Results 241 to 250 of about 76,622 (282)
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Leishmania major infection: the overture
Parasitology Today, 1995Local infection of mice with Leishmania major results in either healing or death depending on the preferential action of Th1 or Th2 T helper cells, respectively. Although the parasite-induced T-cell responses and their consequences for the disease are well understood, relatively little is known about the initial events that kindle the adaptive immune ...
W, Solbach, T, Laskay
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Brazilian Leishmania Stocks Phenotypically Similar to Leishmania Major
The American Journal of Tropical Medicine and Hygiene, 1985Screening by enzyme electrophoresis of isolates of New World Leishmania from different geographic areas revealed a number of stocks with enzyme profiles different from those produced by reference strains of described subspecies of L. mexicana, L. braziliensis, and L. donovani.
H, Momen +5 more
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The emergence of Leishmania major and Leishmania donovani in southern Turkey
Transactions of the Royal Society of Tropical Medicine and Hygiene, 2014In southern Turkey, Leishmania tropica and L. infantum are both the causative agents of cutaneous leishmaniasis (CL) and visceral leishmaniasis (VL), respectively. However, L. major and L. donovani were known to exist after the influx of Syrian refugees.Between the years of July 2003 and July 2013, a total of 167 smears and 113 bone marrow samples were
Koltas I.S. +3 more
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Extracellular phosphorylation in the parasite, Leishmania major
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1990Leishmania major promastigotes were analyzed for the presence of protein phosphatase activity in intact cells and membrane-enriched fractions. Parasite phosphoproteins, phosphorylated in live cells with [gamma-32P]adenosine 5'-triphosphate (ATP) and an endogenous leishmanial ectokinase, were dephosphorylated by endogenous protein phosphatase-like ...
D S, Lester, T, Hermoso, C L, Jaffe
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Ubiquinone biosynthesis in Leishmania major promastigotes
International Journal for Parasitology, 1995Promastigotes of Leishmania major contain a ubiquinone which has a side chain made up of nine isoprene subunits (UQ9). Incorporation of radioactivity from [14C] acetate and [14C] mevalonate into ubiquinone as well as the identification of hydroxymethylglutaryl coenzyme A reductase (HMG CoA reductase), and mevalonate kinase indicate that the isoprenoid ...
G, Ranganathan, A J, Mukkada
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Leishmania infantum and L. major in Algeria
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1996Since 1980, the development of leishmaniasis in Algeria has been marked by a considerable increase in the number of cases of both visceral leishmaniasis (1121 cases recorded) and cutaneous leishmaniasis (more than 2000 cases per year). New Leishmania infantum and L. major foci have appeared in the north and south of the country. During this period, 100
Z, Harrat +7 more
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The control of Leishmania (Leishmania) major by TNF in vivo is dependent on the parasite strain
Microbes and Infection, 2004Previous studies provided evidence that the role of TNF in the control of Leishmania (Leishmania) major might vary with the parasite strain. Here, we analyzed the development and outcome of cutaneous leishmaniasis in C57BL/6 wild-type (B6.WT) and TNF-deficient (B6. TNF(-/-)) mice infected with two different isolates of L. (L.) major (FRIEDLIN vs. BNI).
Ritter, Uwe +4 more
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Population structure of leishmania major in southeastern morocco
Acta Tropica, 2020Cutaneous leishmaniasis (CL) is an infectious disease caused by various Leishmania species. It is among the most neglected tropical diseases and has been considered a major health threat over the past decades in the country. Its zoonotic form caused by Leishmania (L) major is the most prevalent in Morocco.
Mouad, Ait Kbaich +6 more
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Leishmania mexicana and Leishmania tropica major: Adoptive transfer of immunity in mice
Experimental Parasitology, 1980Abstract The transfer of lymphocytes from NIH mice infected with Leishmania tropica major to nonimmune syngeneic mice, which had received 600 rad irradiation, markedly altered the course of subsequent Leishmania mexicana and L.t. major infections in these animals, when compared with infections in irradiated mice reconstituted with lymphocytes ...
J, Alexander, R S, Phillips
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Leishmanicidal and apoptotic activities of oleuropein on Leishmania major
Int. Journal of Clinical Pharmacology and Therapeutics, 2014Leishmania is a unicellular protozoan parasite causing a wide range of human diseases ranging from localized self-healing cutaneous lesions to fatal visceral infections.The aim of the present study is to assess the cytotoxic, anti-proliferative, and apoptotic effects of oleuropein on Leishmania major promastigotes (MHOM/SA/84/JISH) and to compare its ...
Maha H, Elamin, Salyha S, AL-Maliki
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