A Reflective Verbalization Strategy to Trigger Alternative Diagnostic Hypotheses
ABSTRACT Rationale Physicians sometimes encounter various types of gut feelings (GFs) during clinical diagnosis. The type of GF addressed in this paper refers to the intuitive sense that the generated hypothesis might be incorrect. An appropriate diagnosis cannot be obtained unless these GFs are articulated and inventive solutions are devised.
Sho Isoda +5 more
wiley +1 more source
Clinical and environmental distribution of legionella pneumophila in a university hospital in italy: efficacy of ultraviolet disinfection [PDF]
The molecular epidemiology of Legionella pneumophila in the 'V. Monaldi' University Hospital was studied. Seven cases of nosocomial Legionnaires' disease were diagnosed between 1999 and 2003.
Albanese Z +8 more
core +1 more source
Diagnostic testing for Legionnaires’ disease
Legionnaires’ disease is commonly diagnosed clinically using a urinary antigen test. The urinary antigen test is highly accurate for L. pneumophila serogroup 1, however other diagnostic tests should also be utilized in conjunction with the urinary ...
David M. Pierre +3 more
doaj +1 more source
Seasonal Host Shifts for Legionella Within an Industrial Water‐Cooling System
Taxonomic profiling for Legionella (the causative agent of Legionnaires' disease) and protist hosts within a water cooling tower showed seasonal peaks for Legionella that were associated with taxonomic shifts in the protist community. Legionella frequency was tracked using amplicon sequencing (blue line) and serogroup profiling (red line).
Suzanne Crull +8 more
wiley +1 more source
Syndromic surveillance for local outbreaks of lower-respiratory infections: would it work? [PDF]
BackgroundAlthough syndromic surveillance is increasingly used to detect unusual illness, there is a debate whether it is useful for detecting local outbreaks.
Cees C van den Wijngaard +7 more
doaj +1 more source
Legionella pneumophila modulates the host cytoskeleton by an effector of transglutaminase activity
Abstract The bacterial pathogen Legionella pneumophila delivers more than 330 effector proteins into host cells through its Dot/Icm type IV secretion system (T4SS) to facilitate its intracellular replication. A number of these effectors modulate organelle trafficking pathways to create a membrane‐bound niche called the Legionella‐containing vacuole ...
Yan Liu, Yao Liu, Zhao‐Qing Luo
wiley +1 more source
Legionella pneumophila strain 130b evades macrophage cell death independent of the effector SidF in the absence of flagellin [PDF]
International audienceThe human pathogen Legionella pneumophila must evade host cell death signaling to enable replication in lung macrophages and to cause disease. After bacterial growth, however, L.
Abraham, Gilu +10 more
core +4 more sources
The Molecular Toolbox for Linkage Type‐Specific Analysis of Ubiquitin Signaling
Ubiquitin modifications regulate virtually all aspects of eukaryotic cell biology through an array of polyubiquitin chain signals that adopt distinct structures, enabling the individual polyubiquitin linkages to mediate specific functions in cells.
Julian Koch +3 more
wiley +1 more source
Nosocomial Legionnaires’ Disease: Clinical and Radiographic Patterns
From 1981 to 1991, 55 patients (33 males, 22 females, mean age 58.6 years) with nosocomial Legionnaires’ disease were studied. The mortality rate was 64%. One-half of the patients developed nosocomial Legionnaires’ disease within three weeks of admission.
Thomas J Marrie +2 more
doaj +1 more source
Exploring Ant‐Mollusk Interactions: Insights From Southern Spain
This study reports new data about ant‐mollusk interactions from accidental field observations, a quantitative analysis of the snail shells found in 16 Messor ant nest cleanings, and a qualitative analysis of 51 additional nests of different species. ABSTRACT Ants occupy a great variety of habitats, perform essential ecological roles, and interact with ...
Jairo Robla +3 more
wiley +1 more source

