Results 91 to 100 of about 32,531 (219)

Successful Management of Septic Splenitis in an Abyssinian Cat

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
A 3.5‐year‐old female neutered Abyssinian with pyrexia of unknown origin and splenomegaly was diagnosed with septic splenitis. Complete resolution of clinical signs followed splenectomy and antibiotic treatment with pradofloxacin. Septic splenitis, although uncommon, should be considered as a differential diagnosis in patients with splenomegaly and ...
Martina Vecín Sancho, Perrine Henry, Mica Taylor, Catherine Davidson, María Lázaro Muñoz, Efa Llewellyn, Maša Vilfan, Paola Cazzini, Linda Morrison, Kelly Blacklock, Danièlle Gunn‐Moore   +10 more
wiley   +1 more source

Acute febrile illness is associated with Rickettsia spp infection in dogs [PDF]

, 2015
BACKGROUND: Rickettsia conorii is transmitted by Rhipicephalus sanguineus ticks and causes Mediterranean Spotted Fever (MSF) in humans. Although dogs are considered the natural host of the vector, the clinical and epidemiological significance of R ...
A Cascio, A Estrada-Pena, A Mannelli, A Mura, A Ortuno, A Rojas, A Torina, A Torina, A Torina, A Znazen, Alessandra Caprì, AM Gasser, BA Stillman, C Colomba, C Riera, C Rovery, CP Ober, D Otranto, D Otranto, D Otranto, E Beeler, E Sanger, EB Breitschwerdt, F Segura-Porta, FJ Marquez, G Baneth, G Baneth, G Baneth, G Vitale, GB Andrade, GM Giammanco, GM Giammanco, H Inokuma, J Fuente de la, JC Garcia-Garcia, L Solano-Gallego, L Solano-Gallego, L Solano-Gallego, L Solano-Gallego, L Solano-Gallego, L Solano-Gallego, L Solano-Gallego, Laia Solano-Gallego, M Bernabeu-Wittel, M Rene-Martellet, M Sarih, Marco Caldin, Maria Grazia Pennisi, ME Eremeeva, ME Mylonakis, Michele Trotta, ML Levin, ML Levin, N Alexandre, N Cardenosa, NY Salem, P Brouqui, P Brouqui, P Parola, P Parola, PJ Kelly, S Delgado, S Harrus, S Harrus, S Santibanez, SE Little, T Beninati, T Furlanello, Tommaso Furlanello, WL Nicholson   +69 more
core   +3 more sources

Safety, tolerability and pharmacokinetics of DNDI‐6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants

British Journal of Clinical Pharmacology, Volume 92, Issue 4, Page 1087-1097, April 2026.
Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon, Sophie Delhomme, Delphine Launay, Séverine Blesson, Stéphanie Braillard, Pegah Maghdooni, Frauke Assmus, Richard Hoglund, Joel Tarning, Sabrina Loyau, Byron Arana, Mathilde Latreille‐Barbier, Yves Donazzolo   +12 more
wiley   +1 more source

Molecular variation in Leishmania parasites from sandflies species of a zoonotic cutaneous leishmaniasis in northeast of Iran [PDF]

, 2014
Background & objectives: In the well-known zoonotic cutaneous leishmaniasis (ZCL) focus in Turkmen Sahara, border of Iran and Turkmenistan, ZCL has increased among humans in the past five years.
Parvizi, P., Roshanghalb, M., Sharbatkhori, M., Spotin, A., Taherkhani, H.   +4 more
core  

Brain Involvement in Leishmaniasis

Cell Biochemistry and Function, Volume 44, Issue 4, April 2026.
ABSTRACT Leishmaniasis is a neglected tropical disease caused by infection with the protozoan parasite Leishmania and it is a significant global health problem. The disease has a wide clinical spectrum, from tegumentary leishmaniasis (TL) that encompasses cutaneous (CL), mucosal (ML) and cutaneous‐diffuse (CDL) forms, to the potentially fatal systemic ...
Camila S. Freitas, Eduardo A. F. Coelho, Myron Christodoulides   +2 more
wiley   +1 more source

