Results 41 to 50 of about 10,019 (223)

Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva, Monique Mantovani, Maria E. S. D. Lino, Aline O. Albuquerque, João H. M. da Silva, Ronaldo A. P. Nagem, Adriana L. Rojas, Geraldo R. Sartori, Eduardo Horjales, David Campbell, Otavio H. Thiemann   +10 more
wiley   +1 more source

Infecção natural por Leishmania sp. em flebotomíneos capturados no foco de transmissão de Leishmaniose Tegumentar Americana no município de Piçarras, litoral norte do Estado de Santa Catarina e identificação específica do parasito em amostras clínicas e em cepas isoladas de pacientes. [PDF]

, 2008
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.As Leishmanioses são doenças infecto-parasitárias causadas por protozoários do gênero Leishmania, que acometem cerca de 12 milhões de indivíduos em 88 países
Bittencourt, Ize de Aguiar
core  

Minor temperature shifts do not affect chromosomal ploidy but cause transcriptomic changes in Leishmania braziliensis promastigotes in vitro [PDF]

Memorias do Instituto Oswaldo Cruz, 2020
BACKGROUND The leishmaniases are complex neglected diseases caused by protozoan parasites of the genus Leishmania. Leishmania braziliensis is the main etiological agent of cutaneous leishmaniasis in the New World. In recent studies, genomic changes such
Nathalia Ballesteros, Nubia M Vásquez, Luz H Patiño, Lissa Cruz-Saavedra, Juan David Ramírez   +4 more
doaj   +1 more source

Thymus and Leishmania at the Crossroads: Autoimmunity and Cancer

Immunology, Volume 178, Issue 3, Page 377-386, July 2026.
Conceptual ‘Crossroads Model’ linking Leishmania, thymic infection and immune dysregulation: an integrative model is proposed in which Leishmania infection disrupts thymic architecture and stromal–thymocyte interactions. These alterations converge to promote defective tolerance, increased autoimmune risk and a microenvironment permissive to malignant ...
Alef Batista Bezerra Barros, Gabriel Augusto Leite, Arthur Gomes de Andrade, Maria Danielma dos Santos Reis, Luiz Henrique Agra Cavalcante‐Silva, Marvin Paulo Lins   +5 more
wiley   +1 more source

Clonagem e expressão da enzina tripanotiona redutase de Leishmania braziliensis e atividade leishmanicida de chalconas [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Programa de Pós-graduação em Biotecnologia, Florianópolis, 2011O presente estudo teve por objetivo avaliar atividade leishmanicida in vitro de chalconas trimetoxiladas contra formas ...
Nunes, Rebeca Körting
core  

Is it time to revise the nomenclature of Leishmania?

, 2010
Leishmania is notable for a large number of described species. Molecular phylogenies of Leishmania have increasingly suggested that the number of species could be too large.
Mauricio, Isabel, Gabriele Schönian, Isabel Mauricio, Cupolillo, Elisa, Elisa Cupolillo, Schönian, Gabriele   +5 more
core   +1 more source

Potential vectors of Leishmaniases in the Environmental Protection Area and Tinguá Federal Biological Reserve, Municipality of Nova Iguaçu, Rio de Janeiro, Brazil

Medical and Veterinary Entomology, Volume 40, Issue 2, Page 246-259, June 2026.
This study was to describe the composition of sand fly fauna, detect potential vectors of Leishmania spp. in the Tinguá district, an ATL endemic, Rio de Janeiro, Brazil. Seven species of vectorial importance in the epidemiological cycle of leishmaniasis was observed: Nyssomyia intermedia, Migonemyia migonei, Pintomyia fischeri, Psychodopygus hirsutus ...
Antônio L. F. Santana, Alfredo C. R. Azevedo, Margarete M. S. Afonso, Bruno M. Carvalho, Vanessa R. Vieira, Simone M. Costa, Júlia S. Silva, Thais A. Pereira, Daniela P. Pereira, Maurício L. Vilela   +9 more
wiley   +1 more source

The role of leishmania proteophosphoglycans in sand fly transmission and infection of the Mammalian host. [PDF]

, 2012
Leishmania are transmitted by the bite of their sand fly vector and this has a significant influence on the virulence of the resulting infection. From our studies into the interaction between parasite, vector, and host we have uncovered an important ...
Rogers, Matthew E, Matthew Edward Rogers, Matthew E. Rogers   +2 more
core   +1 more source

Clonal variation within a mucosal isolate derived from a patient with Leishmania (Viannia) braziliensis infection Variação clonal de um isolado derivado de um paciente com infecção mucosa pela Leishmania (Viannia) braziliensis

Revista do Instituto de Medicina Tropical de São Paulo, 1991
Three isolates over 5 years from a patient with persistent relapsing mucosal leishmaniasis due to Leishmania (Viannia) braziliensis and 7 clones from one of these isolates were studied by zymodemes and scrodemes analysis.
César Augusto Cuba-Cuba, David Evans, Ana de Cassia Rosa, Philip Davis Marsden   +3 more
doaj   +1 more source

The spiny rat Proechimys guyannensis (Rodentia: Echimydae) fails to respond to intradermal inoculation with Leishmania (Viannia) braziliensis [PDF]

Acta Amazonica, 2015
Leishmaniasis a disease of worldwide occurrence is caused by protozoa of the Leishmania genus. In Brazil, Leishmania (Viannia) braziliensis is the main parasite responsible for the American cutaneous leishmaniasis.
Stela Rechinelli PASSOS, Ana Paula MADUREIRA, Sayanne Luns Hatum de ALMEIDA, Marcos Santos ZANINI   +3 more
doaj   +2 more sources