Results 21 to 30 of about 17,699 (240)

Role of higher levels of post-challenge antibodies in protective vaccination against Leishmania tropica infection of BALB/c mice

Asian Pacific Journal of Tropical Biomedicine, 2020
Objective: To study the role of antibodies in protection against Leishmania tropica (L. tropica) infection in the experimental model of BALB/c mice. Methods: BALB/c mice were vaccinated against L.
Mosayeb Rostamian, Hamid M Niknam
doaj   +1 more source

Genetic structure and evolution of the Leishmania genus in Africa and Eurasia: what does MLSA tell us [PDF]

, 2013
Leishmaniasis is a complex parasitic disease from a taxonomic, clinical and epidemiological point of view. The role of genetic exchanges has been questioned for over twenty years and their recent experimental demonstration along with the identification ...
Berry, Vincent, Brisse, Sylvain, Chevenet, François, Diancourt, Laure, El Baidouri, Fouad, Marty, Pierre, Pratlong, Francine, Ravel, Christophe   +7 more
core   +7 more sources

Investigating the antiparasitic potential of the marine sesquiterpene avarone, its reduced form avarol, and the novel semisynthetic thiazinoquinone analogue thiazoavarone [PDF]

, 2020
The chemical analysis of the sponge Dysidea avara afforded the known sesquiterpene quinone avarone, along with its reduced form avarol. To further explore the role of the thiazinoquinone scaffold as an antiplasmodial, antileishmanial and antischistosomal
AIELLO, ANNA, Avunduk, Sibel, Basilico, Nicoletta, CASERTANO, MARCELLO, FATTORUSSO, CATERINA, Gimmelli, Roberto, Guidi, Alessandra, IMPERATORE, CONCETTA, LUCIANO, PAOLO, MENNA, MARIALUISA, Parapini, Silvia, PERSICO, MARCO, Ruberti, Giovina, Saccoccia, Fulvio   +13 more
core   +1 more source

Assessment of in vitro and in vivo effect of Quercetin 3-Glucoside, Oxyresveratrol and Quercetin O-Hexoside against Leishmania tropica

Brazilian Journal of Pharmaceutical Sciences, 2023
The aim was to scrutinize the in vivo and in vitro activities against Leishmania tropica with compounds of Oxyresveratrol, Quercetin O-Hexoside, and Quercetin 3-Glucoside.
Kashif Iqbal, Saba Noor, Akram Shah, Adnan Amin   +3 more
doaj   +1 more source

Predominance of Leishmania major and rare occurrence of Leishmania tropica with haplotype variability at the center of Iran

Brazilian Journal of Infectious Diseases, 2018
Background: Leishmania major is a causative agent of zoonotic cutaneous leishmaniasis in the center of Iran, Abarkouh district. Molecular characterization and precise incrimination of Leishmania species was carried out to perform controlling measurements
Amir Hossein Zahirnia, Ali Bordbar, Sahar Ebrahimi, Adel Spotin, Somayeh Mohammadi, Seyedeh Maryam Ghafari, Setareh Ahmadvand, Negar Jabbari, Ahmad Reza Esmaeili Rastaghi, Parviz Parvizi   +9 more
doaj   +3 more sources

Lower levels of IgG1 in comparison with IgG2a are associated with protective immunity against Leishmania tropica infection in BALB/c mice

Journal of Microbiology, Immunology and Infection, 2017
Leishmania (L.) tropica is the causative agent of different forms of human leishmaniasis. There is little information about the role of Leishmania-specific antibodies in the immune response against L. tropica infection.
Mosayeb Rostamian, Saeed Sohrabi, Hanie Kavosifard, Hamid M. Niknam   +3 more
doaj   +1 more source

Gene expression in Leishmania is regulated predominantly by gene dosage [PDF]

, 2017
Leishmania tropica, a unicellular eukaryotic parasite present in North and East Africa, the Middle East, and the Indian subcontinent, has been linked to large outbreaks of cutaneous leishmaniasis in displaced populations in Iraq, Jordan, and Syria. Here,
Berriman, Matthew, Beverley, Stephen M., Cotton, James A., Durrant, Caroline, Grigg, Michael E., Iantorno, Stefano A., Khan, Asis, Myler, Peter, Ouellette, Marc, Sacks, David L., Sanders, Mandy J., Warren, Wesley C., Weiss, Louis M.   +12 more
core   +3 more sources

Herbal extract targets in Leishmania tropica [PDF]

Journal of Parasitic Diseases, 2014
The present study aims to investigate the effect of some herbal extract such as phenolic compounds on the viability of Leishmania tropica promastigotes in vitro. Four tested chemical agents (caffeic acid (CA), ferulic acid (FA), syringic acid (SA) and 4-hydroxybenzoic acid (4-HBA)) were used in this study.
Bassim I, Mohammad, Maani N, Al Shammary, Roaa H, Abdul Mageed, Nasser Ghaly, Yousif   +3 more
openaire   +2 more sources

Changes in the Epidemiology of Cutaneous Leishmaniasis in Northeastern Iran

Türkiye Parazitoloji Dergisi, 2020
The province of Khorasan-Razavi in the North East of Iran is an endemic area for anthroponotic cutaneous leishmaniasis (ACL caused mainly by Leishmania tropica) and zoonotic cutaneous leishmaniasis (ZCL caused mainly by Leishmania major).
Bibi Razieh Hosseini Farash, Seyed Ali Akbar Shamsian, Masoud Mohajery, Abdolmajid Fata, Fatemeh Sadabadi, Fariba Berenji, Pietro Mastroeni, Elham Poustchi, Elham Moghaddas, Ghodratollah Salehi Sangani, Gholamreza Farnoosh   +10 more
doaj   +1 more source

Vaccination with whole-cell killed or recombinant leishmanial protein and toll-like receptor agonists against Leishmania tropica in BALB/c mice. [PDF]

PLoS ONE, 2018
One strategy to control leishmaniasis is vaccination with potent antigens alongside suitable adjuvants. The use of toll-like receptor (TLR) agonists as adjuvants is a promising approach in Leishmania vaccine research. Leishmania (L.) tropica is among the
Mosayeb Rostamian, Fariborz Bahrami, Hamid M Niknam   +2 more
doaj   +1 more source