Infecção natural por Leishmania sp. em flebotomíneos capturados no foco de transmissão de Leishmaniose Tegumentar Americana no município de Piçarras, litoral norte do Estado de Santa Catarina e identificação específica do parasito em amostras clínicas e em cepas isoladas de pacientes. [PDF]
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.As Leishmanioses são doenças infecto-parasitárias causadas por protozoários do gênero Leishmania, que acometem cerca de 12 milhões de indivíduos em 88 países
Bittencourt, Ize de Aguiar
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Is it time to revise the nomenclature of Leishmania?
Leishmania is notable for a large number of described species. Molecular phylogenies of Leishmania have increasingly suggested that the number of species could be too large.
Mauricio, Isabel +5 more
core +1 more source
The molecular epidemiology and phylogeography of Trypanosoma cruzi and parallel research on Leishmania: looking back and to the future. [PDF]
Trypanosoma cruzi is the protozoan agent of Chagas disease, and the most important parasitic disease in Latin America. Protozoa of the genus Leishmania are global agents of visceral and cutaneous leishmaniasis, fatal and disfiguring diseases.
Fitpatrick, S. +15 more
core +1 more source
Descreve-se um foco de leishmaniose tegumentar americana abrangendo quatro localidades dos municípios de Viana e Cariacica situados próximo ao litoral do Estado do Espírito Santo, Brasil.
Gelcilio Coutinho Barros +7 more
doaj +1 more source
Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva +10 more
wiley +1 more source
The aim of this study was to synthesize several small molecules of the type 5-nitroimidazole-sulfanyl and evaluate biological properties against the main Leishmania species that cause cutaneous leishmaniasis in Venezuela.
Charris, Jaime E. +7 more
core +1 more source
Minor temperature shifts do not affect chromosomal ploidy but cause transcriptomic changes in Leishmania braziliensis promastigotes in vitro [PDF]
BACKGROUND The leishmaniases are complex neglected diseases caused by protozoan parasites of the genus Leishmania. Leishmania braziliensis is the main etiological agent of cutaneous leishmaniasis in the New World. In recent studies, genomic changes such
Nathalia Ballesteros +4 more
doaj +1 more source
An outbreak of human Leishmania (Viannia) braziliensis infection [PDF]
The occurrence of acute cutaneous leishmaniasis among inhabitants of 10 farms within 10 Km of the hamlet of Corte de Pedra, Bahia, Brazil was studied prospectively from 1984-1989. A mean population of 1,056 inhabitants living in 146 houses were visited every 6 months and the number of skin ulcers recorded.
França, F. +12 more
openaire +5 more sources
Dicentrine, an aporphine alkaloid, exhibits potent in vitro antileishmanial activity against Leishmania species with high selectivity and low macrophage cytotoxicity. Mechanistic studies reveal that the compound triggers parasite death possibly by inducing mitochondrial membrane disruption and oxidative stress.
Camila S. de Freitas +9 more
wiley +1 more source
Clonagem e expressão da enzina tripanotiona redutase de Leishmania braziliensis e atividade leishmanicida de chalconas [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Programa de Pós-graduação em Biotecnologia, Florianópolis, 2011O presente estudo teve por objetivo avaliar atividade leishmanicida in vitro de chalconas trimetoxiladas contra formas ...
Nunes, Rebeca Körting
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