Results 81 to 90 of about 32,531 (219)

Association between canine leishmaniosis and Ehrlichia canis co-infection: a prospective case-control study [PDF]

, 2018
Background In the Mediterranean basin, Leishmania infantum is a major cause of disease in dogs, which are frequently co-infected with other vector-borne pathogens (VBP).
A Mazeris, A Saha, A Sainz, AS De Tommasi, C Attipa, C Attipa, C Maia, CB Cardinot, CF Alves, Charalampos Attipa, Chris Helps, CL Barbieri, CLA Ehrlichiosis, D Chochlakis, D Otranto, D Otranto, David Morris, Francesca Soutter, G Baneth, G Baneth, J Alvar, J Franca-Costa, J Le Gal, J Moreno, K Katherine, Kostas Papasouliotis, L Cortese, L Cortese, L Solano-Gallego, L Solano-Gallego, Laia Solano-Gallego, M Novacco, M Olivier, M-D Tabar, MG Vrhovec, MJ Day, MJ Grigg, P Parola, P Seneviratna, R Killick-Kendrick, RB Kline, RJ Quinnell, RN Davidson, S Carver, S Davies, S Harrus, S Harrus, S Tasker, Scott Carver, SE Shaw, Séverine Tasker, T Bouzouraa, V Pintado, WH Pryor Jr, Y Mekuzas, Y Rosseel   +55 more
core   +6 more sources

Unravelling the biochemical aspects of the interaction between ticks and Leishmania using a tick cell line

Medical and Veterinary Entomology, Volume 40, Issue 2, Page 350-359, June 2026.
Leishmania infantum propagated in IDE8 tick cell line in vitro. L. infantum reduces tick cell viability and induces reactive oxygen species production. Lipidic profile of IDE8 tick cell line is altered during Leishmania infection. Abstract Leishmaniasis comprises a group of vector‐borne neglected tropical diseases caused by species of the obligatory ...
Beatriz Filgueiras Silvestre, Karoline dos Anjos Lima, Fernanda de Paula Pepino, Daniela Cosentino‐Gomes, Adivaldo Fonseca, Lesley Bell‐Sakyi, Georgia Correa Atella, Lucia H. Pinto‐da‐Silva   +7 more
wiley   +1 more source

Tissue Cytokine Responses in Canine Visceral Leishmaniasis [PDF]

, 2001
To elucidate the local tissue cytokine response of dogs infected with Leishmania chagasi, cytokine mRNA levels were measured in bone marrow aspirates from 27 naturally infected dogs from Brazil and were compared with those from 5 uninfected control ...
Courtenay, O., Day, M.J., Dye, C., Garcez, L.M., Kaye, P.M., Quinnell, R.J., Shaw, M.-A.   +6 more
core   +2 more sources

Transmission potential of paromomycin-resistant Leishmania infantum and Leishmania donovani

Journal of Antimicrobial Chemotherapy, 2019
AbstractObjectivesFormer studies demonstrated quick selection of paromomycin resistance for Leishmania infantum and Leishmania donovani accompanied by increased fitness. The present study aimed to interpret these findings in an epidemiological context by comparing infection of WT and experimentally derived paromomycin-resistant strains in the sand fly ...
G Caljon, P Volf, L Maes, J Sadlova, H Aslan, L Van Bockstal, S Hendrickx   +6 more
openaire   +2 more sources

Canine Leishmaniasis in Rio de Janeiro, Brazil (2000–2015): Taxonomic Characterisation of Etiological Agents and Geospatial Case Analysis

Zoonoses and Public Health, Volume 73, Issue 4, Page 314-325, June 2026.
ABSTRACT Introduction Canine Leishmaniasis is a vector‐borne zoonotic disease caused by several species of protozoa of the genus Leishmania. In the state of Rio de Janeiro (RJ), Leishmania braziliensis is the most prevalent species causing tegumentary leishmaniasis (TL) and Leishmania infantum is the main causative agent of visceral leishmaniasis (VL).
Luciana de Freitas Campos Miranda, Laryssa Fabiano do Rosário Coelho, Samanta Cristina das Chagas Xavier, Artur Augusto Velho Mendes Junior, Renan Nunes Albuquerque, Aline Fagundes da Silva, Andreza Pain Marcelino, Fernanda Nunes Santos, Sandro Antonio Pereira, Rodrigo Caldas Menezes, Armando de Oliveira Schubach   +10 more
wiley   +1 more source

Structure of tyrosine aminotransferase fromLeishmania infantum [PDF]

Acta Crystallographica Section F Structural Biology Communications, 2014
The trypanosomatid parasiteLeishmania infantumis the causative agent of visceral leishmaniasis (VL), which is usually fatal unless treated. VL has an incidence of 0.5 million cases every year and is an important opportunistic co-infection in HIV/AIDS. Tyrosine aminotransferase (TAT) has an important role in the metabolism of trypanosomatids, catalyzing
Moreno, M. A., Abramov, A., Abendroth, J., Alonso, A., Zhang, S., Alcolea, P. J., Edwards, T., Lorimer, D., Myler, P. J., Larraga, V.   +9 more
openaire   +3 more sources

Factors Associated With the Emergence and Spread of Visceral Leishmaniasis in the State of São Paulo, Brazil

Zoonoses and Public Health, Volume 73, Issue 4, Page 348-357, June 2026.
ABSTRACT Introduction Visceral leishmaniasis (VL), once considered a rural disease in Brazil, has progressively urbanised, particularly in the state of São Paulo (SSP), where the first urban cases emerged after the detection of the vector Lutzomyia longipalpis in 1997.
Vera Lucia Fonseca de Camargo‐Neves, Guilherme Loureiro Werneck   +1 more
wiley   +1 more source

The recombinant protein rSP03B is a valid antigen for screening dog exposure to Phlebotomus perniciosus across foci of canine leishmaniasis [PDF]

, 2017
The frequency of sandfly-host contacts can be measured by host antibody levels against sandfly salivary proteins. Recombinant salivary proteins are suggested to represent a valid replacement for salivary gland homogenate (SGH); however, it is necessary ...
Alten, Anderson, Bongiorno, Cortes, Cortes, Courtenay, Di Muccio, Drahota, Gradoni, Kostalova, Maia, Maresca, Maroli, Martín-Martín, Oliva, Prates, Ramalho-Ortigão, Rohousova, Rossi, Vlkova, Vlkova, Volf, Volf, Volf   +23 more
core   +3 more sources

Structural basis of secreted acid phosphatase polymerization in the Leishmania parasite

Protein Science, Volume 35, Issue 5, May 2026.
Abstract Enzymes that assemble into filaments typically transition between protomeric and polymeric states in response to cellular conditions. In contrast, the secreted acid phosphatase (SAP) of Leishmania, one of the most abundant extracellular glycoproteins produced by the parasite and regarded as a major virulence factor in the neglected tropical ...
Priyanka Bose, Irit Dahan, Alexander Upcher, Ran Zalk, Iris Grossman‐Haham   +4 more
wiley   +1 more source

Leishmania donovani populations in Eastern Sudan: temporal structuring and a link between human and canine transmission. [PDF]

, 2014
BACKGROUND: Visceral leishmaniasis (VL), caused by the members of the Leishmania donovani complex, has been responsible for devastating VL epidemics in the Sudan.
Baleela, Rania, Fitzpatrick, Sinead, Kuhls, Katrin, Llewellyn, Martin S, Mauricio, Isabel L, Miles, Michael A, Schönian, Gabriele   +6 more
core   +3 more sources