Results 21 to 30 of about 6,816 (177)

Transcriptional responses of Leishmania (Leishmania) amazonensis in the presence of trivalent sodium stibogluconate. [PDF]

Parasit Vectors, 2019
Au cours de la dernière décennie, la résistance aux antimoniaux est devenue un problème grave en raison de l'émergence de souches pharmacorésistantes. Par conséquent, il est essentiel de comprendre les mécanismes utilisés par les parasites Leishmania pour survivre sous la pression des médicaments, en particulier pour les espèces d'importance médico ...
Patino LH, Muskus C, Ramírez JD.
europepmc   +5 more sources

Role of Leishmania (Leishmania) amazonensis amastigote glycosphingolipids in macrophage infectivity [PDF]

Brazilian Journal of Medical and Biological Research, 2007
The role of glycosphingolipids (GSLs) present in amastigote forms of Leishmania (Leishmania) amazonensis during infection of macrophages was analyzed, with particular emphasis on GSLs presenting the terminal Galpss1-3Galpa disaccharide. Macrophage invasion by L.
Tanaka, Améria Kaori UNIFESP, Gorin, Philip Albert James, Takahashi, Helio Kiyoshi UNIFESP, Straus, Anita Hilda UNIFESP   +3 more
openaire   +6 more sources

Vaccination of C57BL/10 mice against cutaneous leishmaniasis using killed promastigotes of different strains and species of Leishmania Vacinação de camundongos C57BL/10 contra leishmaniose com promastigotas mortas de diferentes cepas e espécies de Leishmania

Revista da Sociedade Brasileira de Medicina Tropical, 2002
Antigenic extracts from five Leishmania stocks were used to vaccinate C57BL/10 mice. The Leishvacin® and PH8 monovalent vaccine yielded the highest IFN-gamma levels in the supernatants of spleen cell culture from vaccinated animals.
Wilson Mayrink, Gilmara Cristina dos Santos, Vicente de Paulo Coelho Peixoto de Toledo, Tânia Mara Pinto Dabés Guimarães, George Luis Lins Machado-Coelho, Odair Genaro, Carlos Alberto da Costa   +6 more
doaj   +1 more source

Leukocyte Behavior in Mesenteric Microcirculation upon Experimental By Leishmania Spp. in BALB/c Mice

Iranian Journal of Parasitology, 2021
Background: We aimed to determine the cellular recruitment (leukocyte rolling and adhesion) by which the Leishmania (Viannia) braziliensis, L. (Leishmania) amazonensis, and L. (Leishmania) major species in the mesenteric microcirculation of BALB/c mice.
Herintha Coeto Neitzke-Abreu, Rhuan Carlos Souza Caetano, Kárin Rosi Reinhold-Castro, Manoel Sebastião da Costa Lima-Junior, Wagner José Tenório dos Santos, Gessilda de Alcantara Nogueira de Melo, Roberto Kenji Nakamura Cuman, Sandra Mara Alessi Aristides, Thais Gomes Verzignassi Silveira, Maria Valdrinez Campana Lonardoni   +9 more
doaj  

Leishmania (Leishmania) amazonensis Infection in Mice Treated With FTY720

Transplantation Proceedings, 2010
In transplantation, parasite diseases are transmitted from the donor, or appear as de novo infections, or activate from a dormant insource as a consequence of immunosuppression. Clinical findings have shown that an intact immune system is crucial to prevent recurrence of Leishmania infection.
Lopes, C. T. UNIFESP, De Paula, Daisy Maria Bentes UNIFESP, Cury, P. M., Valero-Lapchik, V. B. UNIFESP, Bueno, V. UNIFESP   +4 more
openaire   +3 more sources

Inhibition of growth of Leishmania mexicana mexicana by Leishmania mexicana amazonensis during "in vitro" co-cultivation Inibição do crescimento de Leishmania mexicana mexicana por Leishmania mexicana amazonensis durante o co-cultivo "in vitro"

Memorias do Instituto Oswaldo Cruz, 1987
Inhibition of one Leishmania subspecies by exometabolites of another subspecies, a phenomenon not previously reported, is suggested by our recent observations in cell cloning experiments with Leishmania mexicana mexicana and Leishmania mexicana ...
Raquel S. Pacheco, Gabriel Grimaldi Júnior, Carlos M. Morel   +2 more
doaj   +1 more source

Synthesis, Leishmanicidal Activity and Theoretical Evaluations of a Series of Substituted bis-2-Hydroxy-1,4-Naphthoquinones

Molecules, 2014
A series of eight substituted bis-2-hydroxy-1,4-naphthoquinone derivatives was synthesized through lawsone condensation with various aromatic and aliphatic aldehydes under mild acidic conditions.
Morgana V. de Araújo, Patricia S. O. de Souza, Aline C. de Queiroz, Carolina B. B. da Matta, Anderson Brandão Leite, Amanda Evelyn da Silva, José A. A. de França, Tania M. S. Silva, Celso A. Camara, Magna S. Alexandre-Moreira   +9 more
doaj   +1 more source

Selective effects of Euterpe oleracea (açai) on Leishmania (Leishmania) amazonensis and Leishmania infantum

Biomedicine & Pharmacotherapy, 2018
Leishmania (Leishmania) amazonensis and Leishmania infantum (=Leishmania chagasi) are protozoa that cause American cutaneous and visceral leishmaniasis, respectively. These diseases show a high incidence in developing countries such as Brazil. The treatments used for leishmaniasis are still limited due to their high cost and toxicity.
Bruno José Martins, Da Silva, José Rogério, Souza-Monteiro, Herve, Rogez, Maria Elena, Crespo-López, Jose Luiz M, Do Nascimento, Edilene O, Silva   +5 more
openaire   +2 more sources

Characterization of an extracellular serine protease ofLeishmania (Leishmania) amazonensis

Parasitology, 2005
A serine protease was purified 942-fold from culture supernatant ofL. amazonensispromastigotes using (NH4)2SO4precipitation followed by affinity chromatography on aprotinin-agarose and continuous elution electrophoresis by Prep Cell, yielding a total recovery of 61%.
R E, Silva-Lopez, M G Pinto, Coelho, S G, De Simone   +2 more
openaire   +2 more sources

Cell migration induced by Leishmania (Leishmania) amazonensis, Leishmania (Leishmania) major and Leishmania (Viannia) braziliensis into the peritoneal cavity of BALB/c mice

Journal of Venomous Animals and Toxins including Tropical Diseases, 2010
In American cutaneous leishmaniasis, the initial infection phase is characterized by recruitment of neutrophils and monocytes. The migration of these cells in response to the presence of Leishmania in the peritoneum of affected animals remains unclear ...
DT Wakimoto, KV Gaspareto, TGV Silveira, MVC Lonardoni, SMA Aristides   +4 more
doaj   +1 more source