Results 21 to 30 of about 6,846 (239)

Antiproliferative and ultrastructural effects of phenethylamine derivatives on promastigotes and amastigotes of Leishmania ( Leishmania ) infantum chagasi

Parasitology International, 2016
Leishmania (Leishmania) infantum chagasi is one of the agents that cause visceral leishmaniasis. This disease occurs more frequently in third world countries, such as Brazil. The treatment is arduous, and is dependent on just a few drugs like the antimonial derivatives and amphotericin B.
Paula Ferreira Brasil, Júlia Araújo de Freitas, Anna Léa Silva Barreto, Camila M. Adade, Leandro Figueira Reis de Sá, Pamella Constantino-Teles, Fabiano T. Toledo, Bruno A. Sousa, A. C. Gonçalves, Maria Teresa Villela Romanos, J. V. Comasseto, Alcindo A. Dos Santos, Ana Claudia Tessis, Thaïs Souto-Padrón, Rosangela M.A. Soares, Antônio Ferreira‐Pereira   +15 more
openalex   +3 more sources

Complete conservation of an immunogenic gene (lcr1) in Leishmania infantum and Leishmania chagasi isolated from Iran, Spain and Brazi [PDF]

Journal of Vector Borne Diseases, 2010
Background & objectives: Kala-azar is the visceral and most severe form of leishmaniasis thatleads to death if untreated. The causative agents of visceral leishmaniasis (VL) are members ofLeishmania (L.) donovani complex which includes L.
H. Mahmoudzadeh-Niknam , F. Abrishami , M. Doroudian , M. Moradi , M.H. Alimohammadian , P. Parvizi
doaj   +1 more source

Brain Involvement in Leishmaniasis. [PDF]

Cell Biochem Funct
ABSTRACT Leishmaniasis is a neglected tropical disease caused by infection with the protozoan parasite Leishmania and it is a significant global health problem. The disease has a wide clinical spectrum, from tegumentary leishmaniasis (TL) that encompasses cutaneous (CL), mucosal (ML) and cutaneous‐diffuse (CDL) forms, to the potentially fatal systemic ...
Freitas CS, Coelho EAF, Christodoulides M.   +2 more
europepmc   +2 more sources

Assessment of Leishmania exposure in blood donors from a non-endemic urban area: A study in São Paulo. [PDF]

Vox Sang
Abstract Background and Objectives According to the World Health Organization, more than 1 billion people are at risk of leishmaniasis in over 89 countries. Environmental changes such as deforestation, urban expansion and climate change facilitate the spread of sand fly vectors and reservoirs, increasing disease transmission.
de Lima IS, Ferreira SC, Nishiya AS, Kesper N, Ferreira JE, de Castro Gomes CM, Derriga J, Dantas KC, Polato SPG, Salles NA, Lindoso JAL, Fanciani T, de Almeida-Neto C, Rocha V, Mendrone A.   +14 more
europepmc   +2 more sources

Reproduction of Leishmania (Leishmania ) infantum chagasi in conditioned cell culture growth medium [PDF]

Revista do Instituto de Medicina Tropical de São Paulo, 2006
Leishmanias can be produced by inoculation in conditioned McCoy cell culture growth medium (CGM). Leishmania (Leishmania) infantum chagasi (100 parasites) grown in NNN medium was inoculated in 2.5 mL CGM, kept in plates (24 wells) and its multiplication was observed for five days (120 hours).
Nogueira, Yeda L., Galati, Eunice A.B.
openaire   +6 more sources

Heterogeneities in leishmania infantum infection : using skin parasite burdens to identify highly infectious dogs [PDF]

