Results 71 to 80 of about 10,324 (216)

Leishmania isoenzyme polymorphisms in Ecuador: Relationships with geographic distribution and clinical presentation

, 2006
Background: Determinants of the clinical presentation of the leishmaniases are poorly understood but Leishmania species and strain differences are important.
Cooper Philip J, Masataka Korenaga, Marco Jorge D, Korenaga, Masataka, Rodrigo X Armijos, Hirotomo Kato, Paola A Barroso, Kato Hirotomo, Korenaga, M, Gomez, EA, Calvopina Manuel, Kato, Hirotomo, Hiroshi Uezato, Barroso, Paola A., Armijos, Rodrigo X., Cooper, PJ, Yoshihisa Hashiguchi, Shigeo Nonaka, Nonaka Shigeo, Gomez Eduardo A, Manuel Calvopina, Marco, Jorge D., Kato, H, Barroso Paola A, Mimori, Tatsuyuki, Armijos, RX, Hashiguchi, Y, Nonaka, Shigeo, Eduardo A Gomez, Calvopina, M, Marco, JD, Korenaga Masataka, Tatsuyuki Mimori, Uezato, H, Jorge D Marco, Gomez, Eduardo A., Calvopina, Manuel, Mimori Tatsuyuki, Manuel Calvopina, Uezato Hiroshi, Cooper, Philip J., Hashiguchi, Yoshihisa, Mimori, T, Philip J Cooper, Nonaka, S, Uezato, Hiroshi, Armijos Rodrigo X, Barroso, PA, Hashiguchi Yoshihisa   +48 more
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Miltefosine induces programmed cell death in Leishmania amazonensis promastigotes

Memorias do Instituto Oswaldo Cruz, 2011
In the current study, we evaluated the mechanism of action of miltefosine, which is the first effective and safe oral treatment for visceral leishmaniasis, in Leishmania amazonensis promastigotes.
Fernanda de Aquino Marinho, Keyla Cristiny da Silva Gonçalves, Selma Soares de Oliveira, Ana-Carolina de Siqueira Couto de Oliveira, Maria Bellio, Claudia Masini d'Avila-Levy, André Luis Souza dos Santos, Marta Helena Branquinha   +7 more
doaj   +1 more source

Fusion between Leishmania amazonensis and Leishmania major parasitophorous vacuoles: live imaging of coinfected macrophages. [PDF]

PLoS Neglected Tropical Diseases, 2010
Protozoan parasites of the genus Leishmania alternate between flagellated, elongated extracellular promastigotes found in insect vectors, and round-shaped amastigotes enclosed in phagolysosome-like Parasitophorous Vacuoles (PVs) of infected mammalian ...
Fernando Real, Renato A Mortara, Michel Rabinovitch   +2 more
doaj   +1 more source

Exploring the Role of the MAPK Signalling Pathway in Dog Immunity: From Cancer to Parasitic Diseases

Parasite Immunology, Volume 48, Issue 5, May 2026.
ABSTRACT Mitogen‐activated protein kinases (MAPKs) are intracellular signalling proteins that modulate several cellular processes, such as proliferation, cytokine production and survival. Like humans, dogs may exhibit changes in MAPK signalling under pathological conditions.
Francini Neves Ribeiro, Fernanda Nazaré Morgado, Renato Porrozzi   +2 more
wiley   +1 more source

Metabolomics to unveil and understand phenotypic diversity between pathogen populations [PDF]

, 2010
Visceral leishmaniasis is caused by a parasite called Leishmania donovani, which every year infects about half a million people and claims several thousand lives. Existing treatments are now becoming less effective due to the emergence of drug resistance.
Breitling, Rainer,, Brunker, Kirstyn, Jean-Claude Dujardin, Breitling Rainer, Dujardin, Jean-Claude, Dujardin, Jean Claude, Scheltema, R.A., Coombs, Graham H.,, Rijal, Suman,, Brunker Kirstyn, Coombs, Graham H, Dujardin, J.-C., Rijal, S., Kirstyn Brunker, Coombs Graham H., Coombs, Graham H., Dujardin, Jean-Claude,, Dujardin Jean-Claude, Watson, David G, Jankevics, Andris,, Jankevics Andris, Saskia Decuypere, Watson, D.G., t'Kindt, R., Kindt, Ruben t’,, Suman Rijal, t'Kindt, Ruben, t'Kindt Ruben, Watson David G., Breitling, Rainer, Brunker, K., Breitling, R., Brunker, Kirstyn,, Scheltema Richard A., Jankevics, A., Richard A Scheltema, Geary, T.G., Rijal Suman, Decuypere, S., Graham H. Coombs, Coombs, G.H., Andris Jankevics, Decuypere, Saskia, Scheltema, Richard A, Scheltema, Richard A., David G. Watson, Watson, David G., Richard A. Scheltema, Rainer Breitling, Decuypere Saskia, Jankevics, Andris, Decuypere, Saskia,, Watson, David G.,, David G Watson, 't Kindt, Ruben, Rijal, Suman, Ruben t'Kindt, Scheltema, Richard A.,, Graham H Coombs   +58 more
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Immunogold labeling and cerium cytochemistry of the enzyme ecto-5'-nucleotidase in promastigote forms of Leishmania species

