Results 41 to 50 of about 2,247 (156)

Antiprotozoal action of synthetic cinnamic acid analogs

Revista da Sociedade Brasileira de Medicina Tropical
INTRODUCTION Leishmaniasis, Chagas disease, and malaria cause morbidity globally. The drugs currently used for treatment have limitations. Activity of cinnamic acid analogs against Leishmania spp., Trypanosoma cruzi, and Plasmodium falciparum was ...
Ana Paula de Azevedo dos Santos, Saara Nery Fialho, Daniel Sol Sol de Medeiros, Ana Fidelina Gómez Garay, Jorge Alfonso Ruiz Diaz, Maria Celeste Vega Gómez, Carolina Bioni Garcia Teles, Leonardo de Azevedo Calderon   +7 more
doaj   +1 more source

Experimental infection parameters in Galea spixii (Rodentia: Caviidae) with Leishmania infantum chagasi

Memorias do Instituto Oswaldo Cruz, 2008
In order to better understand the epidemiological transmission network of leishmaniasis, an endemic disease in Northeast Brazil, we investigated the susceptibility of Spix yellow-toothed cavies (Galea spixii) to the Leishmania infantum chagasi parasite ...
Patrícia Batista Barra Medeiros Barbosa, Paula Viviane Sousa de Queiroz, Selma Maria B Jerônimo, Maria de Fátima Freire de Melo Ximenes   +3 more
doaj   +1 more source

Potential vectors of Leishmaniases in the Environmental Protection Area and Tinguá Federal Biological Reserve, Municipality of Nova Iguaçu, Rio de Janeiro, Brazil

Medical and Veterinary Entomology, Volume 40, Issue 2, Page 246-259, June 2026.
This study was to describe the composition of sand fly fauna, detect potential vectors of Leishmania spp. in the Tinguá district, an ATL endemic, Rio de Janeiro, Brazil. Seven species of vectorial importance in the epidemiological cycle of leishmaniasis was observed: Nyssomyia intermedia, Migonemyia migonei, Pintomyia fischeri, Psychodopygus hirsutus ...
Antônio L. F. Santana, Alfredo C. R. Azevedo, Margarete M. S. Afonso, Bruno M. Carvalho, Vanessa R. Vieira, Simone M. Costa, Júlia S. Silva, Thais A. Pereira, Daniela P. Pereira, Maurício L. Vilela   +9 more
wiley   +1 more source

Evaluation of the Cutaneous Immunological Milieu Before and After Treatment With Meglumine Antimoniate in Dogs Naturally Affected by Leishmaniosis due to Leishmania infantum

Veterinary Dermatology, Volume 37, Issue 3, Page 455-463, June 2026.
Background: Canine leishmaniosis (CanL) is a zoonotic disease of variable severity. The typical immune response is driven by an exaggerated humoral immune response. Protective immunity is mediated by pro‐inflammatory cytokines that enhance macrophage leishmanicidal activity. Objective: To evaluate the cutaneous and the systemic immune responses as well
M. Platenik, A. Di Loria, L. Archer, M. Saridomichelakis, A. S. Benvenuto, D. Santoro   +5 more
wiley   +1 more source

Molecular and serological detection of tick-borne pathogens in dogs from an area endemic for Leishmania infantumin Mato Grosso do Sul, Brazil

Revista Brasileira de Parasitologia Veterinária
Tick-borne pathogens affect a wide range of vertebrate hosts. To identify tick-borne pathogens among dogs from Campo Grande, MS, Brazil testing seropositive for Leishmania infantum (syn. L.
Keyla Carstens Marques de Sousa, Marcos Rogério André, Heitor Miraglia Herrera, Gisele Braziliano de Andrade, Marcia Mariza Gomes Jusi, Luciana Ladislau dos Santos, Wanessa Teixeira Gomes Barreto, Rosangela Zacarias Machado, Gilson Pereira de Oliveira   +8 more
doaj   +1 more source

Factors Associated With the Emergence and Spread of Visceral Leishmaniasis in the State of São Paulo, Brazil

Zoonoses and Public Health, Volume 73, Issue 4, Page 348-357, June 2026.
ABSTRACT Introduction Visceral leishmaniasis (VL), once considered a rural disease in Brazil, has progressively urbanised, particularly in the state of São Paulo (SSP), where the first urban cases emerged after the detection of the vector Lutzomyia longipalpis in 1997.
Vera Lucia Fonseca de Camargo‐Neves, Guilherme Loureiro Werneck   +1 more
wiley   +1 more source

Antileishmanial activity and immunomodulatory effect of secosubamolide, a butanolide isolated from Nectandra oppositifolia (Lauraceae)

Journal of Venomous Animals and Toxins including Tropical Diseases
Background: Visceral leishmaniasis is a complex neglected tropical disease caused by Leishmania donovani complex. Its current treatment reveals strong limitations, especially high toxicity.
Thais A. da Costa-Silva, Geanne A. Alves Conserva, Andrés J. Galisteo Jr, Andre G. Tempone, João Henrique G. Lago   +4 more
doaj   +1 more source

Ecological Perspectives on Leishmaniasis Parasitism Patterns: Evidence of Possible Alternative Vectors for <i>Leishmania</i> (<i>Leishmania</i>) <i>infantum</i> (syn. <i>L. chagasi</i>) and <i>Leishmania</i> (<i>Viannia</i>) <i>braziliensis</i> in Piauí, Brazil. [PDF]

Pathogens
Leishmaniasis is difficult to control due to clinical and vector diversity associated with the complex life cycle of Leishmania parasites, which are transmitted by sandflies. This study investigated the presence of Leishmania DNA in sandfly vectors, their blood meal sources, and their distribution in relation to environmental and climatic variables in ...
de Sousa RLT, Araujo-Pereira T, Vasconcelos SA, Freire SM, Lima OB, Dos Santos-Mallet JR, Vilela ML, Vasconcelos VMS, de Andrade EB, Gomes R, Teixeira C, Carvalho BM, Pita-Pereira D, Britto C.   +13 more
europepmc   +3 more sources

The contribution of immune evasive mechanisms to parasite persistence in Visceral Leishmaniasis

Frontiers in Immunology, 2016
Leishmania is a genus of protozoan parasites that give rise to a range of diseases called Leishmaniasis that affects annually an estimated 1.3 million people from 88 countries.
Elisangela Oliveira De Freitas, Fabiana Maria de Souza Leoratti, Célio Geraldo Freire De Lima, Alexandre eMorrot, Daniel eFerreira Feijó   +4 more
doaj   +1 more source

Reduced Leishmania (L.) infantum chagasi parasitic loads in humans exposed to Lutzomyia longipalpis bites in the Amazon region of Brazil [PDF]

Parasitology Open, 2017
SUMMARY We performed a cross-sectional survey in humans to evaluate Lutzomyia longipalpis, i.e. sand fly vector, bite exposure association with Leishmania (Leishmania) infantum chagasi infection in Bujarú municipality, Northern Brazil, an endemic area for visceral leishmaniasis. In recruited individuals, which were stratified by sex and age,
MÁRCIA DALASTRA LAURENTI, LUIS FERNANDO CHAVES, THAÍSE YUMIE TOMOKANE, IBRAHIM ABBASI, ALON WARBURG, FERNANDO TOBIAS SILVEIRA   +5 more
openaire   +1 more source