Results 1 to 10 of about 9,977 (186)

Self-Hybridization in Leishmania major

mBio, 2022
Genetic exchange between different Leishmania strains in the sand fly vector has been experimentally demonstrated and is supported by population genetic studies.
Tiago R. Ferreira, Ehud Inbar, Jahangheer Shaik, Brendan M. Jeffrey, Kashinath Ghosh, Deborah E. Dobson, Stephen M. Beverley, David Sacks   +7 more
doaj   +4 more sources

The in vitro anti-Leishmania Effect of Zingiber officinale Extract on Promastigotes and Amastigotes of Leishmania major and Leishmania tropica

Türkiye Parazitoloji Dergisi, 2022
Objective:Recently, the use of pentavalent antimony compounds for Leishmaniasis treatment has been associated with disease recurrence, drug resistance, and severe side effects. Therefore, there is a need to develop alternative treatment strategies.
Jasem Saki, Elaheh Biranvand, Reza Arjmand   +2 more
doaj   +1 more source

PCR Positivity of Gerbils and Their Ectoparasites for Leishmania Spp. in a Hyperendemic Focus of Zoonotic Cutaneous Leishmaniasis in Central Iran

Journal of Arthropod-Borne Diseases, 2023
Background: Various arthropods, including Rhipicephalus sanguineus and Ctenocephalides felis felis have been sug­gested as secondary vectors of Leishmania spp. many years ago. This study was conducted to determine zoonotic cuta­neous leishmaniasis (ZCL)
Sahar Azarmi, Alireza Zahraei-Ramazani, Mehdi Mohebali, Yavar Rassi, Amir Ahmad Akhavan, Amrollah Azarm, Omid Dehghan, Samira Elikaee, Rahimeh Abdoli, Mohsen Mahmoudi   +9 more
doaj   +1 more source

Molecular Identification of Cutaneous Leishmaniasis Species in the Northcentral Iranian Province of Alborz: Is There a New Focus on Cutaneous Leishmaniasis in the Province?

Iranian Journal of Parasitology, 2023
Background: Cutaneous leishmaniasis (CL) is an endemic infection in the Middle East, including Iran that is also spreading to new foci. We aimed to determine the leishmaniasis species causing CL in Alborz province.
Susan Sheikhi, Aliehsan Heidari, Mehdi Mohebali, Hossein Keshavarz, Amir Heidari, Monireh Sezavar, Behnaz Akhoundi, Amir Bairami   +7 more
doaj   +1 more source

Elimination of LRVs Elicits Different Responses in Leishmania spp.

mSphere, 2022
Leishmaniaviruses (LRVs) have been demonstrated to enhance progression of leishmaniasis, a vector-transmitted disease with a wide range of clinical manifestations that is caused by flagellates of the genus Leishmania.
Andreu Saura, Alexandra Zakharova, Donnamae Klocek, Evgeny S. Gerasimov, Anzhelika Butenko, Diego H. Macedo, Elena Servienė, Diana Zagirova, Anastasia Meshcheryakova, Igor B. Rogozin, Saulius Serva, Alexei Yu. Kostygov, Vyacheslav Yurchenko   +12 more
doaj   +1 more source

The SNARE protein family of Leishmania major [PDF]

BMC Genomics, 2006
Abstract Background Leishmania major is a protozoan parasite with a highly polarised cell shape that depends upon endocytosis and exocytosis from a single area of the plasma membrane, the flagellar pocket.
Besteiro, S., Coombs, G.H., Mottram, J.C.   +2 more
openaire   +4 more sources

Increased transmission potential of Leishmania major/Leishmania infantum hybrids [PDF]

International Journal for Parasitology, 2007
Development of Leishmania infantum/Leishmania major hybrids was studied in two sand fly species. In Phlebotomus papatasi, which supported development of L. major but not L. infantum, the hybrids produced heavy late-stage infections with high numbers of metacyclic promastigotes.
Petr, Volf, Ivana, Benkova, Jitka, Myskova, Jovana, Sadlova, Lenea, Campino, Christophe, Ravel   +5 more
openaire   +2 more sources

Plasmenylethanolamine synthesis in Leishmania major [PDF]

Molecular Microbiology, 2016
SummaryEthanolamine glycerophospholipids are ubiquitous cell membrane components. Trypanosomatid parasites of the genus Leishmania synthesize the majority of their ethanolamine glycerophospholipids as 1‐O‐alk‐1′‐enyl‐2‐acyl‐sn‐glycero‐3‐phosphoethanolamine or plasmenylethanolamine (PME) through the Kennedy pathway.
Pawlowic, Mattie C., Hsu, Fong Fu, Moitra, Samrat, Biyani, Neha, Zhang, Kai   +4 more
openaire   +3 more sources

The nanoemulsion-based nanogel of Artemisia dracunculus essential oil with proper activity against Leishmania tropica and Leishmania major [PDF]

Nanomedicine Research Journal, 2021
Cutaneous leishmaniasis is the most common form of leishmaniasis that is distributed in around 100 countries. Preparing essential oil-based nanoformulations with the leishmanicidal effect is a promising strategy for the development of new drugs.
Ali Ghanbariasad, Sare Azadi, Mahmoud Agholi, Mahmoud Osanloo   +3 more
doaj   +1 more source

L-arginine deprivation impairs Leishmania major-specific T-cell responses. [PDF]

, 2009
The amino acid L-arginine plays a crucial role in the regulation of immune responses. We have recently shown that uncontrolled replication of Leishmania parasites at the site of pathology correlates with high levels of arginase activity in nonhealing ...
Markus Munder, Beak‐San Choi, Munder, Markus, Kropf, Pascale, Choi, Beak-San, Rogers, Matthew, Matthew Rogers, Pascale Kropf   +7 more
core   +1 more source