Updates on Geographical Dispersion of Leishmania Parasites Causing Cutaneous Affections in Algeria
Leishmaniases are neglected tropical diseases of public health concern in Algeria. To update the geographical distribution of Leishmania spp. causing cutaneous affection, we examined a set of Giemsa-stained smears prepared from skin lesions of the ...
Arezki Izri +3 more
doaj +1 more source
The role of leishmania proteophosphoglycans in sand fly transmission and infection of the Mammalian host. [PDF]
Leishmania are transmitted by the bite of their sand fly vector and this has a significant influence on the virulence of the resulting infection. From our studies into the interaction between parasite, vector, and host we have uncovered an important ...
Rogers, Matthew E +2 more
core +1 more source
Cyclic nucleotide specific phosphodiesterases of Leishmania major [PDF]
Abstract Background Leishmania represent a complex of important human pathogens that belong to the systematic order of the kinetoplastida. They are transmitted between their human and mammalian hosts by different bloodsucking sandfly vectors.
Johner A +4 more
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Ecotin-like serine peptidase inhibitor ISP1 of Leishmania major plays a role in flagellar pocket dynamics and promastigote differentiation [PDF]
Leishmania ISPs are ecotin-like natural peptide inhibitors of trypsin-family serine peptidases, enzymes that are absent from the Leishmania genome. This led to the proposal that ISPs inhibit host serine peptidases and we have recently shown that ISP2 ...
Petr Volf +28 more
core +1 more source
ATG5 is essential for ATG8-dependent autophagy and mitochondrial homeostasis in Leishmania major [PDF]
Macroautophagy has been shown to be important for the cellular remodelling required for Leishmania differentiation. We now demonstrate that L. major contains a functional ATG12-ATG5 conjugation system, which is required for ATG8-dependent autophagosome ...
Williams, Roderick A M +23 more
core +1 more source
Comorbidity of Leishmania major with cutaneous sarcoidosis
leishmaniasis infection might manifest as sarcoidosis; on the other hand, some evidences propose an association between sarcoidosis and leishmaniasis. Most of the times, it is impossible to discriminate idiopathic sarcoidosis from leishmaniasis by conventional histopathologic exam.We performed a cross-sectional study to examine the association of ...
Hamideh Moravvej +4 more
openaire +3 more sources
From genomes to vaccines: Leishmania as a model:Leishmania as a model [PDF]
The 35 Mb genome of Leishmania should be sequenced by late 2002. It contains approximately 8500 genes that will probably translate into more than 10 000 proteins.
Vilo, Jaak +11 more
core +1 more source
Changes in the Epidemiology of Cutaneous Leishmaniasis in Northeastern Iran
The province of Khorasan-Razavi in the North East of Iran is an endemic area for anthroponotic cutaneous leishmaniasis (ACL caused mainly by Leishmania tropica) and zoonotic cutaneous leishmaniasis (ZCL caused mainly by Leishmania major).
Bibi Razieh Hosseini Farash +10 more
doaj +1 more source
Leishmania major, the Predominant Leishmania Species Responsible for Cutaneous Leishmaniasis in Mali [PDF]
Leishmania major is the only species of Leishmania known to cause cutaneous leishmanisis (CL) in Mali. We amplified Leishmania DNA stored on archived Giemsa-stained dermal scraping slides obtained from self-referral patients with clinically suspected CL seen in the Center National d'Appui A La Lutte Contre La Maladie (CNAM) in Bamako, Mali, to ...
Carlos, Paz +9 more
openaire +2 more sources
Comparative Gene Expression Profiles of Leishmania major and Leishmania infantum Promastigotesa
This study aimed to determine the differences between the gene expression profiles of Leismania major and Leishmania infantum promastigotes through comparative analysis of gene expressions.Cell culture of L. major (MHOM/IL/80) and L. infantum (MHOM/MA/67/ITMAP/263) cell lines was performed.
Özlem Ulusan Bağcı +2 more
openaire +3 more sources

