Results 41 to 50 of about 68,163 (199)

Genetic diversity of Leishmania tropica: Unexpectedly complex distribution pattern

open access: yes, 2021
In this study, we characterized a collection of clinical samples obtained from Syrian and Turkish patients with cutaneous leishmaniasis using internal transcribed spacer 1 (ITS1) sequences. All obtained sequences belonged to Leishmania tropica. Combining
Kostygov, Alexei Yu   +15 more
core   +1 more source

Evolutionary history of Leishmania killicki (synonymous Leishmania tropica) and taxonomic implications [PDF]

open access: yes, 2015
Background: The taxonomic status of Leishmania (L.) killicki, a parasite that causes chronic cutaneous leishmaniasis, is not well defined yet. Indeed, some researchers suggested that this taxon could be included in the L.
Jaouadi, K.   +35 more
core   +4 more sources

The follow up of experimentally infected hamsters with Leishmania tropica immunized with different vaccines

open access: yesمجلة بغداد للعلوم, 2007
Some parameters for advancement of Leishmania tropica infection were examined in three groups of golden hamsters, Group (1) inoculated with autoclaved killed Leishmania tropica , Group (2) inoculated with BCG vaccine alone while Group (3) Inoculated with
Baghdad Science Journal
doaj   +1 more source

Determination of frequency of Leishmania tropica in laboratory-confirmed cases of cutaneous leishmaniasis using an in-house conventional PCR test

open access: yesJournal of the Pakistan Medical Association
Objective: To develop a low-cost, in-house conventional polymerase chain reaction method for leishmania tropica for epidemiological surveillance of disease.
Haroon Ur Rashid   +5 more
doaj   +1 more source

Coumarin‐Benzimidazole Hybrids as Multitarget Scaffolds for Antileishmanial Drug Discovery

open access: yesChemistrySelect, Volume 11, Issue 38, 13 October 2026.
Coumarin‐benzimidazole hybrids emerge as promising antileishmanial agents through virtual screening against essential Leishmania enzymes, Cathepsin B (CatB), and N‐myristoyltransferase (NMT). Molecular docking and dynamics simulations reveal highly stable target interactions that surpass the reference drug miltefosine (MTF).
Fernanda Melo Jucá   +4 more
wiley   +1 more source

Antimicrobial Activity of Locally Synthesized Carbon Nanosphere on Some Pathogenic Species of Bacteria and Parasites

open access: yesمجلة بغداد للعلوم, 2021
Antibacterial activity of CNSs against Staphylococcus aureus and Escherichia coli was estimated. Higher inhibition zone of 18 mm and 20 mm were observed against S.
Ali Taha   +3 more
doaj   +1 more source

Synthesis, Anti‐Leishmania amazonensis Activity, Cytotoxicity, and Molecular Docking of Anthranilate–Naphthoquinone Hybrids

open access: yesChemistrySelect, Volume 11, Issue 40, 27 October 2026.
New anthranilate–naphthoquinone hybrids display potent inhibition of Leishmania (L.) amazonensis with low host cell toxicity. Molecular docking reveals key interactions with TR, GP63, and PTR1, suggesting a multitarget mechanism that contributes to parasite death.
Eduardo Miranda da Silva Magesfeste   +7 more
wiley   +1 more source

Ruminants Epidemiology, Spatial Clustering and Multivariate Risk Modelling of Cutaneous Leishmaniasis in District Bajaur, Pakistan

open access: yesVeterinary Medicine and Science, Volume 12, Issue 4, July 2026.
This study investigated the epidemiology, risk factors and spatial distribution of cutaneous leishmaniasis in District Bajaur, Pakistan. Higher prevalence was observed among young males during summer, with lesions mainly on exposed body parts. Spatial analysis identified Khar, Loe Mamund and Salarzai as hotspots, highlighting the need for targeted ...
Murad Ali Khan   +10 more
wiley   +1 more source

Investigating the Existence of Ribosomal Protein L5 Gene in Syrian Strain of Leishmania tropica Genome: Sequencing It and Evaluating Its Immune Response as DNA Vaccine

open access: yesJournal of Parasitology Research, 2021
Cutaneous leishmaniasis in Syria is caused mainly by Leishmania tropica. It represents a serious health problem, which has aggravated further after the civil war in the country.
Mohammad Maarouf, Alyaa A. Abdlwahab
doaj   +1 more source

Transcriptional signatures in human macrophage-like cells infected by Leishmania infantum, Leishmania major and Leishmania tropica. [PDF]

open access: yesPLoS Negl Trop Dis
Background: In the Mediterranean basin, three Leishmania species have been identified: L. infantum, L. major and L. tropica, causing zoonotic visceral leishmaniasis (VL), zoonotic cutaneous leishmaniasis (CL) and anthroponotic CL, respectively.
Diotallevi A   +10 more
europepmc   +2 more sources

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