Results 31 to 40 of about 40,218 (214)

Anti-proliferative but not anti-angiogenic tyrosine kinase inhibitors enrich for cancer stem cells in soft tissue sarcoma. [PDF]

, 2014
BackgroundIncreasing studies implicate cancer stem cells (CSCs) as the source of resistance and relapse following conventional cytotoxic therapies. Few studies have examined the response of CSCs to targeted therapies, such as tyrosine kinase inhibitors ...
Ames, Erik, Borys, Dariusz, Canter, Robert J, Chen, Mingyi, Grossenbacher, Steven K, Li, Chin-Shang, Mac, Stephanie, Monjazeb, Arta M, Murphy, William J, Sayers, Thomas J, Smith, Rachel C, Tellez, Joe   +11 more
core   +2 more sources

Imaging Findings of Leiomyosarcoma Arising from the Descending Colon Which Presented as a Large Mass in the Retroperitoneum: A Case Report

대한영상의학회지, 2017
Leiomyosarcoma is a malignant tumor of smooth muscle cells and it usually originates from the uterus and the retroperitoneum. Leiomyosarcoma of the gastrointestinal tract is rare and leiomyosarcoma of the colon in even more rare, accounting for less than
Yoogi Cha, Young Hwan Lee, Kwon-Ha Yoon, Ki Jung Yun   +3 more
doaj   +1 more source

The imaging and pathological features of metastatic leiomyosarcoma in the gallbladder

Rare Tumors, 2016
Uterine leiomyosarcoma is a rare and aggressive malignancy with poor overall prognosis. There have been few reports of metastatic leiomyosarcoma in the gallbladder.
Yi Guo, Eleanor Chen, Darin J. Davidson, Venu G. Pillarisetty, Robin L. Jones, Seth M. Pollack   +5 more
doaj   +1 more source

A patient-derived orthotopic xenograft (PDOX) mouse model of a cisplatinum-resistant osteosarcoma lung metastasis that was sensitive to temozolomide and trabectedin: implications for precision oncology. [PDF]

, 2017
In the present study, we evaluated the efficacy of trabectedin (TRAB) and temozolomide (TEM) compared to cisplatinum (CDDP) on a patient-derived orthotopic xenogrraft (PDOX) of a lung-metastasis from an osteosarcoma of a patient who failed CDDP therapy ...
Dry, Sarah M, Eilber, Fritz C, Elliott, Irmina, Hoffman, Robert M, Igarashi, Kentaro, Kawaguchi, Kei, Kiyuna, Tasuku, Li, Yunfeng, Miyake, Kentaro, Murakami, Takashi, Nelson, Scott D, Russell, Tara A, Singh, Arun S, Tsuchiya, Hiroyuki, Yanagawa, Jane, Zhang, Yong   +15 more
core   +1 more source

Primary leiomyosarcoma of kidney: A rare case report

Muller Journal of Medical Sciences and Research, 2015
Primary leiomyosarcoma of kidney is extremely rare tumour accounting for 0.12% of renal tumours. Radiological investigations are not able to differentiate between leiomyosarcoma and sarcomatoid renal cell carcinoma.
Pooja Srivastava, Rajni Prasad, Geetika Khanna   +2 more
doaj   +1 more source

Hypovolemic shock and hemoperitoneum from spontaneous avulsion of a large pedunculated uterine leiomyoma [PDF]

, 2017
Hemoperitoneum with hypovolemic shock from avulsion of a pedunculated leiomyoma is a rare but highly fatal condition that can occur spontaneously or as a result of trauma.
Adamo, Robert, Kaushik, Chhavi, Mizrahi, Daniel J.   +2 more
core   +2 more sources

Metastatic Uterine Leiomyosarcoma in the Upper Buccal Gingiva Misdiagnosed as an Epulis [PDF]

, 2014
Uterine leiomyosarcoma (LMS) is a rare tumor constituting 1% of all uterine malignancies. This sarcoma demonstrates an aggressive growth pattern with an high rate of recurrence with hematologic dissemination; the most common sites are lung, liver, and ...
Alesini F, Bartoli D, Battisti A, Bosco S, Cassoni A, Conte D, Lembo A, Pagnoni M, Terenzi V, Valentini V, Zadeh OR   +10 more
core   +2 more sources

Gastric Metastasis from a Primary Renal Leiomyosarcoma

Case Reports in Gastroenterology, 2012
Primary leiomyosarcoma of the kidney is rare. Here we report a case of metastasis of this tumor to the stomach. A 73-year-old man visited our hospital suffering from general weakness and intermittent tarry stools.
Satoshi Yodonawa, Isao Ogawa, Susumu Yoshida, Hiromichi Ito, Akinori Kato, Ryoko Kubokawa, Emika Tokoshima, Hiroaki Shimoyamada   +7 more
doaj   +1 more source

Temozolomide combined with irinotecan regresses a cisplatinum-resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX) precision-oncology mouse model. [PDF]

, 2017
Relapsed osteosarcoma is a recalcitrant tumor. A patient's cisplatinum (CDDP)-resistant relapsed osteosarcoma lung metastasis was previously established orthotopically in the distal femur of mice to establish a patient-derived orthotopic xenograft (PDOX)
Dry, Sarah M., Eckardt, Mark A., Eilber, Fritz C., Elliott, Irmina A., Hayashi, Katsuhiro, Hoffman, Robert M., Igarashi, Kentaro, Kawaguchi, Kei, Kimura, Hiroaki, Kiyuna, Tasuku, Li, Yunfeng, Miwa, Shinji, Miyake, Kentaro, Miyake, Masuyo, Nelson, Scott D., Russell, Tara A., Singh, Arun S., Tsuchiya, Hiroyuki, Yamamoto, Norio, 三輪, 真嗣, 五十嵐, 健太郎, 土屋, 弘行, 山本, 憲男, 林, 克洋   +23 more
core   +1 more source

Primary Leiomyosarcoma of the Ureter

Asian Journal of Surgery, 2008
Leiomyosarcoma is a rarely seen neoplasm of the ureter, with less than 20 cases being reported in the literature to date. It is important to distinguish leiomyosarcoma from rhabdomyosarcoma, with the aid of immunohistochemical markers.
Chen Lv, Ning Chen, Xuan Zhu, Xuanzhi Zhang, Zhaohui Zhong   +4 more
doaj   +1 more source