, 2013
Background: The relationships between heterogeneities in host infection and infectiousness (transmission to arthropod vectors) can provide important insights for disease management.
A Mohammadiha, A Mohammadiha, ANS Maia-Elkhoury, AP da Costa-Val, AP Galvani, BL Travi, BLA Vercosa, C Carson, C Fraser, C Mary, C Mary, CDL Oliveira, CHN Costa, CHN Costa, Connor Carson, DJ Shaw, DW Dowdy, EM Michalsky, GA Soper, IFGd Amorim, JO Lloyd-Smith, KJ Esch, KTD Eames, L Dipineto, L Manna, L Manna, L Matthews, Leo Calvo-Bado, LHdS Marques, LLH Lau, Lourdes M. Garcez, LVR Lima, M Chase-Topping, Marleen Boelaert, MEJ Woolhouse, O Courtenay, O Courtenay, O Courtenay, O Francino, Orin Courtenay, PF Quaresma, R Lainson, R Molina, R Molina, R Verin, RA Stein, RB Gomes, RC Giunchetti, RJ Quinnell, RJ Quinnell, RJ Quinnell, RJ Quinnell, RM Anderson, RM May, Rupert J. Quinnell, S Bossolasco, SdA Ferreira   +56 more
core   +13 more sources

Cortisol Regulates PD-1 and IL-12 in Canine Leishmaniasis. [PDF]

Parasite Immunol
ABSTRACT Canine visceral leishmaniasis (CanL) is a tropical zoonosis caused by Brazil's protozoan Leishmania (L.) infantum. Disorders in the hypothalamic–pituitary–adrenal (HPA) axis have been reported in human and experimental visceral leishmaniasis, but not yet in canine leishmaniasis.
Ito LTS, Umino GM, Guimarães MA, de Souza BMM, Soares SF, Pereira LEAL, de Lima VMF.   +6 more
europepmc   +2 more sources

Imidazolium salts as an alternative for anti-Leishmania drugs: Oxidative and immunomodulatory activities

Frontiers in Immunology, 2023
In this study we explored the previously established leishmanicidal activity of a complementary set of 24 imidazolium salts (IS), 1-hexadecylimidazole (C16Im) and 1-hexadecylpyridinium chloride (C16PyrCl) against Leishmania (Leishmania) amazonensis and ...
Fernanda Giesel Baldissera, Fernanda Giesel Baldissera, Tiago Fazolo, Tiago Fazolo, Matheus Brasil da Silva, Paulo Cesar de Santana Filho, Vinícius Demétrio da Silva, David Max Rivillo Perez, Joice Sandra Klitzke, Eduardo Giovanni de Oliveira Soares, Luiz Carlos Rodrigues Júnior, Luiz Carlos Rodrigues Júnior, Alessandra Peres, Alessandra Peres, Eliane Dallegrave, Kely Campos Navegantes-Lima, Marta Chagas Monteiro, Henri Stephan Schrekker, Pedro Roosevelt Torres Romão, Pedro Roosevelt Torres Romão, Pedro Roosevelt Torres Romão   +20 more
doaj   +1 more source

Cutaneous Leishmaniasis Mimicking a Nasal Tumor: A Case Report. [PDF]

Case Rep Infect Dis
Leishmaniasis is a disease caused by Leishmania protozoa that is transmitted to the patient by sand flies. Depending on the Leishmania species, the disease can present with cutaneous, mucosal, or multiorgan involvement. Cutaneous leishmaniasis can present with diverse clinical manifestations mimicking other diseases.
Hekmat M, Namazi MR, Najibi AH, Shirazi Yeganeh B, Fazelzadeh Haghighi N.   +4 more
europepmc   +2 more sources

Subclinical Muscle Injuries in Dogs Infected with Leishmania (Leishmania) infantum chagasi [PDF]

Brazilian Journal of Veterinary Pathology, 2012
Although canine visceral leishmaniasis (CVL) has been extensively studied, muscular damage due to Leishmania (Leishmania) infantum chagasi infection remains to be fully established. The aim of this study was to describe the electromyographic and histological changes, as well as search for the presence of amastigote forms of Leishmania spp, CD3+ T ...
Gomes, Ana Amélia Domingues, Laurenti, Márcia Dalastra, Ferraro, Gisela Cristiane, de Camargo, Mauro Henrique Bueno, Costa, Denis Carvalho, Machado, Gisele Fabrino, Perri, Silvia Helena Venturoli, Marcondes, Mary   +7 more
openaire   +1 more source