Results 71 to 80 of about 885 (162)

Diagnostic Challenges in Visceral Leishmaniasis in a 17‐Month‐Old Female: A Case Report

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Visceral leishmaniasis is an uncommon infectious disease. In this report, we present a case of VL in a 17‐month‐old child who presented with a fever and splenomegaly. After the patient failed to respond to several courses of antibiotics, a bone marrow aspirate confirmed the definitive diagnosis of VL, which was successfully treated with ...
Ahmed Sheikh Sobeh, Manal Soufan, Tasneem Sarakbi, Alaa Jaddouh, Feras Alharroush   +4 more
wiley   +1 more source

Transmission, reservoir hosts and control of zoonotic visceral leishmaniasis [PDF]

, 2009
Zoonotic visceral leishmaniasis (ZVL) caused by Leishmania infantum is an important disease of humans and dogs. Here we review aspects of the transmission and control of ZVL.
Courtenay, Orin, Quinnell, Rupert J., Quinnell, RJ, Courtenay, O   +3 more
core   +1 more source

Estudo fitoquímico e atividades leishmanicida, anticolinestarásica e antioxidante de extratos de Annona glabra L. (araticum panã)

Revista de Ciências Farmacêuticas Básica e Aplicada, 2015
O objetivo deste estudo foi investigar as principais classes de compostos químicos presentes em Annona grabra L. (Araticum panã), e avaliar o seu potencial biológico analisando suas atividades antioxidante, antiacetilcolinesterase e leishmanicida.
Antonio Adailson de Sousa Silva, Joana Barros Alexandre, Larissa Guerra Vieira, Suliane Praciano Rodrigues, Maria José Cajazeiras Falcão, Selene Maia Morais   +5 more
doaj   +2 more sources

Antileishmanial Activities of Carvacrol Nanoencapsulate in Biopolymeric Nanoparticles

Chemistry &Biodiversity, Volume 22, Issue 9, September 2025.
The study obtained biopolymeric nanoparticles containing carvacrol (NPCar) and evaluated their anti‐leishmanial activity. NPCar obtained presented physicochemical characteristics due to its ideal nanometric size and zeta potential, and low polydispersity index.
Joyce Cordeiro Borges, Anne Beatriz Cunha Barros, Leonardo Lima Cardoso, Tatjana de Lima Souza Keesen, Luís André de Almeida Campos, Isabella Macário Ferro Cavalcanti, Elisângela Afonso de Moura Kretzschmar   +6 more
wiley   +1 more source

Leishmania major: genetic heterogeneity of Iranian isolates by single-strand conformation polymorphism and sequence analysis of ribosomal DNA internal transcribed spacer.

, 2006
Protozoan parasites of Leishmania major are the causative agents of cutaneous leishmaniasis in different parts of Iran. We applied PCR-based methods to analyze L.
Mauricio, Isabel L, Al-Jawabreh, Amer, Alimohammadian, Mohammad Hossein, Tashakori, Mahnaz, Kuhls, Katrin, Farajnia, Safar, Schönian, Gabriele   +6 more
core   +1 more source

Therapeutic Effect of Barberry (Berberis vulgaris) Root Extract on Experimental Cutaneous Leishmaniosis in a BALB/c Mouse Model

Veterinary Medicine and Science, Volume 11, Issue 5, September 2025.
Barberry (Berberis vulgaris) root extract shows potential in treating cutaneous leishmaniasis caused by Leishmania major. In a BALB/c mouse model, treatment significantly reduced wound size and parasite load while enhancing inflammatory markers IL‐1 and IL‐6. These results highlight barberry's therapeutic promise against leishmaniasis.
Sadegh Shirian, Morteza Norouzi Cholcheh, Saeed Habibian Dehkordi, Behnam Bakhtiari Moghadam   +3 more
wiley   +1 more source

Cross-protective effect of a combined L5 plus L3 Leishmania major ribosomal protein based vaccine combined with a Th1 adjuvant in murine cutaneous and visceral leishmaniasis

Parasites & Vectors, 2014
Background Two Leishmania major ribosomal proteins L3 (LmL3) and L5 (LmL5) have been described as protective molecules against cutaneous leishmaniasis due to infection with L.
Laura Ramirez, Laura Corvo, Mariana C Duarte, Miguel A Chávez-Fumagalli, Diogo G Valadares, Diego M Santos, Camila I de Oliveira, Marta R Escutia, Carlos Alonso, Pedro Bonay, Carlos AP Tavares, Eduardo AF Coelho, Manuel Soto   +12 more
doaj   +1 more source

Infecção natural de Lutzomyia (Lutzomyia) longipalpis (Diptera: Psychodidae) por Leishmania infantum chagasi em flebotomíneos capturados no município de Janaúba, Estado de Minas Gerais, Brasil

Revista da Sociedade Brasileira de Medicina Tropical, 2011
INTRODUÇÃO: A leishmaniose visceral tem sido notificada em quase todos os estados do Brasil, e principalmente no norte de Minas Gerais, onde a doença é endêmica. Este estudo visou detectar a infecção natural de Lutzomyia longipalpis e identificar através
Érika Monteiro Michalsky, Karla de Sena Guedes, Fabiana de Oliveira Lara e Silva, João Carlos França-Silva, Consuelo Latorre Fortes Dias, Ricardo Andrade Barata, Edelberto Santos Dias   +6 more
doaj   +1 more source

IL‐12 and IFN‐γ in Response to Leishmania Infantum Antigens in Felines From an Endemic Area for Visceral Leishmaniasis

Parasite Immunology, Volume 47, Issue 8, August 2025.
ABSTRACT Visceral leishmaniasis is a potentially fatal zoonosis with an increasing incidence. Most infected felines present the disease in its subclinical form and demonstrate greater resistance to parasitemia than dogs. However, the role of cellular immunity in felines is still poorly understood. This study measured serum levels of interleukin (IL)‐12
João Victor Lé Lode, Lucas Takeshi Siqueira Ito, Gisele Mitsue Umino, Valéria Marçal Felix de Lima   +3 more
wiley   +1 more source

Role of CD200 immunomodulatory protein in macrophage infections by Leishmania (Leishmania) infantum chagasi.

, 2023
Parasitos do gênero Leishmania desenvolveram estratégias para garantir sua sobrevivência, manipulando mecanismos microbicidas de células de defesa, como macrófagos, e modulando a resposta imunológica do hospedeiro.
Portugal, Cinthia Siess
core   +1 more source