Results 41 to 50 of about 68,163 (199)
Genetic diversity of Leishmania tropica: Unexpectedly complex distribution pattern
In this study, we characterized a collection of clinical samples obtained from Syrian and Turkish patients with cutaneous leishmaniasis using internal transcribed spacer 1 (ITS1) sequences. All obtained sequences belonged to Leishmania tropica. Combining
Kostygov, Alexei Yu +15 more
core +1 more source
Evolutionary history of Leishmania killicki (synonymous Leishmania tropica) and taxonomic implications [PDF]
Background: The taxonomic status of Leishmania (L.) killicki, a parasite that causes chronic cutaneous leishmaniasis, is not well defined yet. Indeed, some researchers suggested that this taxon could be included in the L.
Jaouadi, K. +35 more
core +4 more sources
Some parameters for advancement of Leishmania tropica infection were examined in three groups of golden hamsters, Group (1) inoculated with autoclaved killed Leishmania tropica , Group (2) inoculated with BCG vaccine alone while Group (3) Inoculated with
Baghdad Science Journal
doaj +1 more source
Objective: To develop a low-cost, in-house conventional polymerase chain reaction method for leishmania tropica for epidemiological surveillance of disease.
Haroon Ur Rashid +5 more
doaj +1 more source
Coumarin‐Benzimidazole Hybrids as Multitarget Scaffolds for Antileishmanial Drug Discovery
Coumarin‐benzimidazole hybrids emerge as promising antileishmanial agents through virtual screening against essential Leishmania enzymes, Cathepsin B (CatB), and N‐myristoyltransferase (NMT). Molecular docking and dynamics simulations reveal highly stable target interactions that surpass the reference drug miltefosine (MTF).
Fernanda Melo Jucá +4 more
wiley +1 more source
Antibacterial activity of CNSs against Staphylococcus aureus and Escherichia coli was estimated. Higher inhibition zone of 18 mm and 20 mm were observed against S.
Ali Taha +3 more
doaj +1 more source
New anthranilate–naphthoquinone hybrids display potent inhibition of Leishmania (L.) amazonensis with low host cell toxicity. Molecular docking reveals key interactions with TR, GP63, and PTR1, suggesting a multitarget mechanism that contributes to parasite death.
Eduardo Miranda da Silva Magesfeste +7 more
wiley +1 more source
This study investigated the epidemiology, risk factors and spatial distribution of cutaneous leishmaniasis in District Bajaur, Pakistan. Higher prevalence was observed among young males during summer, with lesions mainly on exposed body parts. Spatial analysis identified Khar, Loe Mamund and Salarzai as hotspots, highlighting the need for targeted ...
Murad Ali Khan +10 more
wiley +1 more source
Cutaneous leishmaniasis in Syria is caused mainly by Leishmania tropica. It represents a serious health problem, which has aggravated further after the civil war in the country.
Mohammad Maarouf, Alyaa A. Abdlwahab
doaj +1 more source
Transcriptional signatures in human macrophage-like cells infected by Leishmania infantum, Leishmania major and Leishmania tropica. [PDF]
Background: In the Mediterranean basin, three Leishmania species have been identified: L. infantum, L. major and L. tropica, causing zoonotic visceral leishmaniasis (VL), zoonotic cutaneous leishmaniasis (CL) and anthroponotic CL, respectively.
Diotallevi A +10 more
europepmc +2 more sources

