Results 1 to 10 of about 203 (121)

Immucillins Impair Leishmania (L.) infantum chagasi and Leishmania (L.) amazonensis Multiplication In Vitro [PDF]

PLoS ONE, 2015
Chemotherapy against visceral leishmaniasis is associated with high toxicity and drug resistance. Leishmania parasites are purine auxotrophs that obtain their purines from exogenous sources.
Rong Guan, JOSÉ Roberto Meyer-Fernandes, Keith Clinch   +2 more
exaly   +5 more sources

Characterization of Leishmania (L.) infantum chagasi in visceral leishmaniasis associated with hiv co-infection in Northeastern Brazil [PDF]

Revista do Instituto de Medicina Tropical de São Paulo, 2017
Visceral leishmaniasis, associated with HIV/AIDS coinfection, is becoming a more aggressive disease, complicating an accurate prognosis. A 21-year-old HIV-positive female presenting with clinical features of visceral leishmaniasis was enrolled in this ...
Elaine Cristina Bomfim de Lima, Walter Lins Barbosa Júnior, Maria Edileuza Felinto de Brito, Fábio Lopes de Melo, Sinval Pinto Brandão Filho, Zulma Maria de Medeiros   +5 more
doaj   +4 more sources

Vaccination with L. infantum chagasi nucleosomal histones confers protection against new world cutaneous leishmaniasis caused by Leishmania braziliensis.

PLoS ONE, 2012
BackgroundNucleosomal histones are intracellular proteins that are highly conserved among Leishmania species. After parasite destruction or spontaneous lysis, exposure to these proteins elicits a strong host immune response.
Marcia W Carneiro, Diego M Santos, Kiyoshi F Fukutani, Jorge Clarencio, Jose Carlos Miranda, Claudia Brodskyn, Aldina Barral, Manoel Barral-Netto, Manuel Soto, Camila I de Oliveira   +9 more
doaj   +6 more sources

Lutzomyia longipalpis TGF-β Has a Role in Leishmania infantum chagasi Survival in the Vector

Frontiers in Cellular and Infection Microbiology, 2019
Despite the increasing number of studies concerning insect immunity, Lutzomyia longipalpis immune responses in the presence of Leishmania infantum chagasi infection has not been widely investigated. The few available studies analyzed the role of the Toll
Erich Loza Telleria, Rodrigo De Macedo Couto, Magdalena Jančářová   +2 more
exaly   +3 more sources

In vitro activity of phospholipase A 2 and of peptides from Crotalus durissus terrificus venom against amastigote and promastigote forms of Leishmania (L.) infantum chagasi [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2015
Background American visceral leishmaniasis is caused by the intracellular parasiteLeishmania (L.) infantum chagasi, and transmitted by the sand fly Lutzomyia longipalpis.
Gustavo A. C. Barros, Andreia V. Pereira, Luciana C. Barros, Airton Lourenço Jr, Sueli A. Calvi, Lucilene D. Santos, Benedito Barraviera, Rui Seabra Ferreira Jr   +7 more
doaj   +6 more sources

Hemostatic assessment of dogs associated with hepatic parasite load of Leishmania infantum chagasi

Brazilian Journal of Veterinary Parasitology, 2016
Leishmania infantum chagasi liver parasite load was compared to hemostatic abnormalities, as well as to clinical, laboratorial, and histopathological findings in dogs with visceral leishmaniasis. The liver parasite load of 30 dogs L.
Arleana Do Bom Parto Ferreira De Almeida, Daphine Ariadne Jesus De Paula, Adriane Jorge Mendonça   +2 more
exaly   +3 more sources

Unusual Clinical Manifestations of Leishmania (L.) infantum chagasi in an HIV-coinfected Patient and the Relevance of ITS1-PCR-RFLP: A Case Report

Iranian Journal of Parasitology, 2018
Patients coinfected with Leishmania/HIV can develop atypical forms of visceral leishmaniasis (VL), making it indispensable to identify the etiological agent. We are presenting a postmortemspecie definition by ITS1-PCR-RFLP in a larynx tissue of a patient
De Godoy NATALIA SOUZA DE, Aiello VERA DEMARCHI, de Souza REGINA MAIA, Okay THELMA, Braz LUCIA MARIA ALMEIDA   +4 more
doaj   +2 more sources

Imidazolium salts as an alternative for anti-Leishmania drugs: Oxidative and immunomodulatory activities

Frontiers in Immunology, 2023
In this study we explored the previously established leishmanicidal activity of a complementary set of 24 imidazolium salts (IS), 1-hexadecylimidazole (C16Im) and 1-hexadecylpyridinium chloride (C16PyrCl) against Leishmania (Leishmania) amazonensis and ...
Fernanda Giesel Baldissera, Fernanda Giesel Baldissera, Tiago Fazolo, Tiago Fazolo, Matheus Brasil da Silva, Paulo Cesar de Santana Filho, Vinícius Demétrio da Silva, David Max Rivillo Perez, Joice Sandra Klitzke, Eduardo Giovanni de Oliveira Soares, Luiz Carlos Rodrigues Júnior, Luiz Carlos Rodrigues Júnior, Alessandra Peres, Alessandra Peres, Eliane Dallegrave, Kely Campos Navegantes-Lima, Marta Chagas Monteiro, Henri Stephan Schrekker, Pedro Roosevelt Torres Romão, Pedro Roosevelt Torres Romão, Pedro Roosevelt Torres Romão   +20 more
doaj   +1 more source

Comparative Genomic Analyses of New and Old World Viscerotropic Leishmanine Parasites: Further Insights into the Origins of Visceral Leishmaniasis Agents

Microorganisms, 2022
Visceral leishmaniasis (VL), also known as kala-azar, is an anthropozoonotic disease affecting human populations on five continents. Aetiologic agents belong to the Leishmania (L.) donovani complex.
Fernando Tobias Silveira, Edivaldo Costa Sousa Junior, Rodrigo Vellasco Duarte Silvestre, Thiago Vasconcelos dos Santos, Wilfredo Sosa-Ochoa, Concepción Zúniga Valeriano, Patrícia Karla Santos Ramos, Samir Mansour Moraes Casseb, Luciana Vieira do Rêgo Lima, Marliane Batista Campos, Vania Lucia da Matta, Claudia Maria Gomes, Gabriela V. Araujo Flores, Carmen M. Sandoval Pacheco, Carlos Eduardo Corbett, Márcia Dalastra Laurenti   +15 more
doaj   +1 more source

Susceptibility of Cebus apella monkey (Primates: Cebidae) to experimental Leishmania (L.) infantum chagasi-infection [PDF]

Revista do Instituto de Medicina Tropical de São Paulo, 2011
In Amazonian Brazil, the Cebus apella monkey (Primates: Cebidae) has been associated with the enzootic cycle of Leishmania (V.) shawi, a dermotropic parasite causing American cutaneous leishmaniasis (ACL). It has also been successfully used as animal model for studying cutaneous leishmaniasis.
Carneiro, Liliane Almeida, Silveira, Fernando Tobias, Campos, Marliane Batista, Brígido, Maria do Carmo de Oliveira, Gomes, Claudia Maria C., Corbett, Carlos E.P., Laurenti, Márcia D.   +6 more
openaire   +5 more sources