Results 61 to 70 of about 68,163 (199)

Brain Involvement in Leishmaniasis

Cell Biochemistry and Function, Volume 44, Issue 4, April 2026.
ABSTRACT Leishmaniasis is a neglected tropical disease caused by infection with the protozoan parasite Leishmania and it is a significant global health problem. The disease has a wide clinical spectrum, from tegumentary leishmaniasis (TL) that encompasses cutaneous (CL), mucosal (ML) and cutaneous‐diffuse (CDL) forms, to the potentially fatal systemic ...
Camila S. Freitas, Eduardo A. F. Coelho, Myron Christodoulides   +2 more
wiley   +1 more source

Induction of partial protection against Leishmania major in BALB/c mice by Leishmania tropica” [PDF]

, 2004
Leishmaniasis is a parasitic disease of man and other mammals. Immunity against leishmaniasis appears  to remain essentially species specific; however some cross-reactivity has been reported.
Mahmoudzadeh-Niknam, Hamid
core   +1 more source

Spatial Distribution and Molecular Identification of Leishmania Species from Endemic Foci of South-Eastern Iran [PDF]

Iranian Journal of Parasitology, 2012
Background: Cutaneous leishmaniasis constitutes a major public health problem in many parts of the world including Iran. The primary objective of this study was to identify Leishmania spe­cies in endemic districts of Kerman Province, south-eastern Iran.
F Sharifi, I Sharifi, M Zarean, M Hakimi Parizi, MR Aflatoonian, M Fasihi Harandi, R Zahmatkesh, M Mashayekhi, AR Kermanizadeh   +8 more
doaj   +1 more source

Leishmania Extracellular Vesicles as a Preventive Vaccine Platform Against Leishmaniasis

Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
The potential of Leishmania‐derived extracellular vesicles (EVs) as a vaccine platform was investigated, emphasizing an affordable, GMP‐compliant production and purification method. Immunization with EV vaccines, either unadjuvanted or combined with α‐galactosylceramide (αGC), induced robust humoral and cellular immune responses, conferring protection ...
Ismail Cem Yilmaz, Ibrahim Tokmak, Muzaffer Yildirim, Tugce Canavar Yildirim, Elif Sena Ozkoc, Irem Evcili, Emre Mert Ipekoglu, İhsan Cihan Ayanoglu, Emre Dunuroglu, Dicle Caliskan, Harun Onler, Zeynep Arzum, Ceren Ulker, Olcay Mert, Ridvan Orkut, Ibrahim Oguzhan Tarman, Ulku Guler, Bekir Salih, Volkan Yazar, Gokcen Ozgun, Serap Birincioglu, Ahmet Ozbilgin, Bilgi Gungor, Ihsan Gursel, Mayda Gursel   +24 more
wiley   +1 more source

Lupoid leishmaniasis among the known cases of cutaneous leishmaniasis in Herat Province, western Afghanistan

Journal of Infection and Public Health, 2016
Summary: Lupoid cutaneous leishmaniasis (LCL) is an uncommon form of chronic cutaneous leishmaniasis, which is mostly caused by Leishmania tropica in the Old World and has a high incidence throughout early life.
Hossein Pazoki, Mahdi Fakhar, Abobakar Rasooli, Mehdi Karamian, Eisa Nazar   +4 more
doaj   +1 more source

Arginase activity in pathogenic and non-pathogenic species of Leishmania parasites. [PDF]

PLoS Neglected Tropical Diseases, 2017
Proliferation of Leishmania (L.) parasites depends on polyamine availability, which can be generated by the L-arginine catabolism and the enzymatic activity of arginase (ARG) of the parasites and of the mammalian hosts.
Alireza Badirzadeh, Tahereh Taheri, Yasaman Taslimi, Zahra Abdossamadi, Maryam Heidari-Kharaji, Elham Gholami, Baharehsadat Sedaghat, Maryam Niyyati, Sima Rafati   +8 more
doaj   +1 more source

Promastigote secretory gel from natural and unnatural sand fly vectors exacerbate Leishmania major and Leishmania tropica cutaneous leishmaniasis in mice. [PDF]

, 2019
Leishmania rely heavily on glycans to complete their digenetic life cycle in both mammalian and phlebotomine sand fly hosts. Leishmania promastigotes secrete a proteophosphoglycan-rich gel (Promastigote Secretory Gel, PSG) that is regurgitated during ...
Giraud, E, Svobodová, M, Müller, I, Rogers, ME, Volf, P   +4 more
core   +1 more source

Detection, molecular typing and phylogenetic analysis of Leishmania isolated from cases of leishmaniasis among Syrian refugees in Lebanon

Parasite Epidemiology and Control, 2016
Leishmania is a parasitic protozoan with more than two-dozen species causing the disease leishmaniasis. It is transmitted to humans through the bite of an infected female phlebotomine sand-fly vector.
Tamara Salloum, Ibrahim Khalifeh, Sima Tokajian   +2 more
doaj   +1 more source

Exploring Novel Nitrofuryl‐1,3,4‐Thiadiazole‐Based Derivatives: Design, Synthesis, and Evaluation of In Vitro Leishmanicidal and Trypanocidal Activity

Archiv der Pharmazie, Volume 359, Issue 3, March 2026.
In a series of substituted 1‐[5‐(5‐nitrofuran‐2‐yl)‐1,3,4‐thiadiazol‐2‐yl]piperidine‐4‐carboxamides evaluated for in vitro antileishmanial and antitrypanosomal activity, compound 18 emerged as the most promising derivative, showing submicromolar anti‐parasitic effects targeting diverse Leishmania and Trypanosoma species and acceptable selectivity ...
Alireza Mousavi, Martina Slapničková, Maryam Norouzbahari, Sarah D'Alessandro, Parham Foroumadi, Fariba Peytam, Federica Perego, Eva Doleželová, Zahra Emamgholipour, Maliheh Barazandeh Tehrani, Seyed Esmaeil Sadat‐Ebrahimi, Elahe Hosseinzadeh, Elmira Meghrazi Ahadi, Loghman Firoozpour, Hamidreza Bijanzadeh, Nicoletta Basilico, Alena Zíková, Alireza Foroumadi   +17 more
wiley   +1 more source

The Genetic Relationship between Leishmania aethiopica and Leishmania tropica Revealed by Comparing Microsatellite Profiles. [PDF]

, 2015
Leishmania (Leishmania) aethiopica and L. (L.) tropica cause cutaneous leishmaniases and appear to be related. L. aethiopica is geographically restricted to Ethiopia and Kenya; L.
Schnur, Lionel F., Lionel F. Schnur, Lena Krayter (773555), Gabriele Schönian (50541), Lionel F. Schnur (254944), Krayter, Lena, Lena Krayter, Gabriele Schönian, Lionel F Schnur, Schönian, Gabriele, Schnur Lionel F., Krayter Lena, Schönian Gabriele   +12 more
core   +2 more sources