Results 61 to 70 of about 30,447 (228)

Contamination status and molecular typing of Legionella pneumophila in artificial water environment in Shanghai hospitals from 2019 to 2020

环境与职业医学, 2023
BackgroundThe incidence of Legionnaires' disease is increasing globally and artificial water environment is becoming a common source of outbreaks. Molecular typing techniques can help prevent and control Legionella.
Jiaying GAO, Lingyue YUAN, Yanxin CHEN, Yong CHEN, Jiayuan LUO, Mingliang CHEN, Min CHEN   +6 more
doaj   +1 more source

The Establishment of an Indigenous‐Led Drinking Water Monitoring Program Leveraging qPCR and Metagenomics Testing in New Zealand

Water Environment Research, Volume 98, Issue 7, July 2026.
An Indigenous‐led monitoring program was established in the South Island of New Zealand to improve local drinking water safety. Advanced sampling techniques were used to identify public health risks and provide assurance that remedial interventions were effective.
Connor Redmile, Donna Sutherland, Megan Devane, William Taylor, Isobel Busby, Anne Glackin, Brent Gilpin, Tim Chambers   +7 more
wiley   +1 more source

Legionella hijacks the host Golgi-to-ER retrograde pathway for the association of Legionella-containing vacuole with the ER.

PLoS Pathogens, 2021
Legionella pneumophila (L. pneumophila) is a gram-negative bacterium that replicates in a compartment that resembles the host endoplasmic reticulum (ER). To create its replicative niche, L.
Mio Kawabata, Honoka Matsuo, Takumi Koito, Misaki Murata, Tomoko Kubori, Hiroki Nagai, Mitsuo Tagaya, Kohei Arasaki   +7 more
doaj   +1 more source

Polyphosphates Attenuate Interleukin‐12 Production in Macrophages Infected With Legionella pneumophila

The FASEB Journal, Volume 40, Issue 11, 15 June 2026.
Legionella pneumophila infection leads to the release of pathogen‐associated molecular patterns, which recruits the adaptor protein MYD88, initiating both activating (e.g., NF‐κB) and inhibitory (e.g., PI3K/AKT) signaling pathways that regulate IL‐12 gene expression.
Kara Vasilew, Archana Jayaraman, Johannes Platten, Shuang Xu, Sarah Josinsky, Julian Roewe, Maximilian Mimmler, Jonathan Kilroy, Fedoua Echahidi, Ziya Kaya, Dario S. Zamboni, Christoph Reinhardt, Markus Bosmann   +12 more
wiley   +1 more source

In vivo efficacy of sivelestat in combination with pazufloxacin against Legionella pneumonia. [PDF]

, 2010
It is important to regulate excessive inflammation when patients with severe infectious disease are treated. Sivelestat sodium hydrate (sivelestat), a neutrophil elastase inhibitor, is used in the treatment of lung injury but its effect on bacterial ...
Yamada, Koichi, Kakeya, Hiroshi, Nobuko Araki, Kamihira, Shimeru, Yasuaki Yamada, Koichi Yamada, Koichi Izumikawa, Araki, Nobuko, Yamamoto, Yoshihiro, Yamada, Yasuaki, Yanagihara, Katsunori, Kohno, Shigeru, Shigeru Kohno, Izumikawa, Koichi, Yoshitomo Morinaga, Katsunori Yanagihara, Masafumi Seki, Hiroshi Kakeya, Yoshihiro Yamamoto, Shimeru Kamihira, Seki, Masafumi, Morinaga, Yoshitomo   +21 more
core   +1 more source

GVPC Medium Manufactured without Oxygen Improves the Growth of Legionella spp. and Exhibits Enhanced Selectivity Properties

Microbiology Spectrum, 2022
Glycine-vancomycin-polymyxin-cycloheximide agar (GVPC) is a recommended medium for the detection of Legionella spp. in water samples. However, its quality could be improved in terms of recovery of Legionella spp. and selectivity properties. Modifications
Pablo Casino, Asunción López, Sara Peiró, Martín Ríos, Santiago Ríos, Aldous Porta, Gemma Agustí, Daniel Asensio, Ana María Marqués, Núria Piqué   +9 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, Volume 600, Issue 11, Page 1589-1604, June 2026.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Legionella control in water systems using copper and silver ion generation systems [PDF]

, 2012
Legionella can cause human disease which can be fatal. Routine monitoring for Legionella in water systems is not recommended by UK authorities. Evidence of the efficacy of control modalities against Legionella in these water systems is, therefore, not
Bedford, Birgitta
core  

Evaluation of Bioaerosol Sampling Techniques for Legionella Pneumophila Coupled with Culture Assay and Quantitative Pcr

, 2012
Efficient bioaerosol sampling methods are required for characterization of exposure risk to airborne pathogenic Legionella pneumophila, which may cause severe pneumonia and death in humans.
CHANG, CHING-WEN;CHOU, FANG-CHEN;HUNG, PEI-YU, 張靜文;周芳禛;洪珮瑜   +1 more
core   +1 more source

Mass‐Produced and High‐Performance Nanowell Biosensor Fabricated via Semiconductor Manufacturing for Rapid and Accurate COVID‐19 Diagnosis in the Clinical Field

Advanced Science, Volume 13, Issue 33, 15 June 2026.
A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park, Zahra Rezaei, Nam Ho Bae, Donggee Rho, Da‐Seul Kim, EunYoung Go, YoungTae Seo, Seok Jae Lee, Won Chan Seo, Luke P. Lee, HeaYeon Lee, Su Ryon Shin   +11 more
wiley   +1 more source