Possibility of re-purposing antifungal drugs posaconazole & isavuconazole against promastigote form of Leishmania major. [PDF]
Bhusal CK +6 more
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Dogs may carry Leishmania tropica and Leishmania major in their blood circulation: a molecular and hematological study. [PDF]
Rezaei A +4 more
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Genomic Insights into the Phosphatidylinositol-Specific Phospholipase C Gene Family in <i>Leishmania major</i> and <i>Leishmania infantum</i>: Expression Patterns and Potential Association with Drug Resistance. [PDF]
Sirekbasan S, Osman SS, Gürkök-Tan T.
europepmc +1 more source
Characterisation of ATR kinase mutants in Leishmania major.
Gabriel L. A. da Silva (22676649) +5 more
openalex +1 more source
A New Immunogenic Structure of Polyepitopic Fusion against Leishmania major: In Silico Study. [PDF]
Pirmoradi S +4 more
europepmc +1 more source
ATR, a DNA damage kinase, modulates DNA replication timing in Leishmania major
da Silva GLA +4 more
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The Regulation of Immunity to Leishmania Major
Annual Review of Immunology, 1995Experimental infection with the intracellular protozoan Leishmania major constitutes a particularly versatile model for assessing the role of CD4+ subset development in the host response to infectious disease. The association of Th1 development with control of infection, and of Th2 cell development with progressive disease, has been well established ...
S L, Reiner, R M, Locksley
openaire +3 more sources
Folylpolyglutamates in Leishmania major
Biochemical and Biophysical Research Communications, 1987The intracellular folates of the protozoan parasite Leishmania major have been examined. About 95% of the exogenous [3H]folate accumulated by the protozoan is metabolized to polyglutamate conjugates within 65 hr, and the intracellular folates are about forty-fold concentrated over the folate in the medium.
D V, Santi, P, Nolan, B, Shane
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Trypanothione biosynthesis in Leishmania major
Molecular and Biochemical Parasitology, 2005Trypanothione plays a crucial role in regulation of intracellular thiol redox balance and in defence against chemical and oxidant stress. Crithidia fasciculata requires two enzymes for the formation of trypanothione, namely glutathionylspermidine synthetase (GspS; EC 6.3.1.8) and a glutathionylspermidine-dependent trypanothione synthetase (TryS; EC 6.3.
Oza, Sandra L. +3 more
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