Results 41 to 50 of about 3,805 (169)
Addiction Biology, Volume 30, Issue 8, August 2025.Treadmill exercise improved METH‐induced learning and memory impairment in mice.Transcriptome analysis revealed that exercise modulated key pathways including PI3K‐Akt, mTOR, and Wnt signaling. NFKBIA, CXCL12, and Vav3 were identified as potential mediators of the beneficial effects.
Qiuyue Huang +6 more
wiley +1 more source
Emerging Infectious Diseases, 2017 During the summer of 2015, New York, New York, USA, had one of the largest and deadliest outbreaks of Legionnaires’ disease in the history of the United States. A total of 138 cases and 16 deaths were linked to a single cooling tower in the South Bronx.
Pascal Lapierre +18 more
doaj +1 more source
Molecular Informatics, Volume 44, Issue 5-6, June 2025.We proposed a novel computational method that can search for drug candidate compounds and generate new drug‐like structures considering cell‐specific gene expression patterns in diseased cells. The proposed method is expected to be useful for omics‐based drug discovery.
Chikashige Yamanaka +3 more
wiley +1 more source
The Respiratory Tract Microbiome and Human Health
Microbial Biotechnology, Volume 18, Issue 5, May 2025.The respiratory tract microbiome (RTM) trains the immune system and protects against infections. Changes in the RTM are linked to various respiratory diseases. High‐throughput methodologies and computational biology can improve our understanding of the RTM, paving the way for new diagnostic tools, treatments and preventive strategies to improve ...
Patricia Fernández de Córdoba‐Ansón +4 more
wiley +1 more source
DeepQA: A Unified Transcriptome‐Based Aging Clock Using Deep Neural Networks
Aging Cell, Volume 24, Issue 5, May 2025.DeepQA, a unified aging clock based on mixture of experts which is trained on both healthy and unhealthy subjects. ABSTRACT Understanding the complex biological process of aging is of great value, especially as it can help develop therapeutics to prolong healthy life.
Hongqian Qi +6 more
wiley +1 more source
Legionnaires’ Disease Outbreaks and Cooling Towers, New York City, New York, USA
Emerging Infectious Diseases, 2017 The incidence of Legionnaires’ disease in the United States has been increasing since 2000. Outbreaks and clusters are associated with decorative, recreational, domestic, and industrial water systems, with the largest outbreaks being caused by cooling ...
Robert Fitzhenry +15 more
doaj +1 more source
Epidemiology of Legionnaires’ Disease, Hong Kong, China, 2005−2015
Emerging Infectious Diseases, 2020 We reviewed findings of clinical, epidemiologic, and environmental investigations for 288 confirmed case-patients with Legionnaires’ disease reported in Hong Kong, China, during January 2005−December 2015.
Yiu-Hong Leung +4 more
doaj +1 more source
Cancer Medicine, Volume 14, Issue 6, March 2025.ABSTRACT Background Chronic gut inflammation and dysbiosis contribute significantly to colorectal cancer (CRC) development. Shaoyao decoction (SYD) is a well‐established Chinese medicine prescription. Besides ameliorating CRC via anti‐inflammatory effects, SYD modulates gut microbiota (GM) to improve inflammatory responses in ulcerative colitis (UC ...
Yaojun Rong +8 more
wiley +1 more source
FASEB BioAdvances, Volume 7, Issue 3, March 2025.RNA sequencing, KEGG and GO enrichment analysis showed that Cu‐MON improved ASC cell quality by regulating immune response and promoting paracrine secretion through IL‐17 signaling pathway. Cu‐MON also improved stem cell antiviral ability through Type I interferon signaling pathway.
Ruixin Pang +3 more
wiley +1 more source
Emerging Infectious Diseases, 2017 Legionella longbeachae is the primary cause of legionellosis in Australasia and Southeast Asia and an emerging pathogen in Europe and the United States; however, our understanding of the population diversity of L.
Rodrigo Bacigalupe +3 more
doaj +1 more source