Results 1 to 10 of about 6,846 (239)

The Antileishmanial Potential of C-3 Functionalized Isobenzofuranones against Leishmania (Leishmania) Infantum Chagasi. [PDF]

Molecules, 2015
Leishmaniases are diseases caused by protozoan parasites of the genus Leishmania. Clinically, leishmaniases range from cutaneous to visceral forms, with estimated global incidences of 1.2 and 0.4 million cases per year, respectively. The treatment of these diseases relies on multiple parenteral injections with pentavalent antimonials or amphotericin B.
Pereira WL, de Souza Vasconcellos R, Mariotini-Moura C, Saar Gomes R, Firmino Rde C, da Silva AM, Silva Júnior A, Bressan GC, Almeida MR, Crocco Afonso LC, Teixeira RR, Lopes Rangel Fietto J.   +11 more
europepmc   +9 more sources

Lipophosphoglycan 3 From Binds Heparin With Micromolar Affinity [PDF]

Bioinformatics and Biology Insights, 2018
Leishmania infantum chagasi is an intracellular protozoan parasite responsible for visceral leishmaniasis, a fatal disease in humans. Heparin-binding proteins (HBPs) are proteins that bind to carbohydrates present in glycoproteins or glycolipids ...
Thaís Viana Fialho Martins, Ana Eliza Zeraik, Natália Oliveira Alves, Leandro Licursi de Oliveira, Tiago Antônio de Oliveira Mendes, Ricardo DeMarco, Eduardo de Almeida Marques-da-Silva   +6 more
doaj   +4 more sources

Immucillins Impair Leishmania (L.) infantum chagasi and Leishmania (L.) amazonensis Multiplication In Vitro. [PDF]

PLoS ONE, 2015
Chemotherapy against visceral leishmaniasis is associated with high toxicity and drug resistance. Leishmania parasites are purine auxotrophs that obtain their purines from exogenous sources.
Elisangela Oliveira Freitas, Dirlei Nico, Rong Guan, José Roberto Meyer-Fernandes, Keith Clinch, Gary B Evans, Peter C Tyler, Vern L Schramm, Clarisa B Palatnik-de-Sousa   +8 more
doaj   +6 more sources

First molecular detection of Leishmania (Leishmania) infantum chagasi in a domestic cat (Felis catus) from an urban area in eastern Amazon [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2023
Background: Domestic cats have been implicated as accidental hosts of Leishmania sp. However, in recent years, the recurrent description of new cases in endemic and nonendemic areas draw attention to the potential epidemiological role of cats as ...
Délia Cristina Figueira Aguiar, Daniela de Nazaré dos Santos Nascimento, Dinaiara Fragoso Penner, Brena do Socorro Lima de Castro, Rodrigo Rodrigues Virgolino, Alan Marcel Pamplona Neves, Andrei dos Santos Siqueira, Evonnildo Costa Gonçalves   +7 more
doaj   +2 more sources

A novel A2 allele found in Leishmania (Leishmania) infantum chagasi Novo alelo do gene A2 descrito em Leishmania (Leishmania) infantum chagasi [PDF]

Revista Brasileira de Parasitologia Veterinária, 2011
Visceral leishmaniasis (VL) is a widely spread zoonotic disease. In Brazil the disease is caused by Leishmania (Leishmania) infantum chagasi. Peridomestic sandflies acquire the etiological agent by feeding on blood of infected reservoir animals, such as ...
Trícia Maria Ferreira de Sousa Oliveira, Elton José Rosas de Vasconcelos, Andréa Cristina Higa Nakaghi, Tânia Paula Aquino Defina, Márcia Mariza Gomes Jusi, Cristiane Divan Baldani, Ângela Kaysel Cruz, Rosangela Zacarias Machado   +7 more
doaj   +8 more sources

Infectivity studies of Leishmania (Leishmania) infantum chagasi isolated from non-ulcerated cutaneous leishmaniasis. [PDF]

Rev Inst Med Trop Sao Paulo
ABSTRACT In Honduras, Leishmania (Leishmania) infantum chagasi, the etiological agent of visceral leishmaniasis (VL), is responsible for non-ulcerated cutaneous leishmaniasis (NUCL). We characterized NUCL and VL Honduran strains to understand intraspecies infectivity. Based on in-vitro assays, we aimed to elucidate certain host-parasite interactions in
Araujo Flores GV, Sandoval Pacheco CM, Tomokane TY, Sosa Ochoa WH, Silveira FT, Zúniga C, Pereira Corbett CE, Soares RPP, Passero LFD, Laurenti MD.   +9 more
europepmc   +3 more sources

Diagnóstico molecular e frequência de anticorpos anti-Leishmania infantum chagasi em cães do município de Belém, Pará [PDF]

Pesquisa Veterinária Brasileira, 2014
A leishmaniose visceral é uma enfermidade cujo agente etiológico no Brasil é o protozoário Leishmania infantum chagasi. Os cães são considerados reservatórios urbanos da doença, sendo indicadores da ocorrência de casos humanos.
Katiane Schwanke, Aryane M.M. da Silva, Adlilton Pacheco, Michele Bahia, Fernando T. Silveira, Alessandra Scofield, Gustavo Góes-Cavalcante   +6 more
doaj   +2 more sources

Final comments on an interesting taxonomic dilemma: Leishmania infantum versus Leishmania infantum chagasi [PDF]

Memorias do Instituto Oswaldo Cruz, 2006
: donot forget the law of priorityfl (Dantas-Torres 2006) Πonthe concise review article of Lainson and Rangel (2005)has emerged as the basis of an interesting debate on theaetiological agent of American visceral leishmaniasis, i.e.,the taxonomic dilemma concerning its correct nomen-clature.
Filipe Dantas-Torres
doaj   +4 more sources

Leishmania infantum versus Leishmania chagasi: do not forget the law of priority [PDF]

Memórias do Instituto Oswaldo Cruz, 2006
(Diptera:Psychodidae) and visceral leishmaniasis (VL) in the Ameri-cas, with particular attention to the eco-epidemiology ofdisease in Brazil. In their review, they have discussed withproperty the taxonomic position and origin of the causalagent of the disease.
Filipe Dantas‐Torres
openalex   +6 more sources

Leishmania (infantum) chagasi in canine urinary sediment [PDF]

Revista Brasileira de Parasitologia Veterinária, 2015
Canine visceral leishmaniasis (CVL) is difficult to diagnosis, mainly due to the presence of asymptomatic animals, the diversity of clinical symptoms and the difficulty in obtaining diagnostic evidence of high sensitivity and specificity.
Ivete Lopes de Mendonça, Joilson Ferreira Batista, Leucio Camara Alves   +2 more
doaj   +3 more sources