Results 61 to 70 of about 885 (162)
The contribution of immune evasive mechanisms to parasite persistence in Visceral Leishmaniasis
Leishmania is a genus of protozoan parasites that give rise to a range of diseases called Leishmaniasis that affects annually an estimated 1.3 million people from 88 countries.
Elisangela Oliveira De Freitas +4 more
doaj +1 more source
Abstract Background and Objectives According to the World Health Organization, more than 1 billion people are at risk of leishmaniasis in over 89 countries. Environmental changes such as deforestation, urban expansion and climate change facilitate the spread of sand fly vectors and reservoirs, increasing disease transmission.
Ismael Severino de Lima +14 more
wiley +1 more source
Inhibition of trypsin expression in Lutzomyia longipalpis using RNAi enhances the survival of Leishmania [PDF]
Background Leishmania parasites must overcome several barriers to achieve transmission by their sand fly vectors. One of the earliest threats is exposure to enzymes during blood meal digestion.
Rod J Dillon +17 more
core +1 more source
Sex in Immune Cells and Parasitic Diseases — A Complex Relationship
ABSTRACT Epidemiological studies consistently show that many parasitic diseases affect males more frequently than females. These disparities are multifactorial, arising partly from gender‐specific behaviors that influence exposure risk and health‐seeking practices, especially in low‐ and middle‐income countries. Increasing evidence also highlights that
Barbara Honecker +2 more
wiley +1 more source
Reduced Leishmania (L.) infantum chagasi parasitic loads in humans exposed to Lutzomyia longipalpis bites in the Amazon region of Brazil [PDF]
SUMMARY We performed a cross-sectional survey in humans to evaluate Lutzomyia longipalpis, i.e. sand fly vector, bite exposure association with Leishmania (Leishmania) infantum chagasi infection in Bujarú municipality, Northern Brazil, an endemic area for visceral leishmaniasis. In recruited individuals, which were stratified by sex and age,
MÁRCIA DALASTRA LAURENTI +5 more
openaire +1 more source
Leishmaniasis, caused by Leishmania spp. and transmitted by phlebotomine sand flies, affects almost 1,000,000 people annually across more than 90 countries. In Mexico, growing evidence of locally acquired transmission in northwestern states makes ecoepidemiological work increasingly urgent.
Juan José Ríos Tostado +8 more
wiley +1 more source
Dogs are considered to be the main domestic reservoir associated with the transmission of Leishmania (L.) infantum chagasi to humans in endemic areas of visceral leishmaniasis in America. However, little is known about the role of canines as a source of infection in endemic areas of nonulcerated cutaneous leishmaniasis (NUCL).
Gabriela Beatriz Rodriguez Segura +10 more
openaire +3 more sources
Functional analysis of leishmania cyclopropane fatty acid synthetase [PDF]
The single gene encoding cyclopropane fatty acid synthetase (CFAS) is present in Leishmania infantum, L. mexicana and L. braziliensis but absent from L. major, a causative agent of cutaneous leishmaniasis. In L.
Mottram Jeremy C. +39 more
core +1 more source
Lipophosphoglycan 3 From Binds Heparin With Micromolar Affinity
Leishmania infantum chagasi is an intracellular protozoan parasite responsible for visceral leishmaniasis, a fatal disease in humans. Heparin-binding proteins (HBPs) are proteins that bind to carbohydrates present in glycoproteins or glycolipids ...
Thaís Viana Fialho Martins +6 more
doaj +1 more source
Feline infection by Leishmania infantum (syn. L. chagasi) has been described in areas where canine leishmaniosis is endemic. A wide variety of clinicopathological abnormalities have been reported in cats presenting clinical signs of leishmaniosis but ...
Manolis K. Chatzis +7 more
doaj +1 more source