Memorias do Instituto Oswaldo Cruz, 1993
We have applied both enzyme cytochemistry and immunological labeling techniques to characterize the enzyme 5'-nucleotidase (5'-Nase), at the ultrastructural level, in promastigote forms of four Leishmania species: Leishmania amazonensis, Leishmania ...
Suzana Corte-Real, Renato Porrozzi, Maria de Nazareth Leal de Meirelles   +2 more
doaj   +1 more source

Metalloids: Semi as Metals yet Full of Antimicrobial Potential

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
Metalloids such as boron (B), silicon (Si), germanium (Ge), arsenic (As), antimony (Sb), and tellurium (Te) bridge metals and non‐metals, displaying unique chemical versatility. Recent research highlights their diverse antimicrobial and therapeutic potentials, from natural products to synthetic organic and organometallic molcules, underscoring renewed ...
Kevin Böhm, Muhammad Jawad Nasim, Claus Jacob   +2 more
wiley   +1 more source

Leishmaniasis transmission biology: Role of Promastigote Secretory Gel as a transmission determinant [PDF]

Leishmaniasis is a complex vector-borne disease caused by Leishmania sp. (Kinetoplastida: Trypanosomatidae) and is transmitted by female sand flies (Diptera: Psychodidae).
Martin Sainz de la Maza, O
core   +1 more source

Sand fly captures with Disney traps in area of occurrence of Leishmania (Leishmania) amazonensis in the state of Mato Grosso do Sul, mid-western Brazil Capturas de flebotomíneos com armadilhas de Disney em área de ocorrência de Leishmania (Leishmania) amazonensis no estado de Mato Grosso do Sul, região Centro-Oeste do Brasil

Revista da Sociedade Brasileira de Medicina Tropical, 2010
INTRODUCTION: The work was conducted to study phlebotomine fauna (Diptera: Psychodidae) and aspects of American cutaneous leishmaniasis transmission in a forested area where Leishmania (Leishmania) amazonensis occurs, situated in the municipality of Bela
Maria Elizabeth Cavalheiros Dorval, Tulia Peixoto Alves, Geucira Cristaldo, Hilda Carlos da Rocha, Murilo Andrade Alves, Elisa Teruya Oshiro, Alessandra Gutierrez de Oliveira, Reginaldo Peçanha Brazil, Eunice Aparecida Bianchi Galati, Rivaldo Venancio da Cunha   +9 more
doaj   +1 more source

Leishmania Extracellular Vesicles as a Preventive Vaccine Platform Against Leishmaniasis

Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
The potential of Leishmania‐derived extracellular vesicles (EVs) as a vaccine platform was investigated, emphasizing an affordable, GMP‐compliant production and purification method. Immunization with EV vaccines, either unadjuvanted or combined with α‐galactosylceramide (αGC), induced robust humoral and cellular immune responses, conferring protection ...
Ismail Cem Yilmaz, Ibrahim Tokmak, Muzaffer Yildirim, Tugce Canavar Yildirim, Elif Sena Ozkoc, Irem Evcili, Emre Mert Ipekoglu, İhsan Cihan Ayanoglu, Emre Dunuroglu, Dicle Caliskan, Harun Onler, Zeynep Arzum, Ceren Ulker, Olcay Mert, Ridvan Orkut, Ibrahim Oguzhan Tarman, Ulku Guler, Bekir Salih, Volkan Yazar, Gokcen Ozgun, Serap Birincioglu, Ahmet Ozbilgin, Bilgi Gungor, Ihsan Gursel, Mayda Gursel   +24 more
wiley   +1 more source