Results 1 to 10 of about 6,816 (177)
Experimental transmission of Leishmania (Leishmania) amazonensis to immunosuppressed mice through the bite of Lutzomyia longipalpis (Diptera: Psychodidae) results in cutaneous leishmaniasis [PDF]
Revista do Instituto de Medicina Tropical de São Paulo, 2021 Lutzomyia longipalpis is the natural vector of Leishmania (Leishmania) infantum, but it is also permissive for several Leishmania species that are related to cutaneous leishmaniasis (CL). Maranhao State (Northeast of Brazil) is endemic for CL and has the
Rosa Cristina Ribeiro da Silva +5 more
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Surface enolase is a virulence factor of Leishmania amazonensis metacyclic promastigotes involved in adhesion to macrophages [PDF]
Frontiers in MicrobiologyWe find that enolase, an evolutionarily conserved and multifunctional protein, is displayed on the cell surface of Leishmania amazonensis parasites in a developmentally regulated manner, associated with infectivity.
Franciane dos Santos Alves +7 more
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Frontiers in Immunology, 2023 In this study we explored the previously established leishmanicidal activity of a complementary set of 24 imidazolium salts (IS), 1-hexadecylimidazole (C16Im) and 1-hexadecylpyridinium chloride (C16PyrCl) against Leishmania (Leishmania) amazonensis and ...
Fernanda Giesel Baldissera +20 more
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Frontiers in Pharmacology, 2022 Leishmaniasis are endemic diseases caused by different species of intracellular parasites of the genus Leishmania. Due to the high toxicity and drug resistance of current antileishmanial drugs, it is necessary to identify new and more effective drugs ...
Tatiana Barbosa dos Santos Magalhães +13 more
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Innate Resistance to Leishmania amazonensis Infection in Rat Is Dependent on NOS2
Frontiers in Microbiology, 2021 Leishmania infection causes diverse clinical manifestations in humans. The disease outcome is complicated by the combination of many host and parasite factors.
Yun-Fu Chen +11 more
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Ethanolic extract of Croton blanchetianus Ball induces mitochondrial defects in Leishmania amazonensis promastigotes [PDF]
Anais da Academia Brasileira de Ciências, 2020 Leishmaniasis is a neglected disease caused by Leishmania. Chemotherapy remains the mainstay for leishmaniasis control; however, available drugs fail to provide a parasitological cure, and are associated with high toxicity. Natural products are promising
KATILY L.G. PEREIRA +8 more
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Frontiers in Cellular and Infection Microbiology, 2020 Leishmaniasis is an anthropozoonotic disease, and dogs are considered the main urban reservoir of the parasite. Macrophages, the target cells of Leishmania sp., play an important role during infection.
Natalia Rocha Nadaes +11 more
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Revista da Sociedade Brasileira de Medicina Tropical, 2009 As leishmanioses são zoonoses endêmicas em Mato Grosso do Sul e têm por agentes etiológicos nessa região Leishmania (Leishmania) chagasi, Leishmania (Leishmania) amazonensis e Leishmania (Viannia) braziliensis.
Manoel Sebastião da Costa Lima Junior +5 more
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Revista da Sociedade Brasileira de Medicina Tropical, 2007 New therapeutic alternatives against leishmaniasis remain a priority. The activity of azithromycin against Leishmania (Leishmania) major has been previously demonstrated.
Ángel Sinagra +5 more
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Experimental infection and transmission of Leishmania by Lutzomyia cruzi (Diptera: Psychodidae): Aspects of the ecology of parasite-vector interactions. [PDF]
PLoS Neglected Tropical Diseases, 2017 Several parameters should be addressed before incriminating a vector for Leishmania transmission. Those may include its ability to become infected by the same Leishmania species found in humans, the degree of attractiveness for reservoirs and humans and ...
Everton Falcão de Oliveira +7 more
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