Results 81 to 90 of about 22,192 (205)

Delayed Diagnosis of Tuberous Sclerosis Complex Presenting as Abnormal Uterine Bleeding: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Tuberous sclerosis complex (TSC) is a rare multisystem genetic disorder characterized by the development of hamartomatous lesions in multiple organs. Although neurologic and dermatologic manifestations commonly lead to diagnosis during childhood, some patients remain undiagnosed until adulthood because of atypical presentations.
Kidus Tesfaye Bezabih, Hana Sisay Belay, Merid Lemma Kebede, Abebe Ketema Aderu, Mathyas Dessalegn Gebreyes, Kelil Hussein Jibicho, Adugna Assefa Talemahu, Elias Fikre Merid, Kedir Negesso Tukeni   +8 more
wiley   +1 more source

Intra‐Abdominal Myxoid Leiomyosarcoma With PLAG1 Gene Rearrangement Following Prior Laparoscopic Myomectomy: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT PLAG1 immunohistochemistry and FISH were essential for diagnosis of extra‐uterine myxoid leiomyosarcoma and should be considered in myxoid intra‐abdominal tumors, especially in patients with previous uterine surgery.
Cheng‐En Hsieh, Po‐Hsuan Wu, Chang‐Wei Su, Yu‐Chun Ma, Hsuan‐Ying Huang   +4 more
wiley   +1 more source

Pathology‐Driven Diagnosis of Hereditary Leiomyomatosis and Renal Cell Carcinoma: A Clinicopathological and Genetic Analysis of Three Cases

IJU Case Reports, Volume 9, Issue 5, September 2026.
ABSTRACT Introduction Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) is an autosomal dominant disorder characterized by three principal clinical features: cutaneous leiomyomas (cLMs), uterine leiomyomas, and fumarate hydratase (FH)‐deficient renal cell carcinoma (RCC).
Tomoko Uchiyama, Shunsuke Okazaki, Sayaka Ando, Maiko Takeda, Makito Miyake, Akihiko Yoshizawa   +5 more
wiley   +1 more source

Application of Serum CA125, HE4, ROMA, and CPH‐I in the Preoperative Differentiation of Ovarian Tumors: A Diagnostic Accuracy Study

Journal of Clinical Laboratory Analysis, Volume 40, Issue 17, September 2026.
This study evaluated the diagnostic performance of CA125, HE4, ROMA, and CPH‐I in 345 patients with histologically confirmed ovarian tumors. CPH‐I showed favorable diagnostic performance overall and was particularly valuable in premenopausal women, whereas ROMA‐based strategies demonstrated optimal performance in postmenopausal women.
Weiming Feng, Chunying Zhang, Lingxin Meng, Yifei Chen, Haiyun Yu, Yanhong Zhai, Zheng Cao   +6 more
wiley   +1 more source

Variants associating with uterine leiomyoma highlight genetic background shared by various cancers and hormone-related traits

Nature Communications, 2018
Uterine leiomyomas are common benign tumors. Here, a meta-analysis of two European leiomyoma GWAS uncovers 21 leiomyoma risk variants at 16 loci, providing evidence of genetic overlap between leiomyoma and various benign and malignant tumors and ...
Thorunn Rafnar, Bjarni Gunnarsson, Olafur A. Stefansson, Patrick Sulem, Andres Ingason, Michael L. Frigge, Lilja Stefansdottir, Jon K. Sigurdsson, Vinicius Tragante, Valgerdur Steinthorsdottir, Unnur Styrkarsdottir, Simon N. Stacey, Julius Gudmundsson, Gudny A. Arnadottir, Asmundur Oddsson, Florian Zink, Gisli Halldorsson, Gardar Sveinbjornsson, Ragnar P. Kristjansson, Olafur B. Davidsson, Anna Salvarsdottir, Asgeir Thoroddsen, Elisabet A. Helgadottir, Katrin Kristjansdottir, Orri Ingthorsson, Valur Gudmundsson, Reynir T. Geirsson, Ragnheidur Arnadottir, Daniel F. Gudbjartsson, Gisli Masson, Folkert W. Asselbergs, Jon G. Jonasson, Karl Olafsson, Unnur Thorsteinsdottir, Bjarni V. Halldorsson, Gudmar Thorleifsson, Kari Stefansson   +36 more
doaj   +1 more source

Risk Factors of Uterine Leiomyoma in Women of Reproductive Ages

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2009
BACKGROUND AND OBJECTIVE: Uterine leiomyoma is the most common benign pelvic tumors with an unknown etiology. There are contradictory results about risk factors of uterine leiomyoma which affiliated to genetic or hormonal theories, in different studies ...
SH Sharami,, Z Zahiri,, M Ghanaie
doaj  

Small Extracellular Vesicle and Total Lipid Profiles Provide a Diagnostic Advantage Over CA‐125 Across Ovarian Cancer Subtypes

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
Small extracellular vesicle (sEV) lipid profiles outperform CA‐125 across ovarian cancer histotypes, achieving accuracy up to 0.73 in differential diagnosis and 0.94 in screening. In patients with normal CA‐125 levels, sEV lipids maintain discriminative performance where CA‐125 alone fails. ABSTRACT Ovarian cancer remains the most lethal gynaecological
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Lewis Perrin, Rohan Lourie, Vaibhavi Joshi, Amy E. McCart Reed, Kaltin Ferguson, Aase Handberg, Andreas Möller, Carlos Salomon   +11 more
wiley   +1 more source

Exploring Neutrophil Extracellular Traps in Canine Soft Tissue Sarcomas: A Preliminary Study With Translational Insights

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Neutrophil Extracellular Traps (NETs) in Canine Soft Tissue Sarcomas This study investigated the presence of neutrophil extracellular traps (NETs) in canine soft tissue sarcomas using dual immunohistochemistry for citrullinated histone‐3 and myeloperoxidase.
Burak Yildirim, Volkan Ipek
wiley   +1 more source

Leiomyoma Cutis [PDF]

Proceedings of the Royal Society of Medicine, 1947
G B, Mitchell-Heggs, M H, Small
openaire   +2 more sources

Leiomyoma cutis

Pan African Medical Journal
A fifty-year-old male presented with complaints of multiple, painful, and localized swellings on the left arm for 5 years. To begin with, the swelling was single in number, elevated, erythematous, and associated with itching. It gradually increased in number and size over time and was associated with intense pain.
Aishwarya Kishor Kedar, Rohini Amar Rathod   +1 more
openaire   +3 more sources