Sphingolipid degradation in Leishmania (Leishmania) amazonensis.
PLoS Neglected Tropical Diseases, 2012 BackgroundHuman leishmaniasis is caused by more than 20 Leishmania species and has a wide range of symptoms. Our recent studies have demonstrated the essential role of sphingolipid degradation in the virulence of Leishmania (Leishmania) major, a species ...
Agiesh Balakrishna Pillai +3 more
doaj +4 more sources
Serological reactivity of different antigenic preparations of Leishmania (Leishmania) amazonensis and the Leishmania braziliensis complex Reatividade sorológica frente a diferentes preparações antigênicas de Leishmania (Leishmania) amazonensis e do complexo Leishmania braziliensis [PDF]
Revista da Sociedade Brasileira de Medicina Tropical, 2008 Total antigen from Leishmania (Leishmania) amazonensis and isolates from the Leishmania braziliensis complex, along with their respective antigenic fractions obtained by affinity chromatography on concanavalin-A-Sepharose and jacalin-agarose columns ...
Adriano Gomes-Silva +8 more
doaj +6 more sources
Visceral leishmaniasis caused by Leishmania (Leishmania) amazonensis associated with Hodgkin's lymphoma. [PDF]
Rev Inst Med Trop Sao Paulo, 2022 Visceral leishmaniasis (VL) is mainly caused by Leishmania (Leishmania) donovani and Leishmania (L.) infantum; however, other Leishmania species have been associated with VL. We report a case of a patient simultaneously diagnosed with VL caused by Leishmania (L.) amazonensis and Hodgkin's lymphoma.
Porto VBG +9 more
europepmc +5 more sources
Inhibition of Leishmania (Leishmania) amazonensis growth and infectivity by aureobasidin A [PDF]
Journal of Antimicrobial Chemotherapy, 2007 To study the effect of aureobasidin A, an inhibitor of inositol phosphorylceramide (IPC) synthase, on Leishmania growth and infectivity.Effects of aureobasidin A were determined for: (i) promastigote growth in axenic culture; (ii) promastigote infectivity in macrophage monolayers; (iii) development of footpad lesions in BALB/c mice; (iv ...
Ameria K, Tanaka +3 more
openaire +3 more sources
Experimental treatment with sodium stibogluconate of hamsters infected with Leishmania (Leishmania) chagasi and Leishmania (Leishmania) amazonensis [PDF]
Revista da Sociedade Brasileira de Medicina Tropical, 1999 The present paper reports the experimental treatment of hamsters infected with Leishmania chagasi and Leishmania amazonensis with sodium stibogluconate (20mg/kg/day x 20 days). Only with L.
Elizabeth M. de Figueiredo +2 more
doaj +4 more sources
Leishmania in synanthropic rodents (Rattus rattus): new evidence for the urbanization of Leishmania (Leishmania) amazonensis [PDF]
Revista Brasileira de Parasitologia Veterinária, 2017 Abstract This study aimed to detect parasites from Leishmania genus, to determine the prevalence of anti-Leishmania spp. antibodies, to identify circulating species of the parasite, and to determine epidemiological variables associated with infection in rats caught in urban area of Londrina, Paraná, Brazil.
Caldart, Eloiza Teles +8 more
core +7 more sources
Journal of Venomous Animals and Toxins including Tropical Diseases, 2010 In American cutaneous leishmaniasis, the initial infection phase is characterized by recruitment of neutrophils and monocytes. The migration of these cells in response to the presence of Leishmania in the peritoneum of affected animals remains unclear ...
DT Wakimoto +4 more
doaj +2 more sources
Effect of 3-Carene and the Micellar Formulation on Leishmania (Leishmania) amazonensis. [PDF]
Trop Med Infect Dis, 2023 Leishmaniases are neglected tropical diseases caused by obligate intracellular protozoa of the genus Leishmania. The drugs used in treatment have a high financial cost, a long treatment time, high toxicity, and variable efficacy. 3-Carene (3CR) is a hydrocarbon monoterpene that has shown in vitro activity against some Leishmania species; however, it ...
Silva ARST +10 more
europepmc +4 more sources
Arginase expression modulates nitric oxide production in Leishmania (Leishmania) amazonensis
PLOS ONE, 2017 Arginase is an enzyme that converts L-arginine to urea and L-ornithine, an essential substrate for the polyamine pathway supporting Leishmania (Leishmania) amazonensis replication and its survival in the mammalian host. L-arginine is also the substrate of macrophage nitric oxide synthase 2 (NOS2) to produce nitric oxide (NO) that kills the parasite ...
Stephanie Maia Acuña +6 more
openaire +5 more sources
Activity of alkaloids from Aspidosperma nitidum against Leishmania (Leishmania) amazonensis. [PDF]
Sci Rep, 2022 AbstractThis study evaluated the morphological changes caused by fractions and subfractions, obtained from barks of Aspidosperna nitidum, against L. (L.) amazonensis promastigotes. The ethanolic extract (EE) obtained through the maceration of trunk barks was subjected to an acid–base partition, resulting the neutral (FN) and the alkaloid (FA) fractions,
do Socorro Silva da Veiga A +10 more
europepmc +4 more sources