Results 101 to 110 of about 32,531 (219)

Comprehensive Analysis of Structure Activity Relationships in Quinoxaline Derivatives Covering Antimicrobial Applications

ChemistrySelect, Volume 11, Issue 14, 13 April 2026.
ABSTRACT Antimicrobial resistance (AMR) has emerged as one of the most critical global health challenges, undermining the clinical efficacy of existing antibiotics and threatening modern therapeutic strategies. The ongoing misuse and overuse of antimicrobial agents have accelerated the evolution of resistant bacterial strains and parasites ...
Subham Kumar Vishwakarma, Fernando Rogério Pavan, Cesar Augusto Roque‐Borda   +2 more
wiley   +1 more source

Natural infection of Didelphis aurita (Mammalia: Marsupialia) with Leishmania infantum in Brazil

Parasites & Vectors, 2012
Background The opossum Didelphis have been considered as natural hosts of Leishmania parasites in the New World, suggesting an important role in the epidemiology of Visceral Leishmaniasis (VL). Among six extant species that belong to the genus Didelphis,
Carreira João Carlos, da Silva Alba Valéria, de Pita Pereira Daniela, Brazil Reginaldo   +3 more
doaj   +1 more source

Synthesis and Evaluation of the First Generation of Glycosylated Nucleoside Analogues as Potential Inhibitors of the Base J Metabolism in Kinetoplastid Parasites

Chemistry – A European Journal, Volume 32, Issue 10, 9 March 2026.
Novel analogues of the kinetoplastid‐specific DNA base J unlock a new way to target parasite epigenetic regulation. Some compounds selectively inhibit Leishmania and Trypanosoma species without harming human cells, revealing a promising route toward innovative antiparasitic therapies.
Océane Monfret, Dan Liu, Manon Louis, Sihem Rebei, Dominique Urban, Yann Bourdreux, Elisabeth Mouray, Philippe Grellier, Gilles Doisneau, Dominique Guianvarc'h   +9 more
wiley   +1 more source

Hybridization in parasites: consequences for adaptive evolution, pathogenesis and public health in a changing world [PDF]

, 2015
[No abstract ...
A Berry, A Koukounari, AJ Norton, AR Laird, B Schelkle, BL Webster, BL Webster, BL Webster, BR Grant, C Astrom, C Gyles, CA Machado, CD Criscione, CM Brasier, CM Lively, CM Lively, CS Clarkson, CS Wondji, D Menge, D Rollinson, D Weetman, DB Dunams-Morel, DE Neafsey, Deborah F. Smith, DR Brooks, DR Dittrich-Reed, E Inbar, E Mancini, E Redman, E Strauch, EH Stukenbrock, EJ Baack, GL Nichols, Glenn F Rall, H Krehenwinkel, H Ochman, H Ochman, HD Mawejje, HJ Müller, HV Pates, I Goodhead, J Boissier, J Davies, J Hawks, J Mallet, J Mavarez, JA Coyne, JA Patz, JC Semenza, JM Kelly, Joanne P. Webster, JP Webster, JP Webster, JT Detwiler, Kayla C. King, KD Lafferty, LA Messenger, LA Messenger, LAT Tchuente, LC Norris, LH Rieseberg, LH Rieseberg, M Arnold, M Lynch, M Schumer, M Worobey, MA Miles, MA Nowak, MB Rogers, MB Rogers, MC Fontaine, ME Grigg, MF Dybdahl, MG Taylor, Michael A. Brockhurst, MJ Gibbs, ML Arnold, ML Arnold, ML Steinauer, MW Gaunt, NH Barton, NR Sturm, NS Akopyants, O Seehausen, P Martens, P Volf, P Volf, PW Hedrick, R Abbott, RA Farrer, RB Stelkens, RB Stelkens, RDH Barrett, Rike B. Stelkens, RS Ramiro, S Edmands, S Hales, S Manguin, S Moore, T Dobzhansky, T Huyse, T Huyse, TH Le, U Chaudhry, W Alves, W Choochote, W Li, Y Lee, Y Song   +108 more
core   +2 more sources

