Results 61 to 70 of about 22,192 (205)

Update on Menopause Hormone Therapy; Current Indications and Unanswered Questions

Clinical Endocrinology, EarlyView.
ABSTRACT Objective To provide clinicians involved in managing menopause with a summary of current evidence surrounding menopause hormone therapy (MHT). Design The authors evaluate and synthesize existing pooled evidence relating to MHT's clinical indications, efficacy, and safety and explore the limitations of existing data. Patients The review focuses
Annice Mukherjee, Susan R. Davis
wiley   +1 more source

Isolated Perihepatic Peritoneal Leiomyoma: A Case Report

Journal of the Korean Society of Radiology
Peritoneal leiomyomas are extremely rare. Most reported cases are that of disseminated peritoneal leiomyomatosis, making isolated leiomyoma an uncommon occurrence.
Seul Ki Kim, Tae Young Lee
doaj   +1 more source

Biopsy of Iris and Anterior Chamber Tumours: Fine Needle, Minimally Invasive and Excision Techniques ‐ Review

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Several benign, inflammatory and malignant lesions can present as iris or anterior chamber masses, including iris naevi, cysts, adenomas, leiomyomas, nodules, vascular tumours, melanomas, metastases, as well as iris and pigment epithelium adenocarcinomas. Fortunately, benign iris lesions are much more common than malignant tumours and many can
Charles N. J. McGhee, Joevy Z. Lim, Peter W. Hadden, Jie Zhang   +3 more
wiley   +1 more source

A Multicellular Coordinated Network Driving Lymphovascular Space Invasion in Endometrioid Endometrial Carcinoma

Cell Proliferation, EarlyView.
Single‐cell and spatial profiling reveal that lymphovascular space invasion in endometrioid endometrial carcinoma is driven by coordinated interactions among metastatic epithelium, fibroblasts, immune cells, and endothelium. This multicellular network promotes matrix remodelling, angiogenesis, and immune evasion, forming a pro‐metastatic niche that ...
Wendi Guo, Tianxiang Liu, Runling Ren, Na Li, Wenwen Zhang, Jingwen Si, Yongjun Piao, Yuanjing Hu   +7 more
wiley   +1 more source

Clinical and surgical findings in a mare with unilateral ovarian fibroleiomyoma and adhesions

Equine Veterinary Education, EarlyView.
Summary This case report describes the clinical presentation, ultrasonographic findings, surgical management and outcome of a 7‐year‐old Warmblood mare presented for recurrent colic, weight loss and poor performance. Rectal palpation identified a firm mass in the left caudal abdomen, which appeared on ultrasonography as a large, fluid‐filled, cyst‐like
N. Scilimati, P. Berni, E. Blanc, M. Di Pentima, F. Leonardi, S. Napoli, C. Palmieri, M. Ruggeri, R. Gialletti   +8 more
wiley   +1 more source

A guide to transcriptional cyclin‐dependent kinases in cancer

The FEBS Journal, EarlyView.
Transcriptional cyclin‐dependent‐kinases (tCDKs) facilitate gene expression by promoting RNA polymerase II (RNAPII) progression through discrete phases of the transcription cycle. Aberrant tCDK activity is detectable in different human cancers, thereby contributing to de‐regulated gene expression programs that drive oncogenic phenotypes.
Jennifer R. Devlin, Salla Kyheröinen, Ricky W. Johnstone   +2 more
wiley   +1 more source

A Rare Case of Giant Leiomyoma in the Space of Retzius

Case Reports in Obstetrics and Gynecology
Leiomyoma are benign tumors of smooth muscle origin. Uterine leiomyoma are extremely common; leiomyoma in extraperitoneal spaces, however, are not. There have been several documented cases of leiomyoma in retroperitoneal spaces, though the majority of ...
Emma Barr, Alireza Abidi
doaj   +1 more source

Bladder leiomyoma

Urology Annals, 2017
Leiomyomas of the bladder constitute
Jose Eduardo Mendes, Ana Vaz Ferreira, Sara Alcobia Coelho, Carolina Gil   +3 more
openaire   +3 more sources

Cutaneous Leiomyosarcoma of the Skin: An Updated Review of Epidemiology, Pathogenesis, and Management

International Journal of Dermatology, EarlyView.
This review provides an update on the epidemiology, pathogenesis, and clinical/histologic features of cutaneous leiomyosarcoma. Prognostic factors (e.g., depth of tumor involvement, grade, etc.) that can facilitate risk stratification are also discussed, as are treatment approaches for this rare malignancy.
Tejas P. Joshi, Natalie Garcia, Malak Husseinali, Nabeeha Engineer, Ikue Shimizu   +4 more
wiley   +1 more source

Efficacy of Endoscopic Ultrasound‐guided Fine Needle Biopsy With Simplified Macroscopic On‐site Evaluation (With Video)

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Background and Aims With advances in preoperative chemotherapy and comprehensive genomic profiling, endoscopic ultrasound‐guided fine needle biopsy (EUS‐FNB) has become vital for diagnosing pancreatic and peridigestive tract lesions. However, evidence remains limited regarding the performance of new‐generation puncture needles and simplified ...
Kento Shionoya, Ryosuke Tonozuka, Shuntaro Mukai, Yuki Joyama, Takayoshi Tsuchiya, Reina Tanaka, Kenjiro Yamamoto, Kazumasa Nagai, Yukitoshi Matsunami, Hiroyuki Kojima, Hirohito Minami, Noriyuki Hirakawa, Kyoko Asano, Takao Itoi   +13 more
wiley   +1 more source