Results 181 to 190 of about 11,235 (212)
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Ultrastructural and cytochemical identification of megasome in Leishmania (Leishmania) chagasi

Parasitology Research, 2004
The present work showed the presence of a megasome in Leishmania (Leishmania) chagasi amastigotes. Transmission electron microscopy analysis of ultrathin serial sections and three-dimensional reconstruction allowed visualization of large structures in amastigote forms of L.
Sanny O, Alberio   +5 more
openaire   +2 more sources

Antileishmanial Activity of Azitahromycin Against Leishmania (Leishmania) amazonensis, Leishmania (Viannia) braziliensis, and Leishmania (Leishmania) chagasi

The American Journal of Tropical Medicine and Hygiene, 2008
Azithromycin, an azalide antibiotic, is highly concentrated within different phagocytic cells, especially macrophages. The potential antileishmanial activity of azithromycin against three species of Leishmania from the New World was assessed using in vitro models.
Fernanda, de Oliveira-Silva   +2 more
openaire   +2 more sources

Asymptomatic human carriers of Leishmania chagasi.

The American journal of tropical medicine and hygiene, 2002
In Brazil, programs based on elimination of infected dogs have not curtailed the spread of visceral leishmaniasis (VL), suggesting that other reservoirs of infection exist. Persons with active VL can infect the sand fly vector, but in endemic areas, persons with asymptomatic infections, whose infectivity to sand flies is unknown, are far more numerous.
Carlos H N, Costa   +12 more
openaire   +2 more sources

Detection of Leishmania (L.) chagasi in canine skin

Veterinary Parasitology, 2011
Canine visceral leishmaniasis (CVL) is caused by a protozoa parasite of the specie Leishmania (L.) chagasi endemic for humans and dogs in many regions of Brazil. The purpose of the present study was the detection of (L.) chagasi in canine skin tissues from three different groups of clinical signs: asymptomatic, oligosymptomatic and polysymptomatic ...
de Queiroz, N. M. G. P.   +5 more
openaire   +3 more sources

Apoptosis of Leishmania (Leishmania) chagasi amastigotes in hamsters infected with visceral leishmaniasis

International Journal for Parasitology, 2004
Apoptosis in amastigotes from hamsters infected with visceral leishmaniasis was absent 30-day post-infection but appeared 90-day post-infection in the liver and spleen, as analysed using the TUNEL method. Necrosis was not present in these tissues and the nuclei of macrophages harbouring apoptotic amastigotes were preserved. Amastigote DNA fragmentation
José A L, Lindoso   +2 more
openaire   +2 more sources

Diffuse Intralobular Liver Fibrosis in Dogs Naturally Infected with Leishmania (Leishmania) chagasi

The American Journal of Tropical Medicine and Hygiene, 2008
The aim of this study was to evaluate the diffuse intralobular fibrosis in dogs naturally infected with Leishmania (Leishmania) chagasi. One hundred five infected animals with positive serologic tests for Leishmania were divided into two clinical groups: 69 symptomatic animals and 36 asymptomatic.
Ferdinan, Melo   +8 more
openaire   +2 more sources

Familial Aggregation of Leishmania chagasi Infection in Northeastern Brazil

The American Journal of Tropical Medicine and Hygiene, 1995
A sample of 1,604 individuals belonging to 243 nuclear families from an endemic area of visceral leishmaniasis (Jacobina, Bahia State, Brazil) was studied to disclose the intrafamilial pattern of infection. Significant father to offspring, mother to offspring, and sibling to sibling associations, in contrast a with nonsignificant father to mother ...
P H, Cabello   +3 more
openaire   +2 more sources

Identification of Leishmania chagasi Antigens Recognized by Human Lymphocytes

Journal of Infectious Diseases, 1995
Preparative SDS-PAGE followed by electroelution was used to separate proteins of Leishmania chagasi promastigotes into 67 fractions. These fractions were tested for the ability to stimulate proliferation of peripheral blood mononuclear cells from healthy immune donors who were treated previously for visceral leishmaniasis and from nonimmune controls ...
S M, Jeronimo   +6 more
openaire   +2 more sources

Cleavable complex formation in Leishmania chagasi treated with anilinoacridines

Molecular and Biochemical Parasitology, 1994
Anilinoacridines have recently been found to possess antiparasitic activity toward Leishmania, Trypanosoma, and Plasmodium species. These compounds have been examined for their ability to generate cleavable complex, the protein-associated DNA lesion characteristic of topoisomerase II involvement, in intact L. chagasi promastigotes.
K A, Werbovetz   +3 more
openaire   +2 more sources

Leishmania (Leishmania) chagasi interactions with Serratia marcescens: Ultrastructural studies, lysis and carbohydrate effects

Experimental Parasitology, 2008
Studies on the lysis of L. chagasi caused by the bacteria Serratia marcescens were carried out. In vitro experiments demonstrated that S. marcescens variant SM 365, a prodigiosin pigment producer, lysed this species of Leishmania but variant DB11, a nonpigmented bacteria, was unable to lyse the parasite.
Caroline S, Moraes   +6 more
openaire   +2 more sources

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