Results 51 to 60 of about 2,272 (172)

Leishmania Extracellular Vesicles as a Preventive Vaccine Platform Against Leishmaniasis

Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
The potential of Leishmania‐derived extracellular vesicles (EVs) as a vaccine platform was investigated, emphasizing an affordable, GMP‐compliant production and purification method. Immunization with EV vaccines, either unadjuvanted or combined with α‐galactosylceramide (αGC), induced robust humoral and cellular immune responses, conferring protection ...
Ismail Cem Yilmaz, Ibrahim Tokmak, Muzaffer Yildirim, Tugce Canavar Yildirim, Elif Sena Ozkoc, Irem Evcili, Emre Mert Ipekoglu, İhsan Cihan Ayanoglu, Emre Dunuroglu, Dicle Caliskan, Harun Onler, Zeynep Arzum, Ceren Ulker, Olcay Mert, Ridvan Orkut, Ibrahim Oguzhan Tarman, Ulku Guler, Bekir Salih, Volkan Yazar, Gokcen Ozgun, Serap Birincioglu, Ahmet Ozbilgin, Bilgi Gungor, Ihsan Gursel, Mayda Gursel   +24 more
wiley   +1 more source

Spatial Distribution and Molecular Identification of Leishmania Species from Endemic Foci of South-Eastern Iran [PDF]

Iranian Journal of Parasitology, 2012
Background: Cutaneous leishmaniasis constitutes a major public health problem in many parts of the world including Iran. The primary objective of this study was to identify Leishmania spe­cies in endemic districts of Kerman Province, south-eastern Iran.
F Sharifi, I Sharifi, M Zarean, M Hakimi Parizi, MR Aflatoonian, M Fasihi Harandi, R Zahmatkesh, M Mashayekhi, AR Kermanizadeh   +8 more
doaj   +1 more source

The molecular epidemiology and phylogeography of Trypanosoma cruzi and parallel research on Leishmania: looking back and to the future. [PDF]

, 2009
Trypanosoma cruzi is the protozoan agent of Chagas disease, and the most important parasitic disease in Latin America. Protozoa of the genus Leishmania are global agents of visceral and cutaneous leishmaniasis, fatal and disfiguring diseases.
Fitpatrick, S., Miles, M.A., Fitzpatrick, S, Mauricio, IL, Yeo, M., Gaunt, MW, Mauricio, I.L., Llewellyn, MS, Lewis, MD, Miles, MA, Baleela, R, Lewis, M.D., Gaunt, M.W., Yeo, M, Baleela, R., Llewellyn, M.S.   +15 more
core   +1 more source

Lupoid leishmaniasis among the known cases of cutaneous leishmaniasis in Herat Province, western Afghanistan

Journal of Infection and Public Health, 2016
Summary: Lupoid cutaneous leishmaniasis (LCL) is an uncommon form of chronic cutaneous leishmaniasis, which is mostly caused by Leishmania tropica in the Old World and has a high incidence throughout early life.
Hossein Pazoki, Mahdi Fakhar, Abobakar Rasooli, Mehdi Karamian, Eisa Nazar   +4 more
doaj   +1 more source

Exploring Novel Nitrofuryl‐1,3,4‐Thiadiazole‐Based Derivatives: Design, Synthesis, and Evaluation of In Vitro Leishmanicidal and Trypanocidal Activity

Archiv der Pharmazie, Volume 359, Issue 3, March 2026.
In a series of substituted 1‐[5‐(5‐nitrofuran‐2‐yl)‐1,3,4‐thiadiazol‐2‐yl]piperidine‐4‐carboxamides evaluated for in vitro antileishmanial and antitrypanosomal activity, compound 18 emerged as the most promising derivative, showing submicromolar anti‐parasitic effects targeting diverse Leishmania and Trypanosoma species and acceptable selectivity ...
Alireza Mousavi, Martina Slapničková, Maryam Norouzbahari, Sarah D'Alessandro, Parham Foroumadi, Fariba Peytam, Federica Perego, Eva Doleželová, Zahra Emamgholipour, Maliheh Barazandeh Tehrani, Seyed Esmaeil Sadat‐Ebrahimi, Elahe Hosseinzadeh, Elmira Meghrazi Ahadi, Loghman Firoozpour, Hamidreza Bijanzadeh, Nicoletta Basilico, Alena Zíková, Alireza Foroumadi   +17 more
wiley   +1 more source

Detection, molecular typing and phylogenetic analysis of Leishmania isolated from cases of leishmaniasis among Syrian refugees in Lebanon

Parasite Epidemiology and Control, 2016
Leishmania is a parasitic protozoan with more than two-dozen species causing the disease leishmaniasis. It is transmitted to humans through the bite of an infected female phlebotomine sand-fly vector.
Tamara Salloum, Ibrahim Khalifeh, Sima Tokajian   +2 more
doaj   +1 more source

Arginase activity in pathogenic and non-pathogenic species of Leishmania parasites. [PDF]

PLoS Neglected Tropical Diseases, 2017
Proliferation of Leishmania (L.) parasites depends on polyamine availability, which can be generated by the L-arginine catabolism and the enzymatic activity of arginase (ARG) of the parasites and of the mammalian hosts.
Alireza Badirzadeh, Tahereh Taheri, Yasaman Taslimi, Zahra Abdossamadi, Maryam Heidari-Kharaji, Elham Gholami, Baharehsadat Sedaghat, Maryam Niyyati, Sima Rafati   +8 more
doaj   +1 more source

Zinc Oxide Nanomaterials: Green Synthesis, Properties, and Potentials in Active Food Packaging, Edible Coatings, and Nanomedicine Applications

ChemistrySelect, Volume 11, Issue 1, 8 January 2026.
This study critically analyzed the main advances in ZnO nanomaterials obtained from different synthetic approaches (mediated by plants, microbes and seaweeds), and their functional and biological properties were prospected for applications in the food and nanomedicine sector.
Italo Rennan Sousa Vieira, Ana Carolina de Morais Mirres, Carlos Adam Conte‐Junior   +2 more
wiley   +1 more source

Phytotherapy in Leishmania infantum and Leishmania tropica [PDF]

, 2017
Leishmaniasis is a tropical zoonotic disease, transferred from conveyer sandflies. Cutaneous Leishmaniasis is the second common disease after malaria, prevalent in many tropical countries of the world.
Rafieian-Kopaei, M., Abdi, J., Naserifar, R., Bahmani, M., Abbaszadeh, S., Adineh, S. H.   +5 more
core  

Molecular detection of Leishmania species in human and animals from cutaneous leishmaniasis endemic areas of Waziristan, Khyber Pakhtunkhwa, Pakistan

Asian Pacific Journal of Tropical Medicine, 2018
Objectives: To detect Leishmania species in human patients, animal reservoirs and Phlebotomus sandflies in Waziristan, Pakistan. Methods: Tissue smears and aspirates from 448 cutaneous leishmaniasis (CL) suspected patients were analyzed. To sort out role
Mubashir Hussain, Shahzad Munir, Abdullah Jalal, Taj Ali Khan, Niaz Muhammad, Bahar Ullah Khattak, Abdullah Khan, Irfan Ahmed, Zulqarnain Baloch, Nawaz Haider Bashir, Muhammad Ameen Jamal, Kashif Rahim, Humaira Mazhar, Maira Riaz, Noha Watany   +14 more
doaj   +1 more source