The immunobiology of Leishmania braziliensis infection [PDF]
Leishmaniases are a group of diseases caused by protozoa of the genus Leishmania that affect millions of people worldwide. These diseases are caused by distinct Leishmania species, of which L.
Camila I de Oliveira, Claudia Brodskyn
exaly +5 more sources
Persistent Infections by Leishmania (Viannia) braziliensis [PDF]
Here we review the phenomenon of persistency in Leishmania (Viannia) braziliensis infections. In other Leishmania species where appropriate animal models exist, considerable advances in the understanding of basic immunologic mechanisms of persistency ...
José Luis Ramírez, Palmira Guevara
doaj +4 more sources
Protection and Pathology in Leishmania braziliensis Infection. [PDF]
Leishmania killing is mediated by IFN-γ-activated macrophages, but IFN-γ production and macrophage activation are insufficient to control L. braziliensis infection. In American tegumentary leishmaniasis (ATL), pathology results from an exaggerated inflammatory response.
Carvalho AM, Bacellar O, Carvalho EM.
europepmc +4 more sources
Experimental canine mucocutaneous leishmaniasis (Leishmania braziliensis braziliensis) [PDF]
Four mongrel dogs were intradermically inoculated with 3 x 10**6 Leishmania braziliensis braziliensis promastigotes. Three out of the four animals developed cutaneous lesions respectively 4, 7, and 8 months after. The fourth dog did not develop lesion at the inoculation site, but a mucosal ulcer was seen 16 months after the inoculum.
Pirmez, Claude +2 more
openaire +5 more sources
Dogs Harbor Leishmania braziliensis and Participate in the Transmission Cycle of Human Tegumentary Leishmaniasis [PDF]
Dogs play an important role in transmission of Leishmania infantum, but epidemiologic and clinical studies of canine tegumentary leishmaniasis (CTL) are scarce.
Jamile Lago +9 more
doaj +2 more sources
Histone post-translational modifications of Leishmania braziliensis. [PDF]
Histone post-translational modifications (hPTMs) constitute an epigenetic mechanism that plays a fundamental role in the regulation of gene expression in eukaryotic cells. In trypanosomatid parasites, such as Trypanosoma brucei, T. cruzi and Leishmania spp., gene regulation occurs mainly at the post-transcriptional level.
de Almeida RF +3 more
europepmc +4 more sources
Identification of Serine Proteases from Leishmania braziliensis
Leishmania (V.) braziliensis is one of the most important ethiologic agents of the two distinct forms of American tegumentary leishmaniasis (cutaneous and mucosal). The drugs of choice used in leishmaniasis therapy are significantly toxic, expensive and are associated with frequent refractory infections.
Salvatore Giovanni De-Simone +1 more
exaly +3 more sources
Extreme inbreeding in Leishmania braziliensis [PDF]
Leishmania species of the subgenus Viannia and especially Leishmania braziliensis are responsible for a large proportion of New World leishmaniasis cases.
Rougeron, V. +11 more
openaire +6 more sources
Leishmania braziliensis braziliensis infection of the nipple. [PDF]
3 observations de cette lesion rare: au niveau du mamelon chez un homme de 37 ans, en plusieurs localisations chez une jeune femme allaitant, y compris un mamelon, et au niveau de la levre chez le nourrisson de 3 mois. Excision de granulomes (histologiquement benins).
P D, Marsden +7 more
openaire +2 more sources
The Role of Nitric Oxide and Reactive Oxygen Species in the Killing of Leishmania braziliensis by Monocytes from Patients with Cutaneous Leishmaniasis. [PDF]
Human cutaneous leishmaniasis (CL) caused by Leishmania braziliensis, presents an exaggerated Th1 response that is associated with ulcer development. Macrophages are the primary cells infected by Leishmania parasites and both reactive oxygen species (ROS)
Pedro Paulo Carneiro +5 more
doaj +1 more source

