Results 31 to 40 of about 6,816 (177)

Persistence of Leishmania antigen in C57Bl/6j inbred mice infected with Leishmania (Leishmania) amazonensis [PDF]

open access: yesRevista da Associação Médica Brasileira, 1999
To develop an animal model for studying mucocutaneous leishmaniasis.The hind footpad of C57Bl/6j inbred mice was experimentally infected with 10(7) Leishmania (Leishmania) amazonensis promastigote and the skin was studied through light and electron transmission microscopy and immunohistochemistry (PAP) techniques.There were morphological evidences of ...
Vasconcellos, C.   +2 more
openaire   +4 more sources

In vitro leishmanicidal effect of Yangambin and Epi-yangambin lignans isolated from Ocotea fasciculata (Nees) Mez

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
IntroductionYangambin and epi-yangambin are the main lignans found in Louro-de-Cheiro [Ocotea fasciculata (Nees) Mez], a tree native to the Atlantic forests of northeastern Brazil whose leaves and bark are widely used in folk medicine.
Jéssica Rebouças-Silva   +7 more
doaj   +1 more source

In Vitro and In Vivo Activity of a Palladacycle Complex on Leishmania (Leishmania) amazonensis

open access: yesPLoS Neglected Tropical Diseases, 2012
Antitumor cyclopalladated complexes with low toxicity to laboratory animals have shown leishmanicidal effect. These findings stimulated us to test the leishmanicidal property of one palladacycle compound called DPPE 1.2 on Leishmania (Leishmania) amazonensis, an agent of simple and diffuse forms of cutaneous leishmaniasis in the Amazon region, Brazil ...
Carolina de Siqueira Paladi   +6 more
openaire   +4 more sources

Effects of Brazilian propolis on Leishmania amazonensis [PDF]

open access: yesMemórias do Instituto Oswaldo Cruz, 2007
Leishmaniasis, an endemic parasitosis that leads to chronic cutaneous, mucocutaneous or visceral lesions, is part of those diseases, which still requires improved control tools. Propolis has shown activities against different bacteria, fungi, and parasites.
Ayres, Diana Copi   +2 more
openaire   +4 more sources

Leishmania amazonensis promastigotes in 3D Collagen I culture: an in vitro physiological environment for the study of extracellular matrix and host cell interactions [PDF]

open access: yesPeerJ, 2014
Leishmania amazonensis is the causative agent of American cutaneous leishmaniasis, an important neglected tropical disease. Once Leishmania amazonensis is inoculated into the human host, promastigotes are exposed to the extracellular matrix (ECM) of the ...
Debora B. Petropolis   +5 more
doaj   +2 more sources

Amazonian Phlebovirus (Bunyaviridae) potentiates the infection of Leishmania (Leishmania) amazonensis: Role of the PKR/IFN1/IL-10 axis.

open access: yesPLoS Neglected Tropical Diseases, 2019
BackgroundLeishmania parasites are transmitted to vertebrate hosts by phlebotomine sandflies and, in humans, may cause tegumentary or visceral leishmaniasis.
Carolina Torturella Rath   +11 more
doaj   +1 more source

Cohabitation of Leishmania amazonensis and Coxiella burnetii [PDF]

open access: yesTrends in Microbiology, 1996
Intracellular pathogens customize the composition and function of the vacuoles they occupy, and can arrest or distort vacuolar maturation. In doubly infected cells, vacuoles that contain two different parasites can be used to test for exclusionary mechanisms, for expression of vacuolar phenotypes that permit or restrict fusion, and for the survival of ...
M, Rabinovitch, P S, Veras
openaire   +2 more sources

Immune responses induced by a Leishmania (Leishmania) amazonensis recombinant antigen in mice and lymphocytes from vaccinated subjects

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1997
In the search for Leishmania recombinant antigens that can be used as a vaccine against American Cutaneous Leishmaniasis, we identified a Leishmania (Leishmania) amazonensis recombinant protein of 33 kD (Larp33) which is recognized by antibodies and ...
Ana Paula FERNANDES   +10 more
doaj   +1 more source

Systemic treatment of cutaneous leishmaniasis: A systematic review and meta‐analysis

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
This systematic review and meta‐analysis assessed systemic treatments for cutaneous leishmaniasis across 83 studies and 4603 patients. Treatment efficacies of meglumine antimoniate, miltefosine, azoles, pentamidine, and liposomal amphotericin B varied by region and species. Miltefosine showed consistent evidence across multiple settings.
Maximilian Egg   +10 more
wiley   +1 more source

Therapeutic Effects of Matricaria chamomilla Extract in an Immunosuppressed Mouse Model of Cryptosporidiosis

open access: yesVeterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Chamomile (Matricaria chamomilla) extract significantly reduced oocyst shedding and intestinal lesions in immunosuppressed mice infected with Cryptosporidium parvum, while enhancing antioxidant defences (GPx, TAC). These findings suggest chamomile as a promising phytotherapeutic agent for cryptosporidiosis. ABSTRACT Background Cryptosporidiosis, caused
Kousha Kiani   +3 more
wiley   +1 more source

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