Revista do Instituto de Medicina Tropical de São Paulo, 2015 SUMMARY American tegumentary leishmaniasis (ATL) is an infectious disease caused by protozoa of the genus Leishmania, and transmitted by sandflies. In the state of Rio de Janeiro, almost all of the cases of American tegumentary leishmaniasis (ATL) are ...
Marcelo Rosandiski LYRA +6 more
doaj +1 more source
LXR deficiency confers increased protection against visceral Leishmania infection in mice. [PDF]
PLoS Neglected Tropical Diseases, 2010 The liver X receptors (LXRs) are a family of nuclear receptor transcription factors that are activated by oxysterols and have defined roles in both lipid metabolism and cholesterol regulation.
Kevin W Bruhn +10 more
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Attenuation of Leishmania infantum chagasi Metacyclic Promastigotes by Sterol Depletion [PDF]
Infection and Immunity, 2013 ABSTRACTThe infectious metacyclic promastigotes ofLeishmaniaprotozoa establish infection in a mammalian host after they are deposited into the dermis by a sand fly vector. SeveralLeishmaniavirulence factors promote infection, including the glycosylphosphatidylinositol membrane-anchored major surface protease (MSP).
Chaoqun, Yao +6 more
openaire +2 more sources
Evolutionary history of Leishmania killicki (synonymous Leishmania tropica) and taxonomic implications [PDF]
, 2015 Background: Leishmania (L.) killicki is responsible for the chronic cutaneous leishmaniasis. The taxonomic status of this parasite is still not well defined. It was suggested on one hand to include this taxon within L.
Babba, Hamouda +11 more
core +3 more sources
Leishmania infantum ecto-nucleoside triphosphate diphosphohydrolase-2 is an apyrase involved in macrophage infection and expressed in infected dogs. [PDF]
PLoS Neglected Tropical Diseases, 2014 Visceral leishmaniasis is an important tropical disease, and Leishmania infantum chagasi (synonym of Leishmania infantum) is the main pathogenic agent of visceral leishmaniasis in the New World. Recently, ecto-nucleoside triphosphate diphosphohydrolases (
Raphael De Souza Vasconcellos +19 more
doaj +1 more source
Semina: Ciências Agrárias, 2011 Among mammals, the canids are most often infected by Leishmania sp. This paper reports the occurrence of Leishmania (Leishmania) infantum chagasi as well as the presence of intranuclear inclusions resembling viral particles of canine adenovirus-1 in a ...
Luciano Nakazato +5 more
doaj +1 more source
Heterogeneity of Leishmania infantum chagasi Kinetoplast DNA in Teresina (Brazil) [PDF]
The American Society of Tropical Medicine and Hygiene, 2010 Leishmania infantum chagasi is the causative agent of visceral leishmaniasis in Brazil. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis of kinetoplast DNA (kDNA) minicircles was used to evaluate genetic profiles of 48 Leishmania infantum chagasi strains from dog and human parasite cultures, fresh collected dog ...
Diego Peres, Alonso +4 more
openaire +2 more sources
Parasites & Vectors, 2012 Background Sandflies are vectors of Leishmania, the causative agent of leishmaniasis in mammalian hosts, including humans. The protozoan parasite is transmitted by the sandfly bite during salivation that occurs at the moment of blood feeding.
Secundino Nagila FC +5 more
doaj +1 more source
Use of a recombinant cysteine proteinase from Leishmania (Leishmania) infantum chagasi for the Immunotherapy of canine visceral Leishmaniasis. [PDF]
PLoS Negl Trop Dis, 2014 Ferreira JH +4 more
europepmc +2 more sources
Killed but metabolically active Leishmania infantum as a novel whole-cell vaccine for visceral leishmaniasis [PDF]
, 2012 There are currently no effective vaccines for visceral leishmaniasis, the second most deadly parasitic infection in the world. Here, we describe a novel whole-cell vaccine approach using Leishmania infantum chagasi promastigotes treated with the psoralen
Beverley, Stephen M +11 more
core +2 more sources