Results 31 to 40 of about 81,351 (300)

Genes and Chromosomes of Leishmania infantum [PDF]

open access: yesMemórias do Instituto Oswaldo Cruz, 1997
During recent years, several Leishmania infantum genes have been cloned and characterized. Here, we have summarized the available information on the gene organization and expression in this protozoan parasite. From a comparative analysis, the following outstanding features were found to be common to most of the genes characterized: tandemly organized ...
María Requena, Jose   +3 more
openaire   +5 more sources

A Case of Leishmania Infantum Mimicking Lymphoma

open access: yesIndian Journal of Dermatology, 2023
Leishmaniasis is a parasitic infection caused by an obligate intracellular protozoon transmitted by infected sand flies. Cutaneous leishmaniasis (CL) is a skin disease known in our country as oriental sore, which heals, leaving a scar in place, mainly on the skin and sometimes in the mucous membrane.
Gulnaz Culha   +3 more
openaire   +3 more sources

Study of ocular manifestations and humoral immune response in eyes of dogs with leishmaniasis

open access: yesVeterinary Medicine and Science, 2023
Background Ocular manifestations in dogs with leishmaniasis are frequent and complications in affected tissues can lead to blindness. Immune processes play a very important role in the pathogenesis of ocular inflammation.
Amel F. El Goulli   +6 more
doaj   +1 more source

Colonization and genetic diversification processes of Leishmania infantum in the Americas

open access: yesCommunications Biology, 2021
Leishmania infantum causes visceral leishmaniasis, a deadly vector-borne disease introduced to the Americas during the colonial era. This non-native trypanosomatid parasite has since established widespread transmission cycles using alternative vectors ...
P. Schwabl   +17 more
semanticscholar   +1 more source

Leishmania infantum in US-Born Dog [PDF]

open access: yesEmerging Infectious Diseases, 2020
Leishmaniasis is a vectorborne disease that can infect humans, dogs, and other mammals. We identified one of its causative agents, Leishmania infantum, in a dog born in California, USA, demonstrating potential for autochthonous infections in this country. Our finding bolsters the need for improved leishmaniasis screening practices in the United States.
Dennis R Spann   +2 more
openaire   +4 more sources

Structures of the Leishmania infantum polymerase beta [PDF]

open access: yesDNA Repair, 2014
Protozoans of the genus Leishmania, the pathogenic agent causing leishmaniasis, encode the family X DNA polymerase Li Pol β. Here, we report the first crystal structures of Li Pol β. Our pre- and post-catalytic structures show that the polymerase adopts the common family X DNA polymerase fold. However, in contrast to other family X DNA polymerases, the
Ana Alonso   +6 more
openaire   +4 more sources

Genetic Diversity and Population Structure of Leishmania infantum in Morocco as Revealed by Multilocus Sequence Typing (MLST) Approach

open access: yesPathogens, 2023
Leishmania infantum is endemic in Morocco, and it causes both visceral (VL) and cutaneous leishmaniasis (CL). In this study, the multilocus sequence typing (MLST) approach was used to investigate the phylogeny and population structure of Leishmania ...
Sara El Mazini   +10 more
doaj   +1 more source

New diarylsulfonamide inhibitors of Leishmania infantum amastigotes

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2021
New drugs against visceral leishmaniasis with mechanisms of action differing from existing treatments and with adequate cost, stability, and properties are urgently needed. No antitubulin drug is currently in the clinic against Leishmania infantum, the causative agent of visceral leishmaniasis in the Mediterranean area. We have designed and synthesized
Myriam González   +5 more
openaire   +6 more sources

First molecular detection of Leishmania (Leishmania) infantum chagasi in a domestic cat (Felis catus) from an urban area in eastern Amazon [PDF]

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2023
Background: Domestic cats have been implicated as accidental hosts of Leishmania sp. However, in recent years, the recurrent description of new cases in endemic and nonendemic areas draw attention to the potential epidemiological role of cats as ...
Délia Cristina Figueira Aguiar   +7 more
doaj   +1 more source

Leishmania infantum and Dirofilaria immitis infections in Italy, 2009–2019: changing distribution patterns

open access: yesParasites & Vectors, 2020
For long time, canine leishmaniosis (CanL) was considered endemic in the southern, central, and insular regions of Italy, whereas heartworm disease (HW) caused by Dirofilaria immitis was considered endemic in the northern region and in the swampy Po ...
J. Mendoza-Roldan   +7 more
semanticscholar   +1 more source

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