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Zoonoses and Public Health, Volume 73, Issue 4, Page 314-325, June 2026.ABSTRACT Introduction Canine Leishmaniasis is a vector‐borne zoonotic disease caused by several species of protozoa of the genus Leishmania. In the state of Rio de Janeiro (RJ), Leishmania braziliensis is the most prevalent species causing tegumentary leishmaniasis (TL) and Leishmania infantum is the main causative agent of visceral leishmaniasis (VL).
Luciana de Freitas Campos Miranda +10 more
wiley +1 more source
An outbreak of human Leishmania (Viannia) braziliensis infection [PDF]
Memórias do Instituto Oswaldo Cruz, 1991 The occurrence of acute cutaneous leishmaniasis among inhabitants of 10 farms within 10 Km of the hamlet of Corte de Pedra, Bahia, Brazil was studied prospectively from 1984-1989. A mean population of 1,056 inhabitants living in 146 houses were visited every 6 months and the number of skin ulcers recorded.
França, F. +12 more
openaire +5 more sources
Memorias do Instituto Oswaldo Cruz, 1986 Lutzomyia (N.) whitmani foi infectada em lesões leishmanióticas de três de nove cães parasitados por Leishmania braziliensis braziliensis . Os índices de infecção desses flebotomíneos foram 8,3% (1/12), 7,1% (1/14) e 1,8% (3,160), respectivamente.
Julio A. Vexenat +2 more
doaj +1 more source
Exploring 6‐Hydroxy‐3‐Aryl/Heteroarylcoumarins as Promising Candidates Against Trypanosoma cruzi
ChemMedChem, Volume 21, Issue 9, 14 May 2026.New therapies are urgently needed for Chagas disease, and screening of 6‐hydroxy‐3‐aryl/heteroarylcoumarin derivatives identified highly selective compounds with potent activity against T. cruzi. In particular, derivative 1f showed submicromolar trypomastigote potency, dual‐stage activity, and inhibition of amastigote‐to‐trypomastigote differentiation,
C. N. Pereira +7 more
wiley +1 more source
Anti-leishmanial Activity of Justicidone and its Synthetic Precursors
Natural Product Communications, 2007 Justicidone, a C-5, C-8 dioxo-lignan of the arylnaphthalene type isolated from Justicia hyssopifolia, and its synthetic precursors were tested for the activity against Leishmania braziliensis and Leishmania amazonensis promastigotes in vitro. Justicidone
Carlos José Boluda +8 more
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Memorias do Instituto Oswaldo Cruz, 2003 Leishmania (V.) braziliensis M2903 presents a small linear and stable 245 kb chromosome originating from a genomic amplification. Similar amplifications present in other species of Leishmania contain a gene coding for a biopterin transporter.
MCR Sampaio, YM Traub-Cseko
doaj +1 more source
Structural basis of secreted acid phosphatase polymerization in the Leishmania parasite
Protein Science, Volume 35, Issue 5, May 2026.Abstract Enzymes that assemble into filaments typically transition between protomeric and polymeric states in response to cellular conditions. In contrast, the secreted acid phosphatase (SAP) of Leishmania, one of the most abundant extracellular glycoproteins produced by the parasite and regarded as a major virulence factor in the neglected tropical ...
Priyanka Bose +4 more
wiley +1 more source
Peptides as a Therapeutic Alternative Against Leishmaniasis: A Scoping Review
Chemical Biology &Drug Design, Volume 107, Issue 5, May 2026.This scoping review of 79 studies identified 231 antimicrobial peptides with anti‐Leishmania activity, including natural‐derived and synthetic peptides (inspired by natural sources or developed through rational design). Most were evaluated in vitro against promastigote and/or amastigote forms, with synthetic peptides showing a more promising effect ...
Maria Eduarda da Veiga Oliveira +3 more
wiley +1 more source
Brazilian Archives of Biology and Technology, 2005 DNA hybridisation, using probes labelled with 32P, was used to type Leishmania samples isolated from patients living in endemic areas of Mato Grosso State (Brazil), and clinically diagnosed as having tegumentary leishmaniasis.
Antero Silva Ribeiro de Andrade +5 more
doaj +1 more source
Tegumentary Leishmaniasis Associated With Immune Reconstitution in an HIV Patient—A Case Report
Parasite Immunology, Volume 48, Issue 5, May 2026.ABSTRACT HIV‐associated Immune Reconstitution Inflammatory Syndrome (IRIS) may significantly alter the immunopathological presentation of American Tegumentary Leishmaniasis (ATL), occasionally causing paradoxical clinical exacerbations. We report the long‐term follow‐up of a 39‐year‐old female coinfected with HIV and disseminated mucocutaneous ...
Marilia Brasil Xavier +9 more
wiley +1 more source