Results 51 to 60 of about 68,163 (199)
Thymus and Leishmania at the Crossroads: Autoimmunity and Cancer
Immunology, Volume 178, Issue 3, Page 377-386, July 2026.Conceptual ‘Crossroads Model’ linking Leishmania, thymic infection and immune dysregulation: an integrative model is proposed in which Leishmania infection disrupts thymic architecture and stromal–thymocyte interactions. These alterations converge to promote defective tolerance, increased autoimmune risk and a microenvironment permissive to malignant ...
Alef Batista Bezerra Barros +5 more
wiley +1 more source
, 2001 Leishmania tropica, which is endemic in Turkey, is the causative agent of cutaneous leishmaniasis. Leishmania tropica promastigotes (2 x 10(7)) isolated from a patient with dermal leishmaniasis and reproduced in NNN medium were inoculated subcutaneously ...
Ozbilgin, A +4 more
core +1 more source
Clinical Case Reports, Volume 14, Issue 5, May 2026.ABSTRACT In patients with atypical ulcers and travel history to endemic areas, a comprehensive diagnostic workup for cutaneous leishmaniasis is imperative. This case confirms Leishmania tropica through combined microscopy, culture, and PCR, leading to successful treatment with systemic glucantime and adjunctive wound care.
Hossein Pazoki +3 more
wiley +1 more source
Identification of Leishmania tropica and Leishmania aethiopica by DNA sequencing and the detection of Leishmania RNA Virus [PDF]
, 2018 Leishmaniasis is a neglected tropical disease and a major cause of morbidity and mortality in impoverished countries. Leishmaniasis is a global disease and is clinically and epidemiologically diverse, with many different species of Leishmania affecting ...
Bates, Paul, Thomas, Megan
core +2 more sources
Structural basis of secreted acid phosphatase polymerization in the Leishmania parasite
Protein Science, Volume 35, Issue 5, May 2026.Abstract Enzymes that assemble into filaments typically transition between protomeric and polymeric states in response to cellular conditions. In contrast, the secreted acid phosphatase (SAP) of Leishmania, one of the most abundant extracellular glycoproteins produced by the parasite and regarded as a major virulence factor in the neglected tropical ...
Priyanka Bose +4 more
wiley +1 more source
In Vitro Evaluation of Antileishmanial Activity of Commiphora myrrha Essential Oil Nanoliposome
Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.This study investigates the efficacy of nanoliposomal formulations containing myrrh essential oil in combating Leishmania protozoa in laboratory settings. Myrrh essential oil and nanoliposomes were prepared in RPMI‐1640 medium at concentrations of 1, 2, 5 and 10 µg/dL.
Zahra Akbari +2 more
wiley +1 more source
Peptides as a Therapeutic Alternative Against Leishmaniasis: A Scoping Review
Chemical Biology &Drug Design, Volume 107, Issue 5, May 2026.This scoping review of 79 studies identified 231 antimicrobial peptides with anti‐Leishmania activity, including natural‐derived and synthetic peptides (inspired by natural sources or developed through rational design). Most were evaluated in vitro against promastigote and/or amastigote forms, with synthetic peptides showing a more promising effect ...
Maria Eduarda da Veiga Oliveira +3 more
wiley +1 more source
Leishmania tropica infection within fed and unfed Phlebotomus sergenti females.
, 2015 (* = pool)Leishmania tropica infection within fed and unfed Phlebotomus sergenti females.
Haddou Nhammi (715266) +6 more
core +1 more source
Microorganisms, 2021 Polymorphonuclear neutrophils (PMNs) are the first phagocyte recruited and infected by Leishmania. They synthetize superoxide anions (O2−) under the control of the NADPH oxidase complex. In Morocco, Leishmania major and L.
Hasnaa Maksouri +7 more
doaj +1 more source
Aminophthalocyanine-Mediated Photodynamic Inactivation of Leishmania tropica [PDF]
Antimicrobial Agents and Chemotherapy, 2016 ABSTRACT Photodynamic inactivation of Leishmania spp. requires the cellular uptake of photosensitizers, e.g., endocytosis of silicon(IV)-phthalocyanines (PC) axially substituted with bulky ligands. We report here that when substituted with amino-containing ligands, the PCs (PC1 and PC2) were endocytosed ...
Ahmed, Al-Qahtani +8 more
openaire +2 more sources