Results 61 to 70 of about 6,626 (173)
Structural basis of secreted acid phosphatase polymerization in the Leishmania parasite
Abstract Enzymes that assemble into filaments typically transition between protomeric and polymeric states in response to cellular conditions. In contrast, the secreted acid phosphatase (SAP) of Leishmania, one of the most abundant extracellular glycoproteins produced by the parasite and regarded as a major virulence factor in the neglected tropical ...
Priyanka Bose +4 more
wiley +1 more source
We have applied both enzyme cytochemistry and immunological labeling techniques to characterize the enzyme 5'-nucleotidase (5'-Nase), at the ultrastructural level, in promastigote forms of four Leishmania species: Leishmania amazonensis, Leishmania ...
Suzana Corte-Real +2 more
doaj +1 more source
Nano‐encapsulated Cinnamomum cassia essential oil (nano‐CC‐EO) showed in vitro antifungal activity against fluconazole‐resistant Nakaseomyces glabratus and Pichia kudriavzevii clinical isolates. Checkerboard assays revealed synergistic or additive interactions between nano‐CC‐EO and fluconazole in several isolates, without evidence of antagonism. These
Mehrdad Seifi +5 more
wiley +1 more source
INTRODUCTION: The work was conducted to study phlebotomine fauna (Diptera: Psychodidae) and aspects of American cutaneous leishmaniasis transmission in a forested area where Leishmania (Leishmania) amazonensis occurs, situated in the municipality of Bela
Maria Elizabeth Cavalheiros Dorval +9 more
doaj +1 more source
Tegumentary Leishmaniasis Associated With Immune Reconstitution in an HIV Patient—A Case Report
ABSTRACT HIV‐associated Immune Reconstitution Inflammatory Syndrome (IRIS) may significantly alter the immunopathological presentation of American Tegumentary Leishmaniasis (ATL), occasionally causing paradoxical clinical exacerbations. We report the long‐term follow‐up of a 39‐year‐old female coinfected with HIV and disseminated mucocutaneous ...
Marilia Brasil Xavier +9 more
wiley +1 more source
Exploring the Role of the MAPK Signalling Pathway in Dog Immunity: From Cancer to Parasitic Diseases
ABSTRACT Mitogen‐activated protein kinases (MAPKs) are intracellular signalling proteins that modulate several cellular processes, such as proliferation, cytokine production and survival. Like humans, dogs may exhibit changes in MAPK signalling under pathological conditions.
Francini Neves Ribeiro +2 more
wiley +1 more source
Cutaneous leishmaniases are anthropozoonoses that involve many species of Leishmania and a wide variety of wild mammalian hosts, thus presenting high importance to public health.
AI Souza +3 more
doaj +1 more source
Metalloids: Semi as Metals yet Full of Antimicrobial Potential
Metalloids such as boron (B), silicon (Si), germanium (Ge), arsenic (As), antimony (Sb), and tellurium (Te) bridge metals and non‐metals, displaying unique chemical versatility. Recent research highlights their diverse antimicrobial and therapeutic potentials, from natural products to synthetic organic and organometallic molcules, underscoring renewed ...
Kevin Böhm +2 more
wiley +1 more source
INTRODUCTION: Leishmania species cause skin, mucosal, and disseminated lesions. We studied the effects of three Leishmania species on ileal morphology in mice.
Amanda Gubert Alves dos Santos +5 more
doaj +1 more source
The outcome of Leishmania infections is determined by both the parasite species and the host genetic makeup. While much has been learned regarding immune responses to this parasite, our knowledge on parasite-derived factors is limited.
Reynolds K. B. Brobey +3 more
doaj +1 more source