In Vitro Screening Test Using Leishmania Promastigotes Stably Expressing mCherry Protein [PDF]

, 2014
Transgenic Leishmania major and Leishmania donovani axenic promastigotes constitutively expressing mCherry were used for in vitro antileishmanial drug screening. This method requires minimal sample manipulation and can be easily adapted to automatic drug
Miguel A. Morales, Vacchina, Paola
core   +2 more sources

Leishmania Extracellular Vesicles as a Preventive Vaccine Platform Against Leishmaniasis

Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
The potential of Leishmania‐derived extracellular vesicles (EVs) as a vaccine platform was investigated, emphasizing an affordable, GMP‐compliant production and purification method. Immunization with EV vaccines, either unadjuvanted or combined with α‐galactosylceramide (αGC), induced robust humoral and cellular immune responses, conferring protection ...
Ismail Cem Yilmaz, Ibrahim Tokmak, Muzaffer Yildirim, Tugce Canavar Yildirim, Elif Sena Ozkoc, Irem Evcili, Emre Mert Ipekoglu, İhsan Cihan Ayanoglu, Emre Dunuroglu, Dicle Caliskan, Harun Onler, Zeynep Arzum, Ceren Ulker, Olcay Mert, Ridvan Orkut, Ibrahim Oguzhan Tarman, Ulku Guler, Bekir Salih, Volkan Yazar, Gokcen Ozgun, Serap Birincioglu, Ahmet Ozbilgin, Bilgi Gungor, Ihsan Gursel, Mayda Gursel   +24 more
wiley   +1 more source

Leishmania infection in cats and dogs housed together in an animal shelter reveals a higher parasite load in infected dogs despite a greater seroprevalence among cats

Parasites & Vectors, 2020
Background An outbreak of leishmaniosis was studied in cats and dogs housed together with no separation in an animal shelter in Israel. Methods The study included recording of clinical signs, serology for Leishmania infection by ELISA, PCR of blood for ...
Gad Baneth, Yaarit Nachum-Biala, Adam Zuberi, Nirit Zipori-Barki, Laor Orshan, Gabriela Kleinerman, Ayelet Shmueli-Goldin, Michel Bellaiche, Monica Leszkowicz-Mazuz, Harold Salant, Daniel Yasur-Landau   +10 more
doaj   +1 more source

Risk factors for visceral leishmaniasis in a new epidemic site in Amhara Region, Ethiopia [PDF]

, 2009
We conducted a case-control study to evaluate risk factors for visceral leishmaniasis during an epidemic in a previously unaffected district of Ethiopia. We also collected blood and bone marrow specimens from dogs in the outbreak villages.
Alvar, Jorge, Aparicio, Pilar, Argaw, Daniel, Bashaye, Seife, Bern, Caryn, Cañavate, Carmen, Chicharro, Carmen, Herrero, Merce, Mulugeta, Abate, Nieto, Javier, Nombela, Nohelly, Vélez, Iván Darío   +11 more
core   +1 more source

Visceral leishmaniasis patients display altered composition and maturity of neutrophils as well as impaired neutrophil effector functions [PDF]

, 2016
Immunologically, active visceral leishmaniasis (VL) is characterised by profound immunosuppression, severe systemic inflammatory responses and an impaired capacity to control parasite replication.
Adem, E, Cruz Cervera, E, Diro, E, Getahun, M, Hailu, A, Kropf, P, Lemma, M, Melkamu, R, Mengesha, B, Mesfin, G, Modolell, M, Muller, I, Munder, M, Skhedy, Z, Tajebe, F, Takele, Y, Van der Auwera, G, Yardley, V, Yeshanew, A, Yizengaw, E   +19 more
core   +3 more sources