Results 51 to 60 of about 6,626 (173)
Active sesquiterpene lactones against Leishmania amazonensis and Leishmania braziliensis [PDF]
Natural Product Research, 2016 Seventeen sesquiterpene lactones (SLs) isolated from five species of the tribe Vernonieae were evaluated for their in vitro activity against promastigotes of Leishmania amazonensis and Leishmania braziliensis. Additionally, a quantitative structure activity relationship has been made, since all these natural compounds were found to have potent to mild ...
A Sosa +7 more
openaire +3 more sources
International Wound Journal, Volume 23, Issue 6, June 2026.ABSTRACT Chronic wounds, exacerbated by infection, aging, diabetes, and oxidative stress, remain a significant challenge in clinical management and impose a substantial burden on healthcare systems. This study presents oregano‐derived plasma polymers (OPP) as a multifunctional surface coating for advanced wound healing applications.
Jesus Romo‐Rico +7 more
wiley +1 more source
Memorias do Instituto Oswaldo Cruz, 2007 The characterization of expressed sequence tags (ESTs) generated from a cDNA library of Leishmania (Leishmania) amazonensis amastigotes is described. The sequencing of 93 clones generated new L. (L.) amazonensis ESTs from which 32% are not related to any
Luciana Girotto Gentil +4 more
doaj +1 more source
Medical and Veterinary Entomology, Volume 40, Issue 2, Page 246-259, June 2026.This study was to describe the composition of sand fly fauna, detect potential vectors of Leishmania spp. in the Tinguá district, an ATL endemic, Rio de Janeiro, Brazil. Seven species of vectorial importance in the epidemiological cycle of leishmaniasis was observed: Nyssomyia intermedia, Migonemyia migonei, Pintomyia fischeri, Psychodopygus hirsutus ...
Antônio L. F. Santana +9 more
wiley +1 more source
Leishmania amazonensis Infection in Nude Mice.
Experimental Animals, 1999 Leishmania amazonensis is an intracellular protozoan parasite of macrophages. Cutaneous leishmaniasis in an immunocompetent host begins as papules or nodules followed by ulceration at the site of promastigote inoculation. In this study, the pathological changes of cutaneous leishmaniasis lesions in T cell deficient nude mice were examined.
TERABE, Masaki +5 more
openaire +3 more sources
Leishmania-Induced Dendritic Cell Migration and Its Potential Contribution to Parasite Dissemination
Microorganisms, 2021 Leishmania, an intracellular parasite species, causes lesions on the skin and in the mucosa and internal organs. The dissemination of infected host cells containing Leishmania is crucial to parasite survival and the establishment of infection.
Amanda Rebouças +10 more
doaj +1 more source
Arginase expression modulates nitric oxide production in Leishmania (Leishmania) amazonensis. [PDF]
PLoS One, 2017 Arginase is an enzyme that converts L-arginine to urea and L-ornithine, an essential substrate for the polyamine pathway supporting Leishmania (Leishmania) amazonensis replication and its survival in the mammalian host. L-arginine is also the substrate of macrophage nitric oxide synthase 2 (NOS2) to produce nitric oxide (NO) that kills the parasite ...
Acuña SM +6 more
europepmc +5 more sources
Zoonoses and Public Health, Volume 73, Issue 4, Page 314-325, June 2026.ABSTRACT Introduction Canine Leishmaniasis is a vector‐borne zoonotic disease caused by several species of protozoa of the genus Leishmania. In the state of Rio de Janeiro (RJ), Leishmania braziliensis is the most prevalent species causing tegumentary leishmaniasis (TL) and Leishmania infantum is the main causative agent of visceral leishmaniasis (VL).
Luciana de Freitas Campos Miranda +10 more
wiley +1 more source
Miltefosine induces programmed cell death in Leishmania amazonensis promastigotes
Memorias do Instituto Oswaldo Cruz, 2011 In the current study, we evaluated the mechanism of action of miltefosine, which is the first effective and safe oral treatment for visceral leishmaniasis, in Leishmania amazonensis promastigotes.
Fernanda de Aquino Marinho +7 more
doaj +1 more source
Fusion between Leishmania amazonensis and Leishmania major parasitophorous vacuoles: live imaging of coinfected macrophages. [PDF]
PLoS Neglected Tropical Diseases, 2010 Protozoan parasites of the genus Leishmania alternate between flagellated, elongated extracellular promastigotes found in insect vectors, and round-shaped amastigotes enclosed in phagolysosome-like Parasitophorous Vacuoles (PVs) of infected mammalian ...
Fernando Real +2 more
doaj +1 more source