Development of a LAMP assay for detection of Leishmania infantum infection in dogs using conjunctival swab samples [PDF]
Background: Leishmania infantum infections in dogs play a crucial role in the transmission of pathogens causing visceral leishmaniasis to humans in the Gansu province, northwest China. To be able to control zoonotic transmission of the parasite to humans,
A Moshfe +48 more
core +1 more source
Cutaneous leishmaniasis in Syria is caused mainly by Leishmania tropica. It represents a serious health problem, which has aggravated further after the civil war in the country.
Mohammad Maarouf, Alyaa A. Abdlwahab
doaj +1 more source
Structural basis of secreted acid phosphatase polymerization in the Leishmania parasite
Abstract Enzymes that assemble into filaments typically transition between protomeric and polymeric states in response to cellular conditions. In contrast, the secreted acid phosphatase (SAP) of Leishmania, one of the most abundant extracellular glycoproteins produced by the parasite and regarded as a major virulence factor in the neglected tropical ...
Priyanka Bose +4 more
wiley +1 more source
In Vitro Evaluation of Antileishmanial Activity of Commiphora myrrha Essential Oil Nanoliposome
This study investigates the efficacy of nanoliposomal formulations containing myrrh essential oil in combating Leishmania protozoa in laboratory settings. Myrrh essential oil and nanoliposomes were prepared in RPMI‐1640 medium at concentrations of 1, 2, 5 and 10 µg/dL.
Zahra Akbari +2 more
wiley +1 more source
The Genetic Relationship between Leishmania aethiopica and Leishmania tropica Revealed by Comparing Microsatellite Profiles [PDF]
Background Leishmania (Leishmania) aethiopica and L. (L.) tropica cause cutaneous leishmaniases and appear to be related. L. aethiopica is geographically restricted to Ethiopia and Kenya; L.
Krayter, Lena +2 more
core +6 more sources
In vitro and in vivo antileishmanial effects of Pistacia khinjuk against Leishmania tropica and Leishmania major [PDF]
The present study aims to evaluate the in vitro and in vivo antileishmanial activities of Pistacia khinjuk Stocks (Anacardiaceae) alcoholic extract and to compare its efficacy with a reference drug, meglumine antimoniate (MA, Glucantime), against ...
Azadpour, Mojgan. +4 more
core +3 more sources
Mixed Mucosal Leishmaniasis Infection Caused by Leishmania tropica and Leishmania major [PDF]
ABSTRACT Mixed infections with different Leishmania species could explain differences in the clinical courses of these infections. On identification of Leishmania parasites from Iranian patients with mucosal leishmaniasis (ML), a patient with both oral and nasal lesions was found to
Sadegh, Shirian +3 more
openaire +2 more sources
Brain Involvement in Leishmaniasis
ABSTRACT Leishmaniasis is a neglected tropical disease caused by infection with the protozoan parasite Leishmania and it is a significant global health problem. The disease has a wide clinical spectrum, from tegumentary leishmaniasis (TL) that encompasses cutaneous (CL), mucosal (ML) and cutaneous‐diffuse (CDL) forms, to the potentially fatal systemic ...
Camila S. Freitas +2 more
wiley +1 more source
Domestic dog ownership in Iran is a risk factor for human infection with Leishmania infantum. [PDF]
One explanation proposed for the widespread failure to control zoonotic visceral leishmaniasis by culling infected domestic dogs is that wild canids or humans play significant roles in transmission.
Davies, Clive R +4 more
core +1 more source
Leishmania Extracellular Vesicles as a Preventive Vaccine Platform Against Leishmaniasis
The potential of Leishmania‐derived extracellular vesicles (EVs) as a vaccine platform was investigated, emphasizing an affordable, GMP‐compliant production and purification method. Immunization with EV vaccines, either unadjuvanted or combined with α‐galactosylceramide (αGC), induced robust humoral and cellular immune responses, conferring protection ...
Ismail Cem Yilmaz +24 more
wiley +1 more source

