Results 111 to 120 of about 12,985,405 (284)

GPi‐DBS for SERAC1‐Related Dystonia‐Parkinsonism

Movement Disorders Clinical Practice, EarlyView.
Vidal Yahya, Alessandro Di Maio, Mauro Treddenti, Ludovica Tundo, Giulia Scacciatella, Costanza Masetti, Marta Pengo, Chiara Casellato, Desiree Lattanzi, Marcello Egidi, Sara Marceglia, Tommaso Bocci, Alberto Priori, Gaia Oggioni   +13 more
wiley   +1 more source

Role of mitochondrial complex I genes in host plant expansion of Bactrocera tau (Tephritidae: Diptera) by CRISPR/Cas9 system

Insect Science, EarlyView.
The role of 3 mitochondrial complex I gene in host expansion of Bactrocera tau was verified by CRISPR/Cas9 gene editing system. A stable homogenous strain (Btndufa7‐/‐) of B.tau was established after silencing Ndufa7. The reduced size of larvae and pupae of Ndufa7 knockout strain was first found.Then different levels of fitness and relative expression ...
Wei Shi, Linsheng He, Ruixiang Li, Jun Cao   +3 more
wiley   +1 more source

Anesthetic Management of a Pediatric Patient with Leigh Syndrome

Brazilian Journal of Anesthesiology, 2013
Background and objectives: Leigh syndrome (LS) is a rare disease caused by abnormalities of mitochondrial energy generation. The central nervous system is most frequently affected, with psychomotor underdevelopment, seizures, nystagmus, ophthalmoparesis,
Ismail Serhat Kocamanoglu, Esra Sarihasan   +1 more
doaj   +1 more source

Downbeat nystagmus: aetiology and comorbidity in 117 patients [PDF]

, 2008
Objectives: Downbeat nystagmus (DBN) is the most common form of acquired involuntary ocular oscillation overriding fixation. According to previous studies, the cause of DBN is unsolved in up to 44% of cases.
Brandt, Thomas, Glaser, Mirjam, Strupp, Michael, Wagner, Judith N.   +3 more
core   +1 more source

Acarbose suppresses symptoms of mitochondrial disease in a mouse model of Leigh Syndrome [PDF]

, 2022
Alessandro Bitto, Anthony S. Grillo, Ian B. Stanaway, Bao Nguyen, Kejun Ying, Herman Tung, Kaleb Smith, Ngoc Hieu Tran, Gunnar Velikanje, Silvan R. Urfer, Jessica M. Snyder, Ernst‐Bernhard Kayser, Lu Wang, Daniel L. Smith, J. Will Thompson, Laura G. Dubois, R. William DePaolo, Matt Kaeberlein   +17 more
openalex   +1 more source

Reply: “Leigh Syndrome Due to the Variant c.1019T>C in COX15”

Movement Disorders Clinical Practice, EarlyView.
Haya S. AlFaris, Sangeetha Yoganathan, Marcus N. Callister, Liali Aljouda, Vivek Pai, Pradeep Krishnan, Andrea LeBlanc Miller, Christos Ganos, Carolina Gorodetsky   +8 more
wiley   +1 more source

Genetic and phenotypic variation in wood tiger moths from the Caucasus: insights into male warning color variation

Insect Science, EarlyView.
Coloration serves several fitness‐related functions, including thermoregulation, immunity, social signaling, sexual selection, and predator avoidance. Consequently, color polymorphism can have a significant impact on a species’ interactions with its environment, including its relationships with predators, prey, and potential mates. The wood tiger moth (
Juan A. Galarza, Ossi Nokelainen, Melanie N. Brien, Cristina Ottocento, Bibiana Rojas, Janne K. Valkonen, Tamar Chunashvili, Tõnis Tasane, Chris D. Jiggins, Johanna Mappes   +9 more
wiley   +1 more source

Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice [PDF]

, 2016
The FDA approved drug rapamycin increases lifespan in rodents and delays age-related dysfunction in rodents and humans. Nevertheless, important questions remain regarding the optimal dose, duration, and mechanisms of action in the context of healthy ...
Anderson, Anisimov, Atarashi, Augustine, Bates, Blackwell, Chen, Dai, de Oliveira, Ericsson, Ericsson, Flynn, Goldman, Halloran, Hard, Harrison, Hothorn, Johnson, Johnson, Johnson, Kaeberlein, Lamming, Majumder, Mannick, Mathew, Miller, Miller, Paulson, Prakash, Ramos, Treuting, Wilkinson, Xu, Zhang   +33 more
core   +1 more source

A STOP‐Gain RNF213 Variant Causes Chorea, Stroke‐Like Episodes, and Leigh Syndrome‐Like Encephalopathy

Movement Disorders, EarlyView.
Roberta Bovenzi, Mariasavina Severino, Jennifer Nichols, Fred Shen, Ignacio J. Keller Sarmiento, Bernabe I. Bustos, Lisa Kinsley, Dimitri Krainc, Niccolò E. Mencacci   +8 more
wiley   +1 more source

Phylosymbiosis and Parallel Geographical Patterns in the Gut Microbiota of Desert‐Dwelling Amphibians and Reptiles

Integrative Zoology, EarlyView.
Host species emerge as a significant contributor to interspecies variations in the gut microbiota of desert‐dwelling amphibians and reptiles, illustrating phylosymbiosis among the studied species. Geographical factors partially account for interpopulation variations in the gut microbiota of Bufotes pewzowi and Teratoscincus przewalskii, with parallel ...
Wei Zhu, Liming Chang, Chunlin Zhao, Bo Cai, Lulu Sui, Cheng Shen, Hanqi Li, Bin Wang, Jianping Jiang   +8 more
wiley   +1 more source