Autochthonous case of Canine Visceral Leishmaniasis in a non-endemic area in Minas Gerais, Brazil
Pesquisa Veterinária Brasileira: Visceral Leishmaniasis by Leishmania infantum chagasi is an endemic zoonosis present in many areas of Brazil. This parasite needs reservoirs for maintenance of the infection and the presence of dogs in urban areas is a key factor for the spread of ...
Mariana Teixeira de Faria +7 more
doaj +1 more source
Revista Brasileira de Parasitologia Veterinária, 2011 Leishmaniasis is a zoonotic disease that affects 12 million people worldwide. Several mammalian species can serve as a reservoir for this disease. Dogs are the main reservoir for visceral leishmaniasis in urban areas, which has become a serious public ...
Márcia Mariza Gomes Jusi +5 more
doaj +1 more source
A prime/boost DNA/Modified vaccinia virus Ankara vaccine expressing recombinant Leishmania DNA encoding TRYP is safe and immunogenic in outbred dogs, the reservoir of zoonotic visceral leishmaniasis [PDF]
Previous studies demonstrated safety, immunogenicity and efficacy of DNA/modified vaccinia virus Ankara (MVA) prime/boost vaccines expressing tryparedoxin peroxidase (TRYP) and Leishmania homologue of the mammalian receptor for activated C kinase (LACK ...
Alcami, Antonio +7 more
core +1 more source
Diagnostic antigens for visceral leishmaniasis: clarification of nomenclatures. [PDF]
, 2017 BACKGROUND: Stimulated by the increasing recent use of 'K' or 'rK' nomenclature for antigens reported for visceral leishmaniasis (VL) diagnostic serology, we wished to give a chronological synopsis of their reporting and the potentially confusing ...
Bhattacharyya, Tapan +2 more
core +1 more source
Immunobiology of visceral leishmaniasis
Frontiers in Immunology, 2012 Visceral leishmaniasis (VL), commonly known as kala-azar, is caused by Leishmania donovani and Leishmania infantum (Leishmania chagasi in the Americas). These Leishmania species infect macrophages throughout the viscera, and parasites are typically found
Susanne eNylén, Rajiv eKumar
doaj +1 more source
Macrophage and T-cell gene expression in a model of early infection with the protozoan Leishmania chagasi. [PDF]
PLoS Neglected Tropical Diseases, 2008 Visceral leishmaniasis is a potentially fatal infectious disease caused by the protozoan parasite Leishmania infantum/chagasi in the New World, or by L. donovani or L. infantum/chagasi in the Old World.
Nicholas A Ettinger, Mary E Wilson
doaj +1 more source
Immunological selection for Leishmania (Viannia) braziliensis antigens.
, 2002 Comparative ELISA and selective immunoblotting procedures were used in attempts to identify differential serological indicators of infection with the Leishmania (Viannia) braziliensis complex, infection with the L.
Cuba Cuba, CA +3 more
core +1 more source
One-year timeline kinetics of cytokine-mediated cellular immunity in dogs vaccinated against visceral leishmaniasis [PDF]
, 2015 BACKGROUND: The main control strategy for visceral leishmaniasis in Brazil has been based on the elimination of seropositive dogs, although this is not widely accepted. In this context, the use of a long-lasting protective vaccine against canine visceral
Bruno H Marteleto +10 more
core +2 more sources
Tropical Medicine &International Health, EarlyView.ABSTRACT Visceral leishmaniasis (VL) is a human neglected tropical disease in which dogs participate as reservoirs of the etiological agent Leishmania chagasi. The identification of infected dogs is important to the control of VL, and recombinant proteins are strong antigen candidates for canine visceral leishmaniasis (CVL) serodiagnosis. In this work,
Thaís Viana Fialho Martins +12 more
wiley +1 more source
Study of Leishmania pathogenesis in mice : experimental considerations [PDF]
, 2015 Although leishmaniases are endemic in 98 countries, they are still considered neglected tropical diseases. Leishmaniases are characterized by the emergence of new virulent and asymptomatic strains of Leishmania spp.
A Asadpour +65 more
core +4 more sources