Results 61 to 70 of about 72,203 (213)

Ethanolic extract of Croton blanchetianus Ball induces mitochondrial defects in Leishmania amazonensis promastigotes [PDF]

Anais da Academia Brasileira de Ciências, 2020
Leishmaniasis is a neglected disease caused by Leishmania. Chemotherapy remains the mainstay for leishmaniasis control; however, available drugs fail to provide a parasitological cure, and are associated with high toxicity. Natural products are promising
KATILY L.G. PEREIRA, NANCY B.R. VASCONCELOS, JULIANA V.C. BRAZ, JOB D.F. INÁCIO, CHARLES S. ESTEVAM, CRISTIANE B. CORREA, ROBERTA P.M. FERNANDES, ELMO E. ALMEIDA-AMARAL, RICARDO SCHER   +8 more
doaj   +1 more source

The molecular epidemiology and phylogeography of Trypanosoma cruzi and parallel research on Leishmania: looking back and to the future. [PDF]

, 2009
Trypanosoma cruzi is the protozoan agent of Chagas disease, and the most important parasitic disease in Latin America. Protozoa of the genus Leishmania are global agents of visceral and cutaneous leishmaniasis, fatal and disfiguring diseases.
Fitpatrick, S., Miles, M.A., Fitzpatrick, S, Mauricio, IL, Yeo, M., Gaunt, MW, Mauricio, I.L., Llewellyn, MS, Lewis, MD, Miles, MA, Baleela, R, Lewis, M.D., Gaunt, M.W., Yeo, M, Baleela, R., Llewellyn, M.S.   +15 more
core   +1 more source

Seroprevalence and spatial distribution of canine leishmaniasis in an endemic region in Brazil: how has the situation changed after 10 years?

Revista da Sociedade Brasileira de Medicina Tropical
INTRODUCTION: Herein, we assessed the seroprevalence and spatial distribution of Leishmania infantum in dogs in Garanhuns, Northeastern Brazil. METHODS: Sera samples (n = 242) were analyzed using an enzyme-linked immunosorbent assay (ELISA).
Talita Nayara Bezerra Lins, Islanne Barbosa de Souza, Guilherme Mota Maciel do Rêgo Barros, Cléber Vinícius Brito dos Santos, Rômulo Pessoa e Silva, Leucio Câmara Alves, Gílcia Aparecida de Carvalho, Rafael Antonio Nascimento Ramos   +7 more
doaj   +1 more source

Systemic treatment of cutaneous leishmaniasis: A systematic review and meta‐analysis

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This systematic review and meta‐analysis assessed systemic treatments for cutaneous leishmaniasis across 83 studies and 4603 patients. Treatment efficacies of meglumine antimoniate, miltefosine, azoles, pentamidine, and liposomal amphotericin B varied by region and species. Miltefosine showed consistent evidence across multiple settings.
Maximilian Egg, Dennis Wienand, Lucie Harpain, Marie‐Luise Brunner‐Kovarik, Julia Walochnik, Markus Wiesmueller, Amélie Hampel, Tibor Spath, Lukas Trnka, Judit Simon, Alessandra Handisurya   +10 more
wiley   +1 more source

Comparison of visceral leishmaniasis diagnostic antigens in African and Asian Leishmania donovani reveals extensive diversity and region-specific polymorphisms. [PDF]

, 2013
BACKGROUND: Visceral leishmaniasis (VL), caused by infection with Leishmania donovani complex, remains a major public health problem in endemic regions of South Asia, East Africa, and Brazil. If untreated, symptomatic VL is usually fatal.
Bhattacharyya, T., Miles, M. A., Miles, Michael A, Michael A Miles, Bhattacharyya, Tapan, Boelaert, M., Boelaert, Marleen, Tapan Bhattacharyya, Marleen Boelaert, Boelaert Marleen, Miles Michael A., Bhattacharyya Tapan   +11 more
core   +1 more source

Leishmania infantum [PDF]

Trends in Parasitology, 2020
Tiago D, Serafim, Eva, Iniguez, Fabiano, Oliveira   +2 more
openaire   +3 more sources

Proteome Profiling of Leishmania Infantum Promastigotes

Journal of Eukaryotic Microbiology, 2011
ABSTRACT. A proteome analysis of the promastigote stage of the trypanosomatid parasite Leishmania infantum (MON‐1 zymodeme) is described here for the first time. Total protein extracts were prepared at early logarithmic and stationary phases of replicate axenic cultures and processed by 2D electrophoresis (pH 3–10).
Alcolea, Pedro J., Alonso, Ana, Larraga, Vicente   +2 more
openaire   +3 more sources

Study of in vitro biological activity of thiazoles on Leishmania (Leishmania) infantum

Journal of Global Antimicrobial Resistance, 2020
In the prospection of possible agents against neglected diseases, thiazole compounds are presented as promising candidates and are known to have activity against trypanosomatid parasites. Thus, this work aimed to evaluate the effects of thiazole compounds on Leishmania infantum, the aetiological agent of visceral leishmaniasis.Thiazole compounds (five ...
Vinícius Vasconcelos Gomes de Oliveira, Mary Angela Aranda de Souza, Rafaela Ramos Mororó Cavalcanti, Marcos Veríssimo de Oliveira Cardoso, Ana Cristina Lima Leite, Valdemiro Amaro da Silva Junior, Regina Célia Bressan Queiroz de Figueiredo   +6 more
openaire   +3 more sources

Mucocutaneous Leishmaniasis due to Leishmania infantum Infection

Acta Dermato-Venereologica, 2022
Abstract is missing (Short communcation)
Kai-Philipp Linse, Christian Bogdan, Holger A. Haenssle, Ferdinand Toberer   +3 more
openaire   +3 more sources

Canine antibody response to Phlebotomus perniciosus bites negatively correlates with the risk of Leishmania infantum transmission. [PDF]

PLoS Neglected Tropical Diseases, 2011
BACKGROUND: Phlebotomine sand flies are blood-sucking insects that can transmit Leishmania parasites. Hosts bitten by sand flies develop an immune response against sand fly salivary antigens.
Michaela Vlkova, Iva Rohousova, Jan Drahota, Dorothee Stanneck, Eva Maria Kruedewagen, Norbert Mencke, Domenico Otranto, Petr Volf   +7 more
doaj   +1 more source