Results 91 to 100 of about 15,890 (220)

Identification of Serine Proteases from Leishmania braziliensis

Zeitschrift für Naturforschung C, 2007
Leishmania (V.) braziliensis is one of the most important ethiologic agents of the two distinct forms of American tegumentary leishmaniasis (cutaneous and mucosal). The drugs of choice used in leishmaniasis therapy are significantly toxic, expensive and are associated with frequent refractory infections.
Herbert L M, Guedes, João M Neto, Rezende, Mayra A, Fonseca, Cristiane M C, Salles, Bartira, Rossi-Bergmann, Salvatore Giovanni, De-Simone   +5 more
openaire   +2 more sources

Achievement of constitutive fluorescent pLEXSY-egfp Leishmania braziliensis and its application as an alternative method for drug screening in vitro

Memorias do Instituto Oswaldo Cruz
BACKGROUND Gene reporter-fluorescent cells have emerged as alternative method for drug screening. OBJECTIVE Achievement of constitutive expression of fluorescent protein GFP by Leishmania braziliensis as alternative method for drug screening. METHODS
Matheus Silva e Bastos, Luciana Ângelo de Souza, Thiago Souza Onofre, Abelardo Silva Júnior, Márcia Rogéria de Almeida, Gustavo Costa Bressan, Juliana Lopes Rangel Fietto   +6 more
doaj   +1 more source

Identification of the HSP70-II gene in Leishmania braziliensis HSP70 locus: genomic organization and UTRs characterization

Parasites & Vectors, 2011
Background The heat stress suffered by Leishmania sp during its digenetic life-cycle is a key trigger for its stage differentiation. In Leishmania subgenera two classes of HSP70 genes differing in their 3' UTR were described.
Puerta Concepción J, Requena José M, Ramírez César A   +2 more
doaj   +1 more source

Tilting the balance between RNA interference and replication eradicates Leishmania RNA virus 1 and mitigates the inflammatory response. [PDF]

, 2016
Many Leishmania (Viannia) parasites harbor the double-stranded RNA virus Leishmania RNA virus 1 (LRV1), which has been associated with increased disease severity in animal models and humans and with drug treatment failures in humans.
Akopyants, N.S., Beverley, S.M., Brettmann, E.A., Fasel, N., Hickerson, S.M., Kuhlmann, F.M., Lye, L.F., Oschwald, D.M., Owens, K.L., Ronet, C., Shaik, J.S., Zangger, H.   +11 more
core   +2 more sources

Résultats préliminaires en faveur de l'existence d'un antigène majeur de surface, spécifique de LEISHMANIA BRAZILIENSIS BRAZILIENSIS [PDF]

, 1986
L'Etude comparative des antigènes de surface de 10 souches boliviennes de référence de la sous-espèce L. B. Braziliensis a permis de mettre en évidence une grande homogénéité au sein de ce groupe.
Brenière, Simone Frédérique, Desjeux, P., Le Pont, François, Legrand, Dominique, Prina, Eric   +4 more
core  

Dogs as Reservoirs forLeishmania braziliensis

Emerging Infectious Diseases, 2011
To the Editor: I have read the review by Sousa and Pearson (1), which provides a fascinating historical account of the Great Drought and the smallpox epidemic of the 1870s and their association with the emergence of cutaneous leishmaniasis in Ceara, Brazil.
openaire   +2 more sources

Attempts using cryotherapy to achieve more rapid healing in patients with cutaneous leishmaniasis due to L. braziliensis braziliensis

Revista da Sociedade Brasileira de Medicina Tropical, 1983
The use of cryotherapy as an adjunct to systemic antimonial therapy (Clucantime) was studied in 17 patients with a total of23 skin lesions of leishmaniasis in an area where L. braziliensis braziliensis is the species in circulation.
Elmer Alejandro Llanos Cuentas, Philip Davis Marsden, Douglas Torre, Air Colombo Barreto   +3 more
doaj  

Capacidad infectiva de promastigotes en fase estacionaria de leishmania (viannia) braziliensis y leishmania (viannia) peruviana, en línea celular dh82

Revista Peruana de Medicina Experimental y Salud Pública
Objetivos. Determinar la capacidad infectiva de los promastigotes de Leishmania (V.) peruviana y Leishmania (V.) braziliensis en la línea celular macrófago-monocítica de Canis familiaris DH82. Materiales y métodos.
Karen Daphne Calvay-Sánchez, Nyshon Máximo Rojas-Palomino, Aidé Clorinda Sandoval-Juarez, Alberto Cisneros-Tarmeño, Cristian Obregón-Cahuaya, Gloria Sonia Minaya-Gómez   +5 more
doaj   +2 more sources

Leishmania braziliensis: Strain-Specific Modulation of Phagosome Maturation

Frontiers in Cellular and Infection Microbiology, 2019
Leishmania (Viannia) braziliensis is responsible for the largest number of American tegumentary leishmaniasis (ATL) in Brazil. ATL can present several clinical forms including typical (TL) and atypical (AL) cutaneous and mucocutaneous (ML) lesions.
Tamara da Silva Vieira, Tamara da Silva Vieira, Guillermo Arango Duque, Kévin Ory, Kévin Ory, Celia Maria Gontijo, Rodrigo Pedro Soares, Albert Descoteaux   +7 more
doaj   +1 more source

Sequence analysis of the 3-untranslated region of HSP70 (type I) genes in the genus Leishmania: Its usefulness as a molecular marker for species identification [PDF]

, 2015
Background: The Leishmaniases are a group of clinically diverse diseases caused by parasites of the genus Leishmania. To distinguish between species is crucial for correct diagnosis and prognosis as well as for treatment decisions.
Cañavate, Carmen, Chicharro, Carmen, García, Lineth, Parrado, Rudy, Puerta, Concepción J., Requena, José María   +5 more
core   +1 more source