Results 181 to 190 of about 72,203 (213)

Amplification of the H locus in Leishmania infantum

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1994
We have selected for a Leishmania infantum cell line resistant to high levels of methotrexate (MTX). The resulting cells were 1233-fold more resistant than wild-type and contained amplified H-region circles. Homologous genes to the antifolate resistant ltdh gene and to the P-glycoprotein ltpgpA gene of Leishmania tarentolae were observed to be ...
M J, Chiquero, A, Olmo, P, Navarro, L M, Ruiz-Perez, S, Castanys, D, Gonzalez-Pacanowska, F, Gamarro   +6 more
openaire   +2 more sources

Molecular tracking of infections by Leishmania infantum

Transactions of the Royal Society of Tropical Medicine and Hygiene, 2001
Leishmania infantum is a major opportunistic parasite in patients with acquired immune deficiency syndrome and is very variable in these subjects. Isoenzyme characterization is not able to explain this variability, since half of the stocks isolated from patients co-infected with human immunodeficiency virus and Leishmania belong to zymodeme MON-1 ...
M A, Morales, C, Chicharro, M, Ares, C, Cañavate, D C, Barker, J, Alvar   +5 more
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Susceptibility of Cebus nigrivittatus to Leishmania infantum

The Journal of Parasitology, 1986
is associated with nausea, vomiting, and deafness with tinnitus. Such afflicted individuals cannot walk and have to lie down in bed without turning over. Our observations on the motility of dolphins that were pushed back into the water or captured in a pool indicated a disturbance of equilibrium. Odontoceti suffering from acute octavus neuropathy might
I, Vouldoukis, W, Ogunkolade, L, Strazielle, I, Ploton, L, Monjour   +4 more
openaire   +2 more sources

Coexistence of Leishmania tropica and Leishmania infantum in Sefrou province, Morocco

Acta Tropica, 2014
Cutaneous leishmaniasis (CL) has been recently emerged in new foci, posing a public health problem. Increasing cases of CL have been reported during recent years in Sefrou province, a previously non-endemic area. The present study was designed for epidemiological and parasitological characterization of the disease for the first time in this area.
Hmamouch Asmae, Amarir Fatima, Fellah Hajiba, Karzaz Mbarek, Bekhti Khadija, Rhajaoui Mohamed, Sebti Faiza   +6 more
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Mucocutaneous Leishmaniasis due to Leishmania (Leishmania) infantum: Biochemical Characterization

The American Journal of Tropical Medicine and Hygiene, 1990
A vegetative mass in the right nasal cavity of a 62-year-old man from Palma de Mallorca, Spain, was found to be due to Leishmania. The organism was isolated in culture and characterized by in situ hybridization, Southern blot hybridization, and isoenzyme analysis; it was thus demonstrated to be the most common enzyme variant 1 (MON 1) of Leishmania ...
J, Alvar, J A, Ballesteros, R, Soler, A, Benito, G J, van Eys, G J, Schoone, B, Cabrer   +6 more
openaire   +2 more sources

First evidence of autochthonous cases of Leishmania (Leishmania) infantum in horse (Equus caballus) in the Americas and mixed infection of Leishmania infantum and Leishmania (Viannia) braziliensis

Veterinary Parasitology, 2013
This study reports the first evidence of infection by Leishmania infantum in Equus caballus in Americas and the first mixed infection of L. infantum/Leishmania braziliensis on this mammalian species in the world. The diagnoses was based on presence of parasites in lesions and bone marrow aspirates, their identification by using specific primers for L ...
Isabel R, Soares, Soraia O, Silva, Filipe Moraghi, Moreira, Luan Gavião, Prado, Priscila, Fantini, Renata de Pino Albuquerque, Maranhão, José Monteiro, da Silva Filho, Maria Norma, Melo, Maristela S, Palhares   +8 more
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Feline leishmaniosis due to Leishmania infantum in Italy

Veterinary Parasitology, 2002
A case of leishmaniosis in domestic cats (Felis catus domesticus) is described. The subject showed a nodular lesion on the eyelid. The diagnosis was achieved by serological, parasitological, and light and electron microscopic investigations. By molecular techniques the aetiological agent was identified as belonging to Leishmania infantum, the species ...
POLI, ALESSANDRO, ABRAMO, FRANCESCA, Barsotti P, Leva S, Gramiccia M, Ludovisi A, MANCIANTI, FRANCESCA   +6 more
openaire   +3 more sources

Specificity and kinetics of a mitochondrial peroxiredoxin of Leishmania infantum

Free Radical Biology and Medicine, 2002
In Kinetoplastida, comprising the medically important parasites Trypanosoma brucei, T. cruzi, and Leishmania species, 2-Cys peroxiredoxins described to date have been shown to catalyze reduction of peroxides by the specific thiol trypanothione using tryparedoxin, a thioredoxin-related protein, as an immediate electron donor.
Helena, Castro, Heike, Budde, Leopold, Flohé, Birgit, Hofmann, Heinrich, Lünsdorf, Joseph, Wissing, Ana M, Tomás   +6 more
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Canine Transmissible Venereal Tumour Parasitized by Leishmania infantum

Veterinary Research Communications, 2003
Hersonissos, Crete ...
CATONE, Giuseppe, MARINO, Gabriele, POGLAYEN, Giovanni, GRAMICCIA M, LUDOVISI A, ZANGHI', Antonina   +5 more
openaire   +6 more sources

Immunization of dogs with a Leishmania infantum-derived vaccine

Veterinary Parasitology, 1988
A partially-purified extract of Leishmania infantum has been administered to healthy dogs. Post-immunization sera were found to neutralize the infectivity of L. infantum and to abate the development of L. major. Muramyl dipeptide and one of its derivates, murabutide, were the best adjuvants.
B W, Ogunkolade, I, Vouldoukis, D, Frommel, B, Davoust, A, Rhodes-Feuillette, L, Monjour   +5 more
openaire   +2 more sources