Results 21 to 30 of about 17,806 (239)

Investigating the antiparasitic potential of the marine sesquiterpene avarone, its reduced form avarol, and the novel semisynthetic thiazinoquinone analogue thiazoavarone [PDF]

, 2020
The chemical analysis of the sponge Dysidea avara afforded the known sesquiterpene quinone avarone, along with its reduced form avarol. To further explore the role of the thiazinoquinone scaffold as an antiplasmodial, antileishmanial and antischistosomal
AIELLO, ANNA, Avunduk, Sibel, Basilico, Nicoletta, CASERTANO, MARCELLO, FATTORUSSO, CATERINA, Gimmelli, Roberto, Guidi, Alessandra, IMPERATORE, CONCETTA, LUCIANO, PAOLO, MENNA, MARIALUISA, Parapini, Silvia, PERSICO, MARCO, Ruberti, Giovina, Saccoccia, Fulvio   +13 more
core   +1 more source

Herbal extract targets in Leishmania tropica [PDF]

Journal of Parasitic Diseases, 2014
The present study aims to investigate the effect of some herbal extract such as phenolic compounds on the viability of Leishmania tropica promastigotes in vitro. Four tested chemical agents (caffeic acid (CA), ferulic acid (FA), syringic acid (SA) and 4-hydroxybenzoic acid (4-HBA)) were used in this study.
Bassim I, Mohammad, Maani N, Al Shammary, Roaa H, Abdul Mageed, Nasser Ghaly, Yousif   +3 more
openaire   +2 more sources

Predominance of Leishmania major and rare occurrence of Leishmania tropica with haplotype variability at the center of Iran

Brazilian Journal of Infectious Diseases, 2018
Background: Leishmania major is a causative agent of zoonotic cutaneous leishmaniasis in the center of Iran, Abarkouh district. Molecular characterization and precise incrimination of Leishmania species was carried out to perform controlling measurements
Amir Hossein Zahirnia, Ali Bordbar, Sahar Ebrahimi, Adel Spotin, Somayeh Mohammadi, Seyedeh Maryam Ghafari, Setareh Ahmadvand, Negar Jabbari, Ahmad Reza Esmaeili Rastaghi, Parviz Parvizi   +9 more
doaj   +3 more sources

Lower levels of IgG1 in comparison with IgG2a are associated with protective immunity against Leishmania tropica infection in BALB/c mice

Journal of Microbiology, Immunology and Infection, 2017
Leishmania (L.) tropica is the causative agent of different forms of human leishmaniasis. There is little information about the role of Leishmania-specific antibodies in the immune response against L. tropica infection.
Mosayeb Rostamian, Saeed Sohrabi, Hanie Kavosifard, Hamid M. Niknam   +3 more
doaj   +1 more source

Wildlife as a Sentinel for Pathogen Introduction in Nonendemic Areas: First Detection of <i>Leishmania tropica</i> in Wildlife in Spain. [PDF]

Transbound Emerg Dis
Azami-Conesa I, Matas Méndez P, Pérez-Moreno P, Carrión J, Alunda JM, Mateo Barrientos M, Gómez-Muñoz MT.   +6 more
europepmc   +3 more sources

Gene expression in Leishmania is regulated predominantly by gene dosage [PDF]

, 2017
Leishmania tropica, a unicellular eukaryotic parasite present in North and East Africa, the Middle East, and the Indian subcontinent, has been linked to large outbreaks of cutaneous leishmaniasis in displaced populations in Iraq, Jordan, and Syria. Here,
Berriman, Matthew, Beverley, Stephen M., Cotton, James A., Durrant, Caroline, Grigg, Michael E., Iantorno, Stefano A., Khan, Asis, Myler, Peter, Ouellette, Marc, Sacks, David L., Sanders, Mandy J., Warren, Wesley C., Weiss, Louis M.   +12 more
core   +3 more sources

Changes in the Epidemiology of Cutaneous Leishmaniasis in Northeastern Iran

Türkiye Parazitoloji Dergisi, 2020
The province of Khorasan-Razavi in the North East of Iran is an endemic area for anthroponotic cutaneous leishmaniasis (ACL caused mainly by Leishmania tropica) and zoonotic cutaneous leishmaniasis (ZCL caused mainly by Leishmania major).
Bibi Razieh Hosseini Farash, Seyed Ali Akbar Shamsian, Masoud Mohajery, Abdolmajid Fata, Fatemeh Sadabadi, Fariba Berenji, Pietro Mastroeni, Elham Poustchi, Elham Moghaddas, Ghodratollah Salehi Sangani, Gholamreza Farnoosh   +10 more
doaj   +1 more source

Vaccination with whole-cell killed or recombinant leishmanial protein and toll-like receptor agonists against Leishmania tropica in BALB/c mice. [PDF]

PLoS ONE, 2018
One strategy to control leishmaniasis is vaccination with potent antigens alongside suitable adjuvants. The use of toll-like receptor (TLR) agonists as adjuvants is a promising approach in Leishmania vaccine research. Leishmania (L.) tropica is among the
Mosayeb Rostamian, Fariborz Bahrami, Hamid M Niknam   +2 more
doaj   +1 more source

Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism. [PDF]

, 1990
BALB/c mice infected with Leishmania major develop fatal, progressive disease, despite an immune response characterized by expansion of CD4+ T cells in the draining lymph nodes.
Dawkins, RS, Heinzel, FP, Holaday, BJ, Locksley, RM, Pu, RT, Sadick, MD   +5 more
core   +1 more source

Treatment outcome of imported cutaneous leishmaniasis among travelers and migrants infected with Leishmania major and Leishmania tropica: a retrospective study in European centers 2013 to 2019

International Journal of Infectious Diseases, 2022
: Objectives: Cutaneous leishmaniasis (CL) in Asia, Northern, and Sub-Saharan Africa is mainly caused by Leishmania major and Leishmania tropica. We describe and evaluate the treatment outcome of CL among travelers and migrants in Europe.
Hedvig Glans, Leif Dotevall, Gert Van der Auwera, Aldert Bart, Johannes Blum, Pierre Buffet, Romain Guery, Jean-Pierre Gangneux, Saskia van Henten, Gundel Harms, Stefania Varani, Florence Robert-Gangneux, Robert Rongisch, Björn Andersson, Maria Bradley   +14 more
doaj   +1 more source