-vancomycin-polymyxin-cycloheximide agar (GVPC) is a recommended medium for the detection of Legionella spp. in water samples. However, its quality could be improved in terms of recovery of Legionella spp. and selectivity properties. Modifications
Pablo Casino   +9 more
doaj   +1 more source

Characterization of avirulent mutant Legionella pneumophila that survive but do not multiply within human monocytes. [PDF]

open access: yes, 1987
Legionella pneumophila, the causative agent of Legionnaires' disease, is a Gram-negative bacterium and a facultative intracellular parasite that multiplies in human monocytes and alveolar macrophages. In this paper, mutants of L.
Horwitz, MA
core  

Toward understanding the catalytic mechanism for two classes of bacterial phospholipid N‐methyltransferases

open access: yesThe FEBS Journal, EarlyView.
Phospholipid N‐methyltransferases (Pmts) synthesize phosphatidylcholine in many bacteria. In this study, we compared the catalytic mechanisms of two bacterial Pmt classes: the Rhodobacter (R‐) and the Sinorhizobium (S‐) type. Representative enzymes for each class were derived from Rubellimicrobium thermophilum and Agrobacterium tumefaciens ...
Irina Shevyreva   +5 more
wiley   +1 more source

Miocardite fulminante a Legionella pneumophila – a propósito dum caso clínico

open access: yesRevista Portuguesa de Cardiologia, 2014
Resumo: A miocardite é uma doença inflamatória do miocárdio. Pode‐se apresentar de forma subtil ou fulminante.Apresenta‐se o caso duma mulher de 39 anos com choque cardiogénico no contexto de miocardite fulminante, com necessidade de colocação de ...
Ana Filipa Damásio   +6 more
doaj   +1 more source

Guinea pigs sublethally infected with aerosolized Legionella pneumophila develop humoral and cell-mediated immune responses and are protected against lethal aerosol challenge. A model for studying host defense against lung infections caused by intracellular pathogens. [PDF]

open access: yes, 1987
We have employed the guinea pig model of L. pneumophila infection, which mimics Legionnaires' disease in humans both clinically and pathologically, to study humoral and cell-mediated immune responses to L.
Breiman, RF, Horwitz, MA
core  

Balancing Building Water Conservation and Microbial Water Quality

open access: yesWater Resources Research, Volume 62, Issue 5, May 2026.
Abstract Flow restrictors are widely used to improve water efficiency by limiting flow rates in faucets and showerheads. While these devices contribute to significant reductions in water consumption and associated energy costs, they may also pose unintended risks to microbial water quality. In healthcare and other high‐risk settings, reduced flow rates
Claire Hayward   +4 more
wiley   +1 more source

Legionella hijacks the host Golgi-to-ER retrograde pathway for the association of Legionella-containing vacuole with the ER.

open access: yesPLoS Pathogens, 2021
Legionella pneumophila (L. pneumophila) is a gram-negative bacterium that replicates in a compartment that resembles the host endoplasmic reticulum (ER). To create its replicative niche, L.
Mio Kawabata   +7 more
doaj   +1 more source

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