Leishmania infantum

, 2018
El Atlas Comentado sobre Protozoología presenta imágenes que pertenecen a protozoos parásitos que con mayor frecuencia se diagnostican en la región por parte de los equipos de docentes-investigadores pertenecientes al Centro de Estudios Parasitológicos y de Vectores (CEPAVE-CONICET-UNLP) y al Laboratorio de Inmunoparasitología (LAINPA-FCV-UNLP).
Dellarupe, Andrea, Eiras, Diego Fernando, Venturini, María Cecilia   +2 more
openaire   +1 more source

Exploring Novel Nitrofuryl‐1,3,4‐Thiadiazole‐Based Derivatives: Design, Synthesis, and Evaluation of In Vitro Leishmanicidal and Trypanocidal Activity

Archiv der Pharmazie, Volume 359, Issue 3, March 2026.
In a series of substituted 1‐[5‐(5‐nitrofuran‐2‐yl)‐1,3,4‐thiadiazol‐2‐yl]piperidine‐4‐carboxamides evaluated for in vitro antileishmanial and antitrypanosomal activity, compound 18 emerged as the most promising derivative, showing submicromolar anti‐parasitic effects targeting diverse Leishmania and Trypanosoma species and acceptable selectivity ...
Alireza Mousavi, Martina Slapničková, Maryam Norouzbahari, Sarah D'Alessandro, Parham Foroumadi, Fariba Peytam, Federica Perego, Eva Doleželová, Zahra Emamgholipour, Maliheh Barazandeh Tehrani, Seyed Esmaeil Sadat‐Ebrahimi, Elahe Hosseinzadeh, Elmira Meghrazi Ahadi, Loghman Firoozpour, Hamidreza Bijanzadeh, Nicoletta Basilico, Alena Zíková, Alireza Foroumadi   +17 more
wiley   +1 more source

Unusual report of an immunocompetent patient with atypical cutaneous leishmaniasis caused by Leishmania (Leishmania) infantum in Minas Gerais, Brazil [PDF]

Revista da Sociedade Brasileira de Medicina Tropical
Cutaneous leishmaniasis is endemic in Minas Gerais, Brazil; however, data on the circulating species remain limited. This study identified Leishmania species in he skin samples of patients in Montes Claros using molecular methods.
Rebeca Mendes Rocha, Jackeline Maria de Sousa Lima Lopes, Emanuelle de Moura Santos Xavier, Rosanna Lorrane Francisco dos Reis Matos, Dayse Marcielle de Souza Lopes, Flávia Carvalho Bitencourt de Oliveira, Felipe Dutra Rêgo, José Dilermando Andrade, Célia Maria Ferreira Gontijo, Leandro de Freitas Teles, Jamille Fernandes Lula, Luciano Freitas Fernandes, André Luiz Sena Guimarães, Ana Paula Venuto Moura, Thallyta Maria Vieira, Sílvio Fernando Guimarães de Carvalho   +15 more
doaj   +1 more source

A neglected disease of humans: a new focus of visceral leishmaniasis in Bakool, Somalia. [PDF]

, 2008
Visceral leishmaniasis (VL) was observed in children in Bakool region, Somalia, an area where VL has not been reported before. We describe the extent of the problem in this war- and famine-stricken area.
Boelaert, M, Dujardin, J C, Jacquet, D, Marlet, M V L, Quispe, K W, Wuillaume, F   +5 more
core   +1 more source

The Role of Cytoplasmic mRNA Cap-Binding Protein Complexes in Trypanosoma brucei and Other Trypanosomatids. [PDF]

, 2017
Trypanosomatid protozoa are unusual eukaryotes that are well known for having unusual ways of controlling their gene expression. The lack of a refined mode of transcriptional control in these organisms is compensated by several post-transcriptional ...
Campbell, David A, de Melo Neto, Osvaldo P, Freire, Eden R, Sturm, Nancy R   +3 more
core   +2 more sources

Leishmania tarentolae: taxonomic classification and its application as a promising biotechnological expression host

, 2019
In this review, we summarize the current knowledge concerning the eukaryotic protozoan parasite Leishmania tarentolae, with a main focus on its potential for biotechnological applications.
Klatt, S., Konthur, Z., Maslov, D., Simpson, L.   +3 more
core   +1 more source