Results 61 to 70 of about 16,790 (217)

Arginase activity in pathogenic and non-pathogenic species of Leishmania parasites. [PDF]

PLoS Neglected Tropical Diseases, 2017
Proliferation of Leishmania (L.) parasites depends on polyamine availability, which can be generated by the L-arginine catabolism and the enzymatic activity of arginase (ARG) of the parasites and of the mammalian hosts.
Alireza Badirzadeh, Tahereh Taheri, Yasaman Taslimi, Zahra Abdossamadi, Maryam Heidari-Kharaji, Elham Gholami, Baharehsadat Sedaghat, Maryam Niyyati, Sima Rafati   +8 more
doaj   +1 more source

Leishmaniasis in Morocco: Epidemiology, Transmission Dynamics, and the Potential of Artificial Intelligence for Disease Management

Journal of Parasitology Research, Volume 2026, Issue 1, 2026.
Leishmaniases are neglected tropical diseases caused by Leishmania parasites and transmitted by infected phlebotomine sand flies, and they remain a major public health challenge in Morocco. The burden is dominated by cutaneous leishmaniasis (CL) and visceral leishmaniasis (VL), mainly associated with Leishmania major, Leishmania tropica, and L ...
Chaymaa Harkat, Denis Sereno, Abdelmohcine Aimrane, Moulay Abdelmonaim Hidan, Mohamed Yamani, Kholoud Kahime, J.M.P. Barçante   +6 more
wiley   +1 more source

Detection, molecular typing and phylogenetic analysis of Leishmania isolated from cases of leishmaniasis among Syrian refugees in Lebanon

Parasite Epidemiology and Control, 2016
Leishmania is a parasitic protozoan with more than two-dozen species causing the disease leishmaniasis. It is transmitted to humans through the bite of an infected female phlebotomine sand-fly vector.
Tamara Salloum, Ibrahim Khalifeh, Sima Tokajian   +2 more
doaj   +1 more source

Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection. [PDF]

, 1994
Leishmania major are intramacrophage parasites whose eradication requires the induction of T helper 1 (Th1) effector cells capable of activating macrophages to a microbicidal state.
Locksley, RM, Reiner, SL, Stowring, L, Wang, ZE, Zheng, S   +4 more
core   +1 more source

Optimizing a Conventional Multiplex PCR for Simultaneous Detection of Granulomatous Skin Infection Agents: Leishmania aethiopica, Mycobacterium leprae, and Mycobacterium tuberculosis

Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.
Background Conventional polymerase chain reaction (PCR) assays are well‐established molecular techniques that can be integrated as standard diagnostic tools, especially in referral settings. This study aimed to assess the diagnostic potential of a multiplex PCR (mPCR) assay for the diagnosis of cutaneous leishmaniasis (CL), skin tuberculosis, and ...
Selfu Girma, Mesfin Gemeda, Adugna Woldesemayat, Dawit Alemayehu, Dinksira Deneke, Semira Mekonen, Shimelis Doni, Hanna Beliye, Feleke Tilahun Zewdu, Tsegaye Kumssa, Tizita Kidane, Menberework Chanyalew, Almeseged Abdissa, Markos Alemayehu, Kidist Bobosha, Endalamaw Gadisa, Zhengwei Huang   +16 more
wiley   +1 more source

Molecular detection of Leishmania species in human and animals from cutaneous leishmaniasis endemic areas of Waziristan, Khyber Pakhtunkhwa, Pakistan

Asian Pacific Journal of Tropical Medicine, 2018
Objectives: To detect Leishmania species in human patients, animal reservoirs and Phlebotomus sandflies in Waziristan, Pakistan. Methods: Tissue smears and aspirates from 448 cutaneous leishmaniasis (CL) suspected patients were analyzed. To sort out role
Mubashir Hussain, Shahzad Munir, Abdullah Jalal, Taj Ali Khan, Niaz Muhammad, Bahar Ullah Khattak, Abdullah Khan, Irfan Ahmed, Zulqarnain Baloch, Nawaz Haider Bashir, Muhammad Ameen Jamal, Kashif Rahim, Humaira Mazhar, Maira Riaz, Noha Watany   +14 more
doaj   +1 more source

The history of leishmaniasis [PDF]

, 2017
In this review article the history of leishmaniasis is discussed regarding the origin of the genus Leishmania in the Mesozoic era and its subsequent geographical distribution, initial evidence of the disease in ancient times, first accounts of the ...
A Carini, A Lindenberg, A Matta da, A Splendore, AJ Lysenko, AM Cunha da, Anonymous, AR Zink, C Donovan, C Nicolle, CA Hoare, CS Swaminath, D Steverding, DD Cunningham, DG Croan, Dietmar Steverding, DJ Lewis, F Dantas-Torres, FF Tuon, G Edrissian, G Maspero, G Moreno, G Vianna, H Momen, H Noyes, H Noyes, HA Noyes, IL Mauricio, IL Maurício, J Alvar, J Barratt, J Shaw, JF Walsh, JH Wright, JP Nozais, KM Harkins, L Bualert, L Frías, L Lobsiger, LF Schnur, LG Marshall, M Akhoundi, M Boelaert, M Lühe, M Maroli, M Saroufim, MA Costa, ME Gibson, N Desbois, N Müller, P Mansueto, PEC Manson-Bahr, R Du, R Lainson, R Lainson, R Lainson, R Ross, R Ross, RD Kreutzer, RM Nowak, RS Bray, RW Ashford, S Adler, S Leelayoova, SF Kerr, SF Kerr, SM Reuss, T Pothirat, V Thomaz-Soccol, W Twining, W Twining, WB Leishman, WL Yakimoff, WS Al-Salem   +73 more
core   +1 more source

The Safety and Efficacy of an Immunomodulator Garlic‐Based Cream (LeishG1) for Treating Uncomplicated Cutaneous Leishmaniasis: A Single‐Blind, Multi‐Center Study

Health Science Reports, Volume 8, Issue 12, December 2025.
ABSTRACT Background and Aims Cutaneous leishmaniasis (CL) is a major problem in developing nations, particularly in the Middle East. Novel herbal treatment options may provide a safe alternative associated with favorable outcomes in CL lesion healing.
Fatemeh Emadi, Zohreh Khodashenas, Azadeh Rashidi, Ali Khamesipour, Mehdi Zaboli, Mehri Ghafourian, Mohammad Mehdi Naghizadeh, Fatemeh Tuserkani, Tooba Ghazanfari   +8 more
wiley   +1 more source

Leishmania tropica (Kinetoplastida: Trypanosomatidae) - a perplexing parasite [PDF]

Folia Parasitologica, 2003
Leishmania tropica is one of the causative agents of cutaneous leishmaniasis (CL), a disfiguring parasitic disease that recently was found to be viscerotropic. In urban areas it is transmitted from infected individuals by the bite of phlebotomine sand flies to naïve persons (anthroponotic CL). In rural areas animals are thought to be the reservoir, but
openaire   +2 more sources

World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence‐Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis

Veterinary Dermatology, Volume 36, Issue 6, Page 723-787, December 2025.
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis, Gad Baneth, Silvia Colombo, Filipe Dantas‐Torres, Lluís Ferrer, Alessandra Fondati, Guadalupe Miró, Laura Ordeix, Domenico Otranto, Chiara Noli   +9 more
wiley   +1 more source