Results 51 to 60 of about 79,414 (305)

Antiparasitic effect of synthetic aromathecins on Leishmania infantum [PDF]

BMC Veterinary Research, 2019
Abstract Background Canine leishmaniasis is a zoonotic disease caused by Leishmania infantum, being the dogs one of the major reservoirs of human visceral leishmaniasis. DNA topology is a consolidated target for drug discovery. In this regard, topoisomerase IB – one of the enzymes controlling DNA topology – has been poisoned by hundreds of compounds ...
Rosa M. Reguera, Raquel Álvarez-Velilla, Bárbara Domínguez-Asenjo, Camino Gutiérrez-Corbo, Rafael Balaña-Fouce, Mark Cushman, Yolanda Pérez-Pertejo   +6 more
openaire   +5 more sources

Association between canine leishmaniosis and Ehrlichia canis co-infection: a prospective case-control study [PDF]

, 2018
Background In the Mediterranean basin, Leishmania infantum is a major cause of disease in dogs, which are frequently co-infected with other vector-borne pathogens (VBP).
A Mazeris, A Saha, A Sainz, AS De Tommasi, C Attipa, C Attipa, C Maia, CB Cardinot, CF Alves, Charalampos Attipa, Chris Helps, CL Barbieri, CLA Ehrlichiosis, D Chochlakis, D Otranto, D Otranto, David Morris, Francesca Soutter, G Baneth, G Baneth, J Alvar, J Franca-Costa, J Le Gal, J Moreno, K Katherine, Kostas Papasouliotis, L Cortese, L Cortese, L Solano-Gallego, L Solano-Gallego, Laia Solano-Gallego, M Novacco, M Olivier, M-D Tabar, MG Vrhovec, MJ Day, MJ Grigg, P Parola, P Seneviratna, R Killick-Kendrick, RB Kline, RJ Quinnell, RN Davidson, S Carver, S Davies, S Harrus, S Harrus, S Tasker, Scott Carver, SE Shaw, Séverine Tasker, T Bouzouraa, V Pintado, WH Pryor Jr, Y Mekuzas, Y Rosseel   +55 more
core   +5 more sources

Leishmania (infantum) chagasi in canine urinary sediment [PDF]

Revista Brasileira de Parasitologia Veterinária, 2015
Canine visceral leishmaniasis (CVL) is difficult to diagnosis, mainly due to the presence of asymptomatic animals, the diversity of clinical symptoms and the difficulty in obtaining diagnostic evidence of high sensitivity and specificity. The purpose of this study was to diagnose CVL in urinary sediment of 70 dogs of different breeds, sexes and ages ...
Mendonça, Ivete Lopes de, Batista, Joilson Ferreira, Alves, Leucio Camara   +2 more
openaire   +5 more sources

Role of the lipoxin A4 receptor in the development of neutrophil extracellular traps in Leishmania infantum infection

Parasites & Vectors, 2019
Background Neutrophils play an immunomodulatory role through the release of neutrophil extracellular traps (NETs). NETs are released in response to Leishmania infection, but the mechanism of NET extrusion has not been elucidated.
Furong Wei, Wenci Gong, Junyun Wang, Yuetao Yang, Jianxiu Liu, Yanjuan Wang, Jianping Cao   +6 more
doaj   +1 more source

Proteome Profiling of Leishmania Infantum Promastigotes

Journal of Eukaryotic Microbiology, 2011
ABSTRACT. A proteome analysis of the promastigote stage of the trypanosomatid parasite Leishmania infantum (MON‐1 zymodeme) is described here for the first time. Total protein extracts were prepared at early logarithmic and stationary phases of replicate axenic cultures and processed by 2D electrophoresis (pH 3–10).
Alcolea, Pedro J., Alonso, Ana, Larraga, Vicente   +2 more
openaire   +4 more sources

Detection of Leishmania infantum DNA mainly in Rhipicephalus sanguineus male ticks removed from dogs living in endemic areas of canine leishmaniosis

Parasites & Vectors, 2012
Background Sand flies are the only biologically adapted vectors of Leishmania parasites, however, a possible role in the transmission of Leishmania has been proposed for other hematophagous ectoparasites such as ticks.
Solano-Gallego Laia, Rossi Luca, Scroccaro Anna, Montarsi Fabrizio, Caldin Marco, Furlanello Tommaso, Trotta Michele   +6 more
doaj   +1 more source

A Calcium- and GTP-Dependent Transglutaminase in Leishmania infantum

Veterinary Sciences, 2023
While human and animal leishmaniasis affect several millions of people worldwide, L. infantum is the species responsible for visceral leishmaniasis in Europe, Middle East, and America. Antileishmanial drugs present issues associated with drug toxicity and increasing parasite resistance.
Almugadam, Shawgi Hago, Trentini, Alessandro, Maritati, Martina, Contini, Carlo, Manfrinato, Maria Cristina, Cervellati, Carlo, Bellini, Tiziana, Hanau, Stefania   +7 more
openaire   +4 more sources

Follow-up monitoring in a cat with leishmaniosis and coinfections with Hepatozoon felis and ‘Candidatus Mycoplasma haemominutum’ [PDF]

, 2017
Case summary A 6-year-old female neutered domestic shorthair cat from Cyprus was presented with multiple ulcerated skin nodules. Cytology and histopathology of the lesions revealed granulomatous dermatitis with intracytoplasmic organisms, consistent ...
Attipa, C, Baneth, G, Brooks-Brownlie, H, Martínez-Orellana, P, Nachum-Biala, Y, Neofytou, K, Solano-Gallego, L, Tasker, S, Yiapanis, C   +8 more
core   +5 more sources

Paf-Metabolic Enzymes and Paf-like Activity in and Promastigotes

European Journal of Inflammation, 2011
Leishmania spp are obligate intracellular protozoan parasites of the mononuclear phagocyte system that cause a spectrum of diseases known as leishmaniasis.
P. Chatzovoulos, A.B. Tsoupras, M. Samiotaki, G. Panayotou, C.A. Demopoulos, E. Dotsika   +5 more
doaj   +1 more source

Leishmania (Leishmania) infantum chagasi em canídeos silvestres mantidos em cativeiro, no Estado de Mato Grosso Leishmania (Leishmania) infantum chagasi in wild canids kept in captivity in the State of Mato Grosso

Revista da Sociedade Brasileira de Medicina Tropical, 2010
INTRODUÇÃO: Leishmaniose visceral é uma zoonose que acomete diversos mamíferos tendo os canídeos domésticos como principais reservatórios em ambiente urbano.
Nely Pinheiro Souza, Arleana do Bom Parto Ferreira de Almeida, Tatiana Pádua Tavares de Freitas, Regina Celia Rodrigues da Paz, Valéria Dutra, Luciano Nakazato, Valéria Régia Franco Sousa   +6 more
doaj   +1 